[Ala⁹²]-p16 (84-103)

Name: [Ala 92 ]-p16 (84-103)
Brand: Tocris Bioscience
SKU: 1902

Tocris Bioscience, part of Bio-Techne | Catalog # 1902

COA / SDS

Cdk 4 inhibitor peptide; derived from p16

Discontinued Product

1902 has been discontinued. View all Cyclin-dependent Kinase Inhibitors products.

Key Product Details

Description:	Cdk 4 inhibitor peptide; derived from p16
Molecular Weight:	2123.44

View Full Technical Details for [Ala⁹²]-p16 (84-103)

Technical Data
Citations

Biological Activity for [Ala⁹²]-p16 (84-103)

[Ala⁹²]-p16 (84-103) is a peptide derived from the tumor suppressor protein p16; inhibits cyclin-dependent kinase-4 (cdk4)/cyclin D1 (IC₅₀ ~ 1.5 μM) and binds to cdk6.

Technical Data for [Ala⁹²]-p16 (84-103)

M. Wt	2123.44
Formula	C₉₃H₁₅₅N₃₁O₂₆
Single Letter Sequence	DAAREGFLATLVVLHRAGAR
Storage	Desiccate at -20°C
CAS Number	189064-08-2
PubChem ID	71308539
InChi Key	SRSWQMWUNOIPDH-QCDQIEFZSA-N
Smiles	[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for [Ala⁹²]-p16 (84-103)

References are publications that support the biological activity of the product.

Fahraeus Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule. Oncogene 1998 PMID: 9482104

Product Documents for [Ala⁹²]-p16 (84-103)

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

[Ala⁹²]-p16 (84-103)

Tocris Bioscience, part of Bio-Techne | Catalog # 1902

Key Product Details

Biological Activity for [Ala⁹²]-p16 (84-103)

Technical Data for [Ala⁹²]-p16 (84-103)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Ala⁹²]-p16 (84-103)

Product Documents for [Ala⁹²]-p16 (84-103)

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected

[Ala92]-p16 (84-103)

Tocris Bioscience, part of Bio-Techne | Catalog # 1902

Key Product Details

Biological Activity for [Ala92]-p16 (84-103)

Technical Data for [Ala92]-p16 (84-103)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Ala92]-p16 (84-103)

Product Documents for [Ala92]-p16 (84-103)

COA

Certificate of Analysis

SDS

[Ala⁹²]-p16 (84-103)

Biological Activity for [Ala⁹²]-p16 (84-103)

Technical Data for [Ala⁹²]-p16 (84-103)

References for [Ala⁹²]-p16 (84-103)

Product Documents for [Ala⁹²]-p16 (84-103)