Pretreatment K Buffer

INTENDED USE AND DESCRIPTION: For use a pretreatment buffer to enhance protein extraction for the determination of HIV p24 concentrations in biological samples. Pretreatment K buffer is provided in a 10 mL liquid state. Please refer to the lot specific certificate of analysis and Simple Plex HIV p24 2^nd Generation Cartridge product insert for additional information.
 

The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55^Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins which are required for virus particle assembly. p24 is a major viral core structural protein. Its measurement is commonly used as an indicator of HIV-1 infection and viral load.