Carbazeran citrate

Name: Carbazeran citrate
Brand: Tocris Bioscience
SKU: 4420

Tocris Bioscience a Bio-Techne Brand

Catalog # 4420

COA / SDS

Catalog #

Availability

Size / Price

Qty

Key Product Details

Description:	Aldehyde oxidase substrate; PDE inhibitor
Chemical Name:	Ethyl 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl carbamate citrate
Purity:	≥98% (HPLC)
Molecular Weight:	552.53

View Full Technical Details for Carbazeran citrate

Biological Activity for Carbazeran citrate

Carbazeran citrate is an aldehyde oxidase (AO) substrate. Exhibits activities as a phosphodiesterase inhibitor; produces concentration-dependent positive inotropic responses in isolated right atria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data for Carbazeran citrate

M. Wt	552.53
Formula	C₁₈H₂₄N₄O₄.C₆H₈O₇
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	153473-94-0
PubChem ID	90488940
InChi Key	QKMRPDVEKBYWPF-UHFFFAOYSA-N
Smiles	O=C(NCC)OC(CC3)CCN3C2=NN=CC1=CC(OC)=C(OC)C=C12.OC(CC(C(O)=O)(O)CC(O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Carbazeran citrate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	27.63	50
	DMSO	55.25	100

Preparing Stock Solutions for Carbazeran citrate

The following data is based on the product molecular weight 552.53.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.81 mL	9.05 mL	18.10 mL
5 mM	0.36 mL	1.81 mL	3.62 mL
10 mM	0.18 mL	0.90 mL	1.81 mL
50 mM	0.04 mL	0.18 mL	0.36 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Carbazeran citrate

References are publications that support the biological activity of the product.

Hutzler Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes. Drug Metab.Dispos. 2011 PMID: 22031625
Shahid and Rodger Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition. Br.J.Pharmacol. 1989 PMID: 2478244

Citations for Carbazeran citrate

Please visit our Instrument Citation Database to search our collection of scientific articles that feature our instruments.