Simple Plex Control for Human alpha 2-Macroglobulin

Name: Simple Plex Control for Human alpha 2-Macroglobulin
Brand: ProteinSimple
SKU: 897116

ProteinSimple, part of Bio-Techne | Catalog # 897116

Product Datasheet / COA

Control for use with Human alpha 2-Macroglobulin Simple Plex Assay Cartridge Kit

Summary for Simple Plex Control for Human alpha 2-Macroglobulin

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of Human alpha 2-Macroglobulin concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Alpha 2-Macroglobulin (A2M) is an abundant plasma glycoprotein that has structural similarity to other A2M family members including complement components C3, C4 and C5. A2M is a tetramer (720-kDa) of 4 identical subunits (180-kDa) formed by two disulfide bond-linked dimers. It is a general and irreversible protease inhibitor capable of inhibiting all four classes of proteases by a unique trapping mechanism. A2M also binds many cytokines and growth factors. In the brain, A2M binds soluble beta Amyloid. A2M is recognized as a late onset Alzheimers disease gene.

Product Specifications for Simple Plex Control for Human alpha 2-Macroglobulin

Species	Human
Applications	Simple Plex Automated Immunoassay
Source	N/A

Preparation & Storage

Shipping Conditions

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: alpha 2-Macroglobulin

Item	Value
Entrez Gene IDs	2 (Human)
Alternate Names	A2M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, CPAMD5, CPAMD5DKFZp779B086, FWP007, S863-7, alpha 2-Macroglobulin, alpha 2Macroglobulin, alpha-2-M, alpha-2-macroglobulin

Product Documents for Simple Plex Control for Human alpha 2-Macroglobulin

Product Datasheets

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