[bAla⁸]-Neurokinin A(4-10)

Name: [bAla 8 ]-Neurokinin A(4-10)
Brand: Tocris Bioscience
SKU: 1640

Tocris Bioscience, part of Bio-Techne | Catalog # 1640

Citations (4715)

COA / SDS

NK2 agonist

Discontinued Product

1640 has been discontinued. View all NK2 Receptor Agonists products.

Key Product Details

Description:	NK₂ agonist
Alternative Names:	MEN 10210
Molecular Weight:	780.93

View Full Technical Details for [bAla⁸]-Neurokinin A(4-10)

Technical Data
Citations

Biological Activity for [bAla⁸]-Neurokinin A(4-10)

[bAla⁸]-Neurokinin A(4-10) is a NK₂ receptor agonist (pD₂ = 6.91). Produces bladder contraction and bronchospasm in guinea pigs in vivo.

Technical Data for [bAla⁸]-Neurokinin A(4-10)

M. Wt	780.93
Formula	C₃₅H₅₆N₈O₁₀S
Single Letter Sequence	DSFVALM (Modifications: Ala-5 = β-Ala, Met-7 = C-terminal amide)
Storage	Desiccate at -20°C
CAS Number	122063-01-8
PubChem ID	9987795
InChi Key	CKNPSJOMUQBPLA-WTWMNNMUSA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for [bAla⁸]-Neurokinin A(4-10)

References are publications that support the biological activity of the product.

Maggi In vivo pharmacology of [βAla⁸]neurokinin A-(4-10), a selective NK-2 tachykinin receptor agonist. Eur.J.Pharmacol. 1990 PMID: 2160369
Rovero A potent and selective agonist for NK-2 tachykinin receptor. Peptides 1989 PMID: 2550911
Carini Tachykinin NK₂ receptors and enhancement of cholinergic transmission in the inflamed rat colon: an in vivo motility study. Br.J.Pharmacol. 2001 PMID: 11487522

[bAla⁸]-Neurokinin A(4-10)

Tocris Bioscience, part of Bio-Techne | Catalog # 1640

Key Product Details

Biological Activity for [bAla⁸]-Neurokinin A(4-10)

Technical Data for [bAla⁸]-Neurokinin A(4-10)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [bAla⁸]-Neurokinin A(4-10)

Product Documents for [bAla⁸]-Neurokinin A(4-10)

COA

Certificate of Analysis

SDS

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[bAla8]-Neurokinin A(4-10)

Tocris Bioscience, part of Bio-Techne | Catalog # 1640

Key Product Details

Biological Activity for [bAla8]-Neurokinin A(4-10)

Technical Data for [bAla8]-Neurokinin A(4-10)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [bAla8]-Neurokinin A(4-10)

Product Documents for [bAla8]-Neurokinin A(4-10)

COA

Certificate of Analysis

SDS

[bAla⁸]-Neurokinin A(4-10)

Biological Activity for [bAla⁸]-Neurokinin A(4-10)

Technical Data for [bAla⁸]-Neurokinin A(4-10)

References for [bAla⁸]-Neurokinin A(4-10)

Product Documents for [bAla⁸]-Neurokinin A(4-10)