2-TEDC
Tocris Bioscience, part of Bio-Techne | Catalog # 0645
5-, 12-, 15-Lipoxygenase inhibitor
Discontinued Product
0645 has been discontinued.
View all Lipoxygenase Inhibitors products.
Key Product Details
Description
5-, 12-, 15-Lipoxygenase inhibitor
Product Description
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).Product Specifications
Molecular Weight
315.34
Formula
C16H13NO4S
Storage
Desiccate at +4°C
Purity
≥99% (HPLC)
Chemical Name
2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
CAS Number
132465-10-2
PubChem ID
6069552
InChI Key
KCGLTUBCAGZLHP-XYOKQWHBSA-N
SMILES
OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 100 | ||
| Ethanol | 25 |
Preparing Stock Solutions
for 2-TEDC
The following data is based on the product molecular weight 315.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.17 mL | 15.86 mL | 31.71 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.34 mL |
| 10 mM | 0.32 mL | 1.59 mL | 3.17 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.63 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Cho Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 1991 PMID: 2016727
Product Specific Notices for 2-TEDC
For research use only
Loading...
Loading...