Cimetidine

Tocris Bioscience, part of Bio-Techne | Catalog # 0902

H2 antagonist, I1 agonist
Discontinued Product
0902 has been discontinued. View all Histamine H2 Receptor Antagonists products.

Key Product Details

Description

H2 antagonist, I1 agonist

View all Histamine H2 Receptor Antagonists »

Product Description

Cimetidine is a widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand.

Product Specifications

Molecular Weight

252.34

Formula

C10H16N6S

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine

CAS Number

51481-61-9

PubChem ID

2756

InChI Key

AQIXAKUUQRKLND-UHFFFAOYSA-N

SMILES

CN\C(NCCSCC1=C(C)NC=N1)=N\C#N

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 50
DMSO 25.23 100

Preparing Stock Solutions for Cimetidine

The following data is based on the product molecular weight 252.34

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.96 mL 19.81 mL 39.63 mL
5 mM 0.79 mL 3.96 mL 7.93 mL
10 mM 0.40 mL 1.98 mL 3.96 mL
50 mM 0.08 mL 0.40 mL 0.79 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product.

Product Documents for Cimetidine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cimetidine

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.