Bicifadine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 4357

Noradrenalin, 5-HT and dopamine re-uptake inhibitor
Discontinued Product
4357 has been discontinued. View all Adrenergic Transporter Inhibitors products.

Key Product Details

Description

Noradrenalin, 5-HT and dopamine re-uptake inhibitor

View all Adrenergic Transporter Inhibitors »

Product Description

Bicifadine hydrochloride is a potent antagonist of the noradrenalin transporter (IC50 = 55 nM); also displays antagonist activity at the 5-HT and dopamine transporters (IC50 values are 117 nM and 910 nM respectively). Orally active. Exhibits antinociceptive and antiallodynic activity in rodent models of acute, persistent, and chronic pain.

Product Specifications

Molecular Weight

209.72

Formula

C12H15N.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

1-(4-Methylphenyl)-3-azabicyclo[3.1.0]hexane hydrochloride

CAS Number

66504-75-4

PubChem ID

47952

InChI Key

OTZOPAFTLUOBOM-UHFFFAOYSA-N

SMILES

CC(C=C3)=CC=C3C12CNCC1C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 20.97 100
DMSO 20.97 100

Preparing Stock Solutions for Bicifadine hydrochloride

The following data is based on the product molecular weight 209.72

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.77 mL 23.84 mL 47.68 mL
5 mM 0.95 mL 4.77 mL 9.54 mL
10 mM 0.48 mL 2.38 mL 4.77 mL
50 mM 0.10 mL 0.48 mL 0.95 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Bicifadine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Bicifadine hydrochloride

For research use only

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