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BHQ

Tocris Bioscience a Bio-Techne Brand

BHQ | CAS No. 88-58-4 | Inhibitor of SERCA ATPase
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Key Product Details

Description: Inhibitor of SERCA ATPase
Chemical Name: 1,4-Dihydroxy-2,5-di-tert-butylbenzene
Molecular Weight: 222.33

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Citations for BHQ (3)

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  • BHQ depletes ER Ca2+ store in HEK cells leading to STIM1-Orai1 clustering for store-operated Ca2+ entry.
    Name: Niroj Shrestha
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HEK293
    ER resident protein, STIM1 and PM resident Orai1 channel were expressed with YFP and CFP fluorescent tags respectively in HEK293 cells and imaged using TIRF microscopy. Basal STIM1 and Orai1 (left) co-clusters to form punctae at PM-ER junctions upon ER store depletion (right) by BHQ (30 µM), leading to store-operated Ca2+ entry through Orai1.
    BHQ Serum 1236

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Product Documents for BHQ

Certificate of Analysis

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