ACPT-II

Name: ACPT-II
Brand: Tocris Bioscience
SKU: 1112

Tocris Bioscience, part of Bio-Techne | Catalog # 1112

Citations (7)

COA / SDS

Competitive mGlu receptor antagonist

Discontinued Product

1112 has been discontinued. View all Non-selective mGluR Antagonists products.

Key Product Details

Description:	Competitive mGlu receptor antagonist
Chemical Name:	(1R,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid
Molecular Weight:	217.18

View Full Technical Details for ACPT-II

Technical Data
Citations

Biological Activity for ACPT-II

ACPT-II is a competitive metabotropic receptor antagonist (K_B values are 115, 88 and 77 μM at mGlu_1a, mGlu₂ and mGlu_4a respectively).

Licensing Information

Sold with the permission of the CNRS

Technical Data for ACPT-II

M. Wt	217.18
Formula	C₈H₁₁NO₆
Storage	Desiccate at -20°C
CAS Number	195209-04-2
PubChem ID	6604820
InChi Key	FERIKTBTNCSGJS-OBLUMXEWSA-N
Smiles	N[C@]1([C@@](O)=O)C[C@H]([C@](O)=O)[C@H]([C@@](O)=O)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ACPT-II

References are publications that support the biological activity of the product.

Bessis Closure of the venus flytrap model of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists. Proc.Natl.Acad.Sci.U.S.A. 2002 PMID: 12151600
Acher Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes. J.Med.Chem. 1997 PMID: 9301676