α-Cyclodextrin

Name: α-Cyclodextrin
Brand: Tocris Bioscience
SKU: 3180

Tocris Bioscience, part of Bio-Techne | Catalog # 3180

Citations (1)

COA / SDS

Cyclic complexing agent

Key Product Details

Description:	Cyclic complexing agent
Purity:	≥98% (HPLC)
Molecular Weight:	972.85

View Full Technical Details for α-Cyclodextrin

Technical Data
Citations

Biological Activity for α-Cyclodextrin

α-Cyclodextrin (α-CD) is a cylindrical oligosaccharide presenting a hydrophilic surface and a lipophilic cavity. α-Cyclodextrin can form inclusion complexes with a diverse range of hydrophobic compounds. These complexes increase the aqueous solubility, dissolution rate, and bioavailability of the guest compounds.

Technical Data for α-Cyclodextrin

M. Wt	972.85
Formula	C₃₆H₆₀O₃₀
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	10016-20-3
PubChem ID	444913
InChi Key	HFHDHCJBZVLPGP-RWMJIURBSA-N
Smiles	C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for α-Cyclodextrin

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	97.28	100
	water	97.28	100

Preparing Stock Solutions for α-Cyclodextrin

The following data is based on the product molecular weight 972.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.03 mL	5.14 mL	10.28 mL
5 mM	0.21 mL	1.03 mL	2.06 mL
10 mM	0.10 mL	0.51 mL	1.03 mL
50 mM	0.02 mL	0.10 mL	0.21 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

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References for α-Cyclodextrin

References are publications that support the biological activity of the product.

Rodriguez-Aller New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance. Eur.J.Pharm.Biopharm. 2015 PMID: 25960331