β-Funaltrexamine hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0926
Irreversible and selective μ antagonist
Discontinued Product
0926 has been discontinued.
View all mu Opioid Receptor Antagonists products.
Key Product Details
Description
Irreversible and selective μ antagonist
Alternative Names
β-FNA
Product Description
β-Funaltrexamine hydrochloride is a selective μ opioid receptor antagonist.Licensing Information
Sold with the permission of the University of MinnesotaProduct Specifications
Molecular Weight
490.99
Formula
C25H30N2O6.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(E)-4-[[5α,6β)-17-Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoicacid methyl ester hydrochloride
CAS Number
72786-10-8
PubChem ID
44522395
InChI Key
BIPHUOBUKMPSQR-NQGXHZAGSA-N
SMILES
Cl.[H][C@@]12OC3=C4C(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)\C=C\C(=O)OC)=CC=C3O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.82 | 20 with gentle warming | |
| DMSO | 49.1 | 100 |
Preparing Stock Solutions
for β-Funaltrexamine hydrochloride
The following data is based on the product molecular weight 490.99
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.04 mL | 10.18 mL | 20.37 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.07 mL |
| 10 mM | 0.20 mL | 1.02 mL | 2.04 mL |
| 50 mM | 0.04 mL | 0.20 mL | 0.41 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Takemorei The irreversible narcotic antagonist and reversible agonist properties of the fumarate methyl ester derivative of naltr. Eur.J.Pharmacol. 1981 PMID: 6263637
- Jiang μ Antagonist and κ agonist properties of β-funaltrexamine (β-FNA) in vivo: long lasting spinal analgesia in mice. J.Pharmacol.Exp.Ther. 1990 PMID: 2156986
Product Specific Notices for β-Funaltrexamine hydrochloride
For research use only
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