Simple Plex Control for Human Lipocalin-2/NGAL
ProteinSimple, part of Bio-Techne | Catalog # 898097
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Product Summary for Simple Plex Control for Human Lipocalin-2/NGAL
Formulation, Preparation, and Storage
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Storage
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.
Background: Lipocalin-2/NGAL
Lipocalin-2/NGAL (Neutrophil Gelatinase-associated Lipocalin) is a secreted carrier protein that acts in the innate immune response, differentiation, tumorigenesis, and cell survival. It is induced in macrophages, glial cells, and epithelial cells during inflammation, anemia, and hypoxia. Lipocalin-2 binds catecholate siderophores which are secreted by bacteria and are required for bacterial iron uptake. Lipocalin-2 functions as a bacteriostatic agent in the innate immune response by limiting the bacterial iron supply. Iron uptake by Lipocalin-2 into mammalian cells is important for the regulation of iron-sensitive gene transcription. In the kidney, Lipocalin-2-mediated iron trafficking is required for protection from renal injury.
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Additional Lipocalin-2/NGAL Products
Product Documents for Simple Plex Control for Human Lipocalin-2/NGAL
Product Specific Notices for Simple Plex Control for Human Lipocalin-2/NGAL
For research use only