Chaetoglobosin A

Name: Chaetoglobosin A
Brand: Tocris Bioscience
SKU: 5804
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 5804

(1)

COA / SDS

Antibiotic; selectively induces apoptosis of CLL cells

Discontinued Product

5804 has been discontinued. View all Antibiotics products.

Key Product Details

Description:	Antibiotic; selectively induces apoptosis of CLL cells
Chemical Name:	(1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-4,7,14,14a,15,15a,16a,16b-Octahydro-7-hydroxy-14-(1H-indol-3-ylmethyl)-4,6,15,15a-tetramethyl-3H-cyclotridec[d]oxireno[f]isoindole-8,11,12(13H)-trione
Purity:	≥98% (HPLC)
Molecular Weight:	528.64

View Full Technical Details for Chaetoglobosin A

Technical Data
Citations / Reviews (1)

Biological Activity for Chaetoglobosin A

Chaetoglobosin A is an antibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G₂ phase.

Technical Data for Chaetoglobosin A

M. Wt	528.64
Formula	C₃₂H₃₆N₂O₅
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	50335-03-0
PubChem ID	102601376
InChi Key	OUMWCYMRLMEZJH-VOXRAUTJSA-N
Smiles	O=C1[C@]23[C@]([H])([C@H](CC4=CNC5=CC=CC=C45)N1)[C@H](C)[C@]6(C)[C@]([H])([C@@]2(/C=C/C[C@H](C)/C=C(C)/[C@@H](O)C(/C=C/C3=O)=O)[H])O6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Chaetoglobosin A

References are publications that support the biological activity of the product.

Knudsen Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 2014 PMID: 24280868

Chaetoglobosin A

Tocris Bioscience, part of Bio-Techne | Catalog # 5804

Key Product Details

Biological Activity for Chaetoglobosin A

Technical Data for Chaetoglobosin A

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Chaetoglobosin A

Product Documents for Chaetoglobosin A

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected