Cinalukast

Tocris Bioscience, part of Bio-Techne | Catalog # 2025

Potent, selective CysLT1 (LTD4) antagonist; orally active
Discontinued Product
2025 has been discontinued. View all Leukotriene and Related Receptor Antagonists products.

Key Product Details

Description

Potent, selective CysLT1 (LTD4) antagonist; orally active

Alternative Names

Ro 24-5913

View all Leukotriene and Related Receptor Antagonists »

Product Description

Potent, selective CysLT1 (LTD4) leukotriene receptor antagonist (IC50 = 6.4 nM). Inhibits LTD4-induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.

Product Specifications

Molecular Weight

412.55

Formula

C23H28N2O3S

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid

CAS Number

128312-51-6

PubChem ID

6436135

InChI Key

BZMKNPGKXJAIDV-VAWYXSNFSA-N

SMILES

CCC(CC)(CC(=O)NC1=CC(\C=C\C2=NC(=CS2)C2CCC2)=CC=C1)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.26 100
Ethanol 4.13 10

Preparing Stock Solutions for Cinalukast

The following data is based on the product molecular weight 412.55

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL
10 mM 0.24 mL 1.21 mL 2.42 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Cinalukast

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cinalukast

For research use only

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