4-PPBP maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 0620
Specific σ ligand, NMDA antagonist
Discontinued Product
0620 has been discontinued.
View all General Sigma Receptor Ligands products.
Key Product Details
Description
Specific σ ligand, NMDA antagonist
Product Description
4-PPBP maleate is a σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.Product Specifications
Molecular Weight
409.52
Formula
C21H27N.C4H4O4
Storage
Store at RT
Purity
≥99% (HPLC)
Chemical Name
4-Phenyl-1-(4-phenylbutyl)piperidine maleate
CAS Number
201216-39-9
PubChem ID
11682970
InChI Key
OASPNIMFGJVLES-BTJKTKAUSA-N
SMILES
OC(=O)\C=C/C(O)=O.C(CCC1=CC=CC=C1)CN1CCC(CC1)C1=CC=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 10.24 | 25 | |
| Ethanol | 10.24 | 25 |
Preparing Stock Solutions
for 4-PPBP maleate
The following data is based on the product molecular weight 409.52
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 9.77 mL | 48.84 mL | 97.68 mL |
| 1.25 mM | 1.95 mL | 9.77 mL | 19.54 mL |
| 2.5 mM | 0.98 mL | 4.88 mL | 9.77 mL |
| 12.5 mM | 0.20 mL | 0.98 mL | 1.95 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Whittemore Antagonism of N-MthD.-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 1997 PMID: 9223571
- Glennon Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 1991 PMID: 1662725
Product Specific Notices for 4-PPBP maleate
For research use only
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