Simple Plex Control for Human VEGFR2/KDR/Flk-1

Name: Simple Plex Control for Human VEGFR2/KDR/Flk-1
Brand: ProteinSimple
SKU: 898064

ProteinSimple, part of Bio-Techne | Catalog # 898064

Product Datasheet / COA

Control for Human VEGFR2/KDR/Flk-1 Simple Plex Cartridge Kit

Key Product Details

Technical Data
Citations

Summary for Simple Plex Control for Human VEGFR2/KDR/Flk-1

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human VEGFR2/KDR/Flk-1 concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Product Specifications for Simple Plex Control for Human VEGFR2/KDR/Flk-1

Species	Human
Applications	Control, Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: VEGFR2/KDR/Flk-1

Item	Value
Long Name	Vascular Endothelial Growth Factor Receptor 2
Entrez Gene IDs	3791 (Human); 16542 (Mouse)
Alternate Names	CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, FLK1tyrosine kinase growth factor receptor, Fetal liver kinase 1, Flk-1, Flk1, KDR, KRD1, Kinase insert domain receptor, Ly73, Protein-tyrosine kinase receptor flk-1, VEGF R2, VEGFR, VEGFR-2, VEGFR2, fetal liver kinase-1, kinase insert domain receptor (a type III receptor tyrosine kinase), soluble VEGFR2, vascular endothelial growth factor receptor 2

Product Documents for Simple Plex Control for Human VEGFR2/KDR/Flk-1

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