Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge New
ProteinSimple, part of Bio-Techne | Catalog # SPCKB-NP-016629
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Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.
Key Product Details
Assay Length
Sample Type & Volume Required Per Well*
Sensitivity
Assay Range
Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge Summary
*The Sample Volume represented is based on the amount of sample incorporated into the reaction after taking into account the assay's minimum required dilution for a given matrix. Serial dilution may be necessary to achieve some of the final sample volumes represented.
Compatible Instruments
Ella Automated Immunoassay System
Product Specifications
Assay Type
Format
Reactivity
Specificity
Cross-reactivity
Interference
Precision
Intra-Assay Precision (Precision within an assay) Each control was tested multiple times in one CHI3L1 assay.
Inter-Assay Precision (Precision between assays) Replicates of each CHI3L1 control were tested in multiple assays performed by at least three technicians using two lots of reagents for non-human primate CHI3L1.
Cell Culture Supernates, Cerebrospinal Fluid, EDTA Plasma, Heparin Plasma, Serum
| Intra-Assay Precision | Inter-Assay Precision | |||
|---|---|---|---|---|
| Sample | 1 | 2 | 1 | 2 |
| n | 16 | 16 | 18 | 17 |
| Mean (pg/mL) | 217 | 11535 | 205 | 11411 |
| Standard Deviation | 8.91 | 328 | 16.0 | 675 |
| CV% | 4.1 | 2.8 | 7.8 | 5.9 |
Recovery for Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge
Recovery for the non-human primate CHI3L1 assays was evaluated at three different spiked concentrations of CHI3L1 protein.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| Cell Culture Media (n=2) | 81 | 76-86 |
Linearity
Samples containing and/or spiked with high concentrations of CHI3L1 were serially diluted with Sample Diluent to produce samples within the dynamic range of the assay.
Scientific Data Images for Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge
Simple Plex Non-Human Primate CHI3L1 Assay Standard Curve
Data shown represents typical performance results for Lower Limit of Quantitation (LLOQ) and Upper Limit of Quantitation (ULOQ) for Simple Plex Non-Human Primate CHI3L1 Assay. Assay range is 6.68-25,500 pg/mL.Preparation and Storage
Shipping
Stability & Storage
Background: Chitinase 3-like 1/YKL-40
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells. CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Alternate Names
Gene Symbol
Additional Chitinase 3-like 1/YKL-40 Products
- All Products for Chitinase 3-like 1/YKL-40
- Chitinase 3-like 1/YKL-40 cDNA Clones
- Chitinase 3-like 1/YKL-40 ELISA Kits
- Chitinase 3-like 1/YKL-40 Luminex Assays
- Chitinase 3-like 1/YKL-40 Lysates
- Chitinase 3-like 1/YKL-40 Primary Antibodies
- Chitinase 3-like 1/YKL-40 Proteins and Enzymes
- Chitinase 3-like 1/YKL-40 Simple Plex
Product Documents for Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge
Product Specific Notices for Simple Plex Non-Human Primate Chitinase 3-like 1 Cartridge
For research use only