1-Methylpsilocin

Name: 1-Methylpsilocin
Brand: Tocris Bioscience
SKU: 3017

Tocris Bioscience, part of Bio-Techne | Catalog # 3017

Citations (2)

COA / SDS

Potent and selective 5-HT2C agonist

Discontinued Product

3017 has been discontinued. View all 5-HT2C Receptor Agonists products.

Key Product Details

Description:	Potent and selective 5-HT_2C agonist
Chemical Name:	3-[2-(Dimethylamino)ethyl]-1-methylindol-4-ol
Purity:	≥99% (HPLC)
Molecular Weight:	218.29

View Full Technical Details for 1-Methylpsilocin

Technical Data
Citations

Biological Activity for 1-Methylpsilocin

1-Methylpsilocin is a potent and selective 5-HT_2C agonist (IC₅₀ values are 12 and 633 nM for 5-HT_2C and 5-HT_2A receptors respectively). Displays high affinity for the 5-HT_2B receptor (K_i = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.

Technical Data for 1-Methylpsilocin

M. Wt	218.29
Formula	C₁₃H₁₈N₂O
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	1465-16-3
PubChem ID	44404883
InChi Key	MZZRFEIDRWKTKJ-UHFFFAOYSA-N
Smiles	OC1=C2C(N(C)C=C2CCN(C)C)=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for 1-Methylpsilocin

References are publications that support the biological activity of the product.

Sard SAR of psilocybin analogs: discovery of a selective 5-HT_2C agonist. Bioorg.Med.Chem.Letts.

1-Methylpsilocin

Tocris Bioscience, part of Bio-Techne | Catalog # 3017

Key Product Details

Biological Activity for 1-Methylpsilocin

Technical Data for 1-Methylpsilocin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for 1-Methylpsilocin

Product Documents for 1-Methylpsilocin

COA

Certificate of Analysis

SDS

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