2-Methyl-5-hydroxytryptamine hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0558
5-HT3 agonist/potent 5-HT6 ligand
Discontinued Product
0558 has been discontinued.
View all 5-HT3 Receptor Agonists products.
Key Product Details
Description
5-HT3 agonist/potent 5-HT6 ligand
Product Description
5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM).Product Specifications
Molecular Weight
226.71
Formula
C11H14N2O.HCl
Storage
Store at RT
Purity
≥98% (HPLC)
CAS Number
845861-49-6
PubChem ID
11492320
InChI Key
ZNVRHQPXSBWLQP-UHFFFAOYSA-N
SMILES
Cl.CC1=C(CCN)C2=CC(O)=CC=C2N1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 22.67 | 100 |
Preparing Stock Solutions
for 2-Methyl-5-hydroxytryptamine hydrochloride
The following data is based on the product molecular weight 226.71
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.41 mL | 22.05 mL | 44.11 mL |
| 5 mM | 0.88 mL | 4.41 mL | 8.82 mL |
| 10 mM | 0.44 mL | 2.21 mL | 4.41 mL |
| 50 mM | 0.09 mL | 0.44 mL | 0.88 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Wilson 5-Hydroxytryptamine3 receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 1990 PMID: 1968974
- Glennon 2-substituted tryptamines: agents with selectivity for 5-HT6 serotonin receptors. J.Med.Chem. 2000 PMID: 10715164
- Ismaiel 5-HT1 and 5-HT2 binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 1990 PMID: 2299641
- Craig 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 2402303
Product Specific Notices for 2-Methyl-5-hydroxytryptamine hydrochloride
For research use only
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