2-Methyl-5-hydroxytryptamine hydrochloride

Name: 2-Methyl-5-hydroxytryptamine hydrochloride
Brand: Tocris Bioscience
SKU: 0558

Tocris Bioscience a Bio-Techne Brand

Catalog # 0558

COA / SDS

Discontinued Product

0558 has been discontinued. View all 5-HT3 Receptor Agonists products.

Key Product Details

Description:	5-HT₃ agonist/potent 5-HT₆ ligand
Purity:	≥98% (HPLC)
Molecular Weight:	226.71

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Biological Activity for 2-Methyl-5-hydroxytryptamine hydrochloride

5-HT₃ agonist (K_i = 1200 nM) and potent 5-HT₆ ligand (K_i = 46 nM).

Technical Data for 2-Methyl-5-hydroxytryptamine hydrochloride

M. Wt	226.71
Formula	C₁₁H₁₄N₂O.HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	845861-49-6
PubChem ID	11492320
InChi Key	ZNVRHQPXSBWLQP-UHFFFAOYSA-N
Smiles	Cl.CC1=C(CCN)C2=CC(O)=CC=C2N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for 2-Methyl-5-hydroxytryptamine hydrochloride

Solubility

Soluble Soluble to 100 mM in water

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References for 2-Methyl-5-hydroxytryptamine hydrochloride

References are publications that support the biological activity of the product.

Glennon 2-substituted tryptamines: agents with selectivity for 5-HT₆ serotonin receptors. J.Med.Chem. 2000 PMID: 10715164
Craig 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT₃ and putative 5-HT₄ receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 2402303
Ismaiel 5-HT₁ and 5-HT₂ binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 1990 PMID: 2299641
Wilson 5-Hydroxytryptamine₃ receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 1990 PMID: 1968974

Citations for 2-Methyl-5-hydroxytryptamine hydrochloride

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