BHQ
Tocris Bioscience, part of Bio-Techne | Catalog # 1236
Inhibitor of SERCA ATPase
Discontinued Product
1236 has been discontinued.
View all Ca2+-ATPase Inhibitors products.
Product Description
BHQ is a selective inhibitor of endoplasmic reticulum Ca2+-ATPase.Product Specifications
Molecular Weight
222.33
Formula
C14H22O2
Storage
Store at RT
Chemical Name
1,4-Dihydroxy-2,5-di-tert-butylbenzene
CAS Number
88-58-4
PubChem ID
2374
InChI Key
JZODKRWQWUWGCD-UHFFFAOYSA-N
SMILES
CC(C)(C)C1=CC(O)=C(C=C1O)C(C)(C)C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100 |
Preparing Stock Solutions
for BHQ
The following data is based on the product molecular weight 222.33
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.50 mL | 22.49 mL | 44.98 mL |
| 5 mM | 0.90 mL | 4.50 mL | 9.00 mL |
| 10 mM | 0.45 mL | 2.25 mL | 4.50 mL |
| 50 mM | 0.09 mL | 0.45 mL | 0.90 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Jan Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced Ca2+ signals in Madin Darby canine kidney cells. Eur.J.Pharmacol. 1999 PMID: 9988129
- Fusi 2,5-Di-t-butyl-1,4 benzohydroquinone induces endothelium-dependent relaxation of rat thoracic aorta. Eur.J.Pharmacol. 1999 PMID: 10082199
- Hassessian Blockade of the inward rectifier potassium current by the Ca2+-ATPase inhibitor 2',5'-di(tert-butyl)-1,4-benzohydroquinone (BHQ). Br.J.Pharmacol. 1994 PMID: 7952872
- Dettbarn and Palade Effects of three sarcoplasmic/endoplasmic Ca++ pump inhibitors on release channels and intracellular stores. J.Pharmacol.Exp.Ther. 1999 PMID: 9580621
Product Specific Notices for BHQ
For research use only
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