9-AC

Name: 9-AC
Brand: tocris
SKU: 0963

Catalog # 0963

Citations (2)

Datasheet / COA / SDS

Discontinued Product

0963 has been discontinued. View all Other Chloride Channel Compounds products.

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Bio-Techne Corporation

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Key Product Details

Description:	Chloride transport inhibitor
Chemical Name:	9-Anthracenecarboxylic acid
Purity:	≥99% (HPLC)
Molecular Weight:	222.24

View Full Technical Details for 9-AC

Biological Activity

9-AC is a Cl^- transport inhibitor with a moderate to strong inhibitory action on PKA activated cardiac I_cI.

Technical Data

M. Wt	222.24
Formula	C₁₅H₁₀O₂
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	723-62-6
PubChem ID	2201
InChi Key	XGWFJBFNAQHLEF-UHFFFAOYSA-N
Smiles	OC(=O)C1=C2C=CC=CC2=CC2=CC=CC=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mM
Solubility
	ethanol	10
	DMSO	100

Preparing Stock Solutions

The following data is based on the product molecular weight 222.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.50 mL	22.50 mL	45.00 mL
5 mM	0.90 mL	4.50 mL	9.00 mL
10 mM	0.45 mL	2.25 mL	4.50 mL
50 mM	0.09 mL	0.45 mL	0.90 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Cabantchik and Greger Chemical probes for anion transporters of mammalian cell membranes. Am.J.Physiol. 1992 PMID: 1566811
Gadsby The CFTR chloride channel of mammalian heart. Annu.Rev.Physiol. 1995 PMID: 7539989
Pusch Channel or transporter? The CLC saga continues. Exp.Physiol. 2006 PMID: 16179405
Estévez Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1. Neuron 2003 PMID: 12691663

Citations (2)

Showing 1 - 2 of 2 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for 9-AC include:

Freeman et al. (2013) Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors. Online J Biol Sci. 110:103
PMID: 23576702
Li et al. (2005) Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother. 49:388
PMID: 15616319

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Product Documents

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.

9-AC

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Technical Data

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Reconstitution Calculator

References

Citations (2)

Product Documents

COA

Certificate of Analysis

SDS

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