2-TEDC

Name: 2-TEDC
Brand: tocris
SKU: 0645

Catalog # 0645

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

tel: (612) 379-2956

tel: (800) 343-7475 (free phone)

customercare.na@bio-techne.com

Shipping Information

$35 to United States

Products in stock will be shipped in 1-3 business days unless specified.

View Distributors

Key Product Details

Description:	5-, 12-, 15-Lipoxygenase inhibitor
Chemical Name:	2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate
Purity:	≥99% (HPLC)

View Full Technical Details for 2-TEDC

Biological Activity

Potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC₅₀ values are 0.09, 0.013 and 0.5 μM respectively).

Technical Data

M. Wt	315.34
Formula	C₁₆H₁₃NO₄S
Storage	Desiccate at +4°C
Purity	≥99% (HPLC)
CAS Number	132465-10-2
PubChem ID	6069552
InChi Key	KCGLTUBCAGZLHP-XYOKQWHBSA-N
Smiles	OC1=C(O)C=C(\C=C(/C#N)C(=O)OCCC2=CC=CS2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mM
Solubility
	DMSO	100
	ethanol	25

Preparing Stock Solutions

The following data is based on the product molecular weight 315.34.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.17 mL	15.86 mL	31.71 mL
5 mM	0.63 mL	3.17 mL	6.34 mL
10 mM	0.32 mL	1.59 mL	3.17 mL
50 mM	0.06 mL	0.32 mL	0.63 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Cho Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 1991 PMID: 2016727