Simple Plex Control for Mouse/Rat Angiopoietin-2
ProteinSimple, part of Bio-Techne | Catalog # 896173
Control for use with Mouse/Rat Angiopoietin-2 Simple Plex Cartridge Kit
Key Product Details
Species
Mouse, Rat
Applications
Control, Simple Plex Automated Immunoassay
Product Summary for Simple Plex Control for Mouse/Rat Angiopoietin-2
INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of mouse/rat Angiopoietin-2 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Angiopoietin-2
Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that regulates vascular remodeling by promoting endothelial cell survival, proliferation, and migration and destabilizing the interaction between EC and perivascular cells. Ang-2 is required for postnatal vascular remodeling, and it cooperates with Ang-1 during lymphatic vessel development. It mediates the upregulation of ICAM-1 and VCAM-1 on EC, which facilitates the adhesion of leukocytes during inflammation. Its direct interaction with Integrins promotes tumor cell invasion. Ang-2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It associates into dimers, trimers, and larger multimers and binds the receptor Tie-2, with its function as an agonist or antagonist depending on its state of multimerization.
Alternate Names
ANGPT2
Entrez Gene IDs
Gene Symbol
ANGPT2
Additional Angiopoietin-2 Products
Product Documents for Simple Plex Control for Mouse/Rat Angiopoietin-2
Product Specific Notices for Simple Plex Control for Mouse/Rat Angiopoietin-2
For research use only
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