CB 13

Name: CB 13
Brand: Tocris Bioscience
SKU: 2928

Tocris Bioscience, part of Bio-Techne | Catalog # 2928

Citations (8)

COA / SDS

Potent dual CB1/CB2 agonist

Discontinued Product

2928 has been discontinued. View all Non-selective Cannabinoid Receptor Agonists products.

Key Product Details

Description:	Potent dual CB₁/CB₂ agonist
Chemical Name:	1-Naphthalenyl[4-(pentyloxy)-1-naphthalenyl]methanone
Purity:	≥99% (HPLC)
Molecular Weight:	368.47

View Full Technical Details for CB 13

Technical Data
Citations

Biological Activity for CB 13

CB 13 is a potent, orally active CB₁/CB₂ receptor agonist with limited brain penetration (EC₅₀ values are 6.1 and 27.9 nM for CB₁ and CB₂ receptors respectively). Displays antihyperalgesic activity in a rat model of neuropathic pain with no CNS side effects.

Technical Data for CB 13

M. Wt	368.47
Formula	C₂₆H₂₄O₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	432047-72-8
PubChem ID	9799417
InChi Key	RSUMDJRTAFBISX-UHFFFAOYSA-N
Smiles	O=C(C3=CC=CC4=C3C=CC=C4)C2=CC=C(OCCCCC)C1=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for CB 13

References are publications that support the biological activity of the product.

Cluny Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a peripherally restricted cannabinoid CB₁/CB₂ receptor agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice. J.Pharmacol.Exp.Ther. 2010 PMID: 20571060
Dziadulewicz Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB₁/CB₂ dual agonist with antihyperalgesic properties and restricted central nervous system penetration. J.Med.Chem. 2007 PMID: 17630726

CB 13

Tocris Bioscience, part of Bio-Techne | Catalog # 2928

Key Product Details

Biological Activity for CB 13

Technical Data for CB 13

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for CB 13

Product Documents for CB 13

COA

Certificate of Analysis

SDS

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