AS 252424

Name: AS 252424
Brand: Tocris Bioscience
SKU: 3671

Tocris Bioscience, part of Bio-Techne | Catalog # 3671

Citations (53)

COA / SDS

Selective inhibitor of PI 3-kinase γ

Discontinued Product

3671 has been discontinued. View all PI 3-Kinase Inhibitors products.

Key Product Details

Description:	Selective inhibitor of PI 3-kinase γ
Chemical Name:	5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
Purity:	≥98% (HPLC)
Molecular Weight:	305.28

View Full Technical Details for AS 252424

Technical Data
Citations

Biological Activity for AS 252424

AS 252424 is a potent and selective inhibitor of PI 3-kinase γ (IC₅₀ values are 33 and 935 nM for PI 3-Kγ and PI 3-Kα respectively).

Technical Data for AS 252424

M. Wt	305.28
Formula	C₁₄H₈FNO₄S
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	900515-16-4
PubChem ID	11630874
InChi Key	OYYVWNDMOQPMGE-SDQBBNPISA-N
Smiles	OC1=CC(F)=CC=C1C2=CC=C(\C=C3/SC(NC3=O)=O)O2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for AS 252424

References are publications that support the biological activity of the product.

Pomel Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ. J.Med.Chem. 2006 PMID: 16789742
Condliffe Sequential activation of class IB and IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 2005 PMID: 15878979

AS 252424

Tocris Bioscience, part of Bio-Techne | Catalog # 3671

Key Product Details

Biological Activity for AS 252424

Technical Data for AS 252424

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for AS 252424

Product Documents for AS 252424

COA

Certificate of Analysis

SDS

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