Recombinant Mouse IL-23 Protein Best Seller
Catalog # 1887-ML | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Accession #
Source
Conjugate
Applications
Product Specifications
Source
Mouse IL-23 p40 (Met23-Ser335) Accession # P43432 |
IGSGSSRGGSGSGGSGGGGSK | Mouse IL-23 p19 (Leu20-Ala196) Accession # Q9EQ14 |
N-terminus | C-terminus |
Purity
Endotoxin Level
N-terminal Sequence Analysis
Predicted Molecular Mass
SDS-PAGE
Activity
The ED50 for this effect is 0.05-0.25 ng/mL.
Scientific Data Images for Recombinant Mouse IL-23 Protein
Recombinant Mouse IL‑23 Protein SEC-MALS.
Recombinant Mouse IL-23 (Catalog # 1887-ML) has a molecular weight (MW) of 60.4 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Formulation, Preparation and Storage
Carrier Free
What does CF mean?CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
Carrier: 1887-ML
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Carrier Free: 1887-ML/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 100 μg/mL in sterile PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Background: IL-23
References
- Oppmann, B. et al. (2000) Immunity 13:715.
- Lankford, C.S. and D.M. Frucht (2003) J. Leukoc. Biol. 73:49.
- Parham, C. et al. (2002) J. Immunol. 168:5699.
- Belladonna, M.L. et al. (2002) J. Immunol. 168:5448.
- Aggarwal, S. et al. (2003) J. Biol. Chem. 278:1910.
Long Name
Alternate Names
Gene Symbol
UniProt
Product Documents for Recombinant Mouse IL-23 Protein
Product Specific Notices for Recombinant Mouse IL-23 Protein
For research use only
Citations for Recombinant Mouse IL-23 Protein (180)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Mouse IL-23 Protein include:
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Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGao et al. (2023-07-13), Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system Nature immunology
PMID: 37443284 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWL Yang et al. (2023-02-16), Nsun2 coupling with RoRgammat shapes the fate of Th17 cells and promotes colitis Nature Communications, 2023-014(1):863.
PMID: 36792629 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT Huu Hoang et al. (2022-09-28), Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms Science Advances, 2022-08(39):eabo5525.
PMID: 36170363 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Rani et al. (2022-09-26), IL-3 regulates the differentiation of pathogenic Th17 cells European Journal of Immunology, 2022-00(0).
PMID: 36074916 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoN Millet et al. (2022-09-22), IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis Nature Communications, 2022-013(1):5545.
PMID: 36138043 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Nishida-Ta et al. (2022-07-29), Antioxidative enzyme NAD(P)H quinone oxidoreductase 1 (NQO1) modulates the differentiation of Th17 cells by regulating ROS levels PLoS ONE, 2022-017(7):e0272090.
PMID: 35905076 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Chen et al. (2022-06-06), pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells Nature Immunology, 2022-00(0).
PMID: 35668320 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYS Zhang et al. (2022-05-25), Acetylation licenses Th1 cell polarization to constrain Listeria monocytogenes infection Cell Death and Differentiation, 2022-00(0).
PMID: 35614130 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLEA Damasceno et al. (2022-05-24), STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program Cell Reports, 2022-039(8):110838.
PMID: 35613599 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Zhang et al. (2022-05-03), TH17 cells promote CNS inflammation by sensing danger signals via Mincle Nature Communications, 2022-013(1):2406.
PMID: 35504893 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHW Cheng et al. (2022-04-19), Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function Nature Communications, 2022-013(1):2027.
PMID: 35440118 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayN Yogev et al. (2022-03-29), CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T�cell survival Cell Reports, 2022-038(13):110565.
PMID: 35354043 -
Species: Mouse
Sample Types: Organoid
Applications: Organoid CultureM Wakai et al. (2022-03-18), Promoting mechanism of serum amyloid a family expression in mouse intestinal epithelial cells PLoS ONE, 2022-017(3):e0264836.
PMID: 35303008 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureS Ma et al. (2022-03-15), RORgammat phosphorylation protects against T�cell-mediated inflammation Cell Reports, 2022-038(11):110520.
PMID: 35294872 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayV Patel et al. (2021-12-23), Epigenetic drug ameliorated type 1 diabetes via decreased generation of Th1 and Th17 subsets and restoration of self-tolerance in CD4+ T cells International immunopharmacology, 2021-1103(0):108490.
PMID: 34954557 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayY Zhu et al. (2021-12-22), Allosteric inhibition of SHP2 uncovers aberrant TLR7 trafficking in aggravating psoriasis Embo Molecular Medicine, 2021-10(0):e14455.
PMID: 34936223 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Gurusamy et al. (2021-11-23), G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators Nature Communications, 2021-112(1):6798.
PMID: 34815397 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayX Chi et al. (2021-09-14), RORalpha is critical for mTORC1 activity in T�cell-mediated colitis Cell Reports, 2021-036(11):109682.
PMID: 34525365 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Agasing et al. (2021-08-20), Interferon-beta Intensifies Interleukin-23-Driven Pathogenicity of T Helper Cells in Neuroinflammatory Disease Cells, 2021-010(8).
PMID: 34440908 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Zhou et al. (2021-06-16), m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity Science Advances, 2021-07(25).
PMID: 34134995 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayELY Chen et al. (2021-06-08), Ontogenic timing, T�cell receptor signal strength, and Notch signaling direct &gamma&delta T�cell functional differentiation in�vivo Cell Reports, 2021-035(10):109227.
PMID: 34107257 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFRC Costa et al. (2021-05-25), NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes Cell Reports, 2021-035(8):109176.
PMID: 34038731 -
Species: Mouse
Sample Types: In Vivo
Applications: BioassayH Tao et al. (2021-04-01), Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals Nature Communications, 2021-012(1):2029.
PMID: 33795689 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Maria et al. (2021-03-13), Pertussis Toxin Inhibits Encephalitogenic T-Cell Infiltration and Promotes a B-Cell-Driven Disease during Th17-EAE International Journal of Molecular Sciences, 2021-022(6).
PMID: 33805762 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPMIA Doss et al. (2021-03-09), Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity Cell Reports, 2021-034(10):108833.
PMID: 33691111 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayR Yabe et al. (2021-01-04), TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens Nature Communications, 2021-012(1):94.
PMID: 33397982 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayA Baniahmad et al. (2020-11-24), The frequency of follicular T helper cells differs in acute and chronic neuroinflammation Sci Rep, 2020-110(1):20485.
PMID: 33235306 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureH Zhang et al. (2020-11-24), An IL-27-Driven Transcriptional Network Identifies Regulators of IL-10 Expression across T Helper Cell Subsets Cell Rep, 2020-133(8):108433.
PMID: 33238123 -
Species: Mouse
Sample Types: Organoid
Applications: BioassayR Kajino-Sak et al. (2020-11-12), Synthetic lethality between MyD88 loss and mutations in Wnt/&beta-catenin pathway in intestinal tumor epithelial cells Oncogene, 2020-10(0).
PMID: 33177648 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayI Mizoguchi et al. (2020-11-02), EBV-induced gene 3 augments IL-23R&alpha protein expression through a chaperone calnexin J. Clin. Invest., 2020-10(0).
PMID: 32809973 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Liu et al. (2020-06-22), ADAM12 is a costimulatory molecule that determines Th1 cell fate and mediates tissue inflammation Cell. Mol. Immunol., 2020-00(0).
PMID: 32572163 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAM Agasing et al. (2020-06-05), Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica Nat Commun, 2020-011(1):2856.
PMID: 32503977 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKM Lee et al. (2020-05-29), IL-23 in arthritic and inflammatory pain development in mice Arthritis Res. Ther., 2020-022(1):123.
PMID: 32471485 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayP Mamareli et al. (2020-04-30), Targeting cellular fatty acid synthesis limits T helper and innate lymphoid cell function during intestinal inflammation and infection Mucosal Immunol, 2020-00(0).
PMID: 32355319 -
Species: Mouse
Sample Types: Dendritic Cells
Applications: BioassayAE Morelli et al. (2020-03-10), Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells Cell Rep, 2020-030(10):3448-3465.e8.
PMID: 32160549 -
Applications: ELISA DevelopmetD Liu et al. (2020-03-04), Prognostic value of serum soluble interleukin-23 receptor and related T-helper 17 cell cytokines in non-small cell lung carcinoma Cancer Sci., 2020-0111(4):1093-1102.
PMID: 32020720 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureA Singh et al. (2020-02-28), Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells Sci Rep, 2020-010(1):3766.
PMID: 32111885 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureI Raphael et al. (2019-12-19), TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells JCI Insight, 2019-14(24).
PMID: 31852844 -
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: BioassayW Razawy et al. (2019-11-28), CD4+ CCR6+ T�cells, but not gammadelta T�cells, are important for the IL-23R-dependent progression of antigen-induced inflammatory arthritis in mice Eur. J. Immunol., 2019-150(2):245-255.
PMID: 31778214 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureHG Lee et al. (2019-10-23), NFAT-Specific Inhibition by dNP2-VIVITAmeliorates Autoimmune Encephalomyelitisby Regulation of Th1 and Th17 Mol Ther Methods Clin Dev, 2019-116(0):32-41.
PMID: 31737742 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Radulovic et al. (2019-05-31), NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death J. Immunol., 2019-00(0).
PMID: 31152078 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJZ Kawalkowsk et al. (2019-05-01), cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs Sci Adv, 2019-05(5):eaaw5422.
PMID: 31049403 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Abdullah et al. (2019-04-26), Activation of aryl hydrocarbon receptor signaling by a novel agonist ameliorates autoimmune encephalomyelitis PLoS ONE, 2019-014(4):e0215981.
PMID: 31026283 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Okunuki et al. (2019-04-25), Retinal microglia initiate neuroinflammation in ocular autoimmunity Proc. Natl. Acad. Sci. U.S.A., 2019-00(0).
PMID: 31023885 -
Species: Mouse
Sample Types: Organoids
Applications: BioassayH Katsura et al. (2019-03-28), IL-1 and TNF? Contribute to the Inflammatory Niche to Enhance Alveolar Regeneration Stem Cell Reports, 2019-00(0).
PMID: 30930244 -
Species: Mouse
Sample Types: Whole Cells
Y Liu et al. (2019-03-01), NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development EBioMedicine, 2019-00(0).
PMID: 30827928 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHG Lee et al. (2019-02-12), Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis Nat Commun, 2019-010(1):709.
PMID: 30755603 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKL Graham et al. (2019-02-04), DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis Proc. Natl. Acad. Sci. U.S.A., 2019-00(0).
PMID: 30718413 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayK Yasuda et al. (2019-02-01), Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation Nat Commun, 2019-010(1):549.
PMID: 30710091 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayM Amir et al. (2018-12-26), REV-ERB? Regulates TH17 Cell Development and Autoimmunity Cell Rep, 2018-125(13):3733-3749.e8.
PMID: 30590045 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKA de Lima et al. (2018-11-13), TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism Cell Death Dis, 2018-19(11):1130.
PMID: 30425241 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCJ Zhang et al. (2018-10-29), TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation J. Clin. Invest., 2018-10(0).
PMID: 30372424 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCN Berger et al. (2018-10-26), The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses PLoS Pathog., 2018-114(10):e1007406.
PMID: 30365535 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAO Bamidele et al. (2018-09-14), Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation Cell Mol Gastroenterol Hepatol, 2018-07(1):55-71.
PMID: 30510991 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHC Chuang et al. (2018-09-12), GLK-IKK? signaling induces dimerization and translocation of the AhR-ROR?t complex in IL-17A induction and autoimmune disease Sci Adv, 2018-04(9):eaat5401.
PMID: 30214937 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Breuer et al. (2018-08-22), Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus J Neuroinflammation, 2018-015(1):236.
PMID: 30134924 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Bouchareyc et al. (2018-05-15), ??TCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis Sci Rep, 2018-08(1):7590.
PMID: 29765156 -
Species: Mouse
Sample Types: Whole Tissue
Applications: BioassayVL Ngo et al. (2018-05-14), A cytokine network involving IL-36?, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage Proc. Natl. Acad. Sci. U.S.A., 2018-00(0).
PMID: 29760082 -
Species: Mouse
Sample Types: Whole Cells,In Vivo
Applications: In Vivo,BioassayR Wu et al. (2018-05-14), MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation J. Clin. Invest., 2018-00(0).
PMID: 29757188 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Mikami et al. (2018-04-16), NCR+ ILC3 maintain larger STAT4 reservoir via T-BET to regulate type 1 features upon IL-23 stimulation in mice Eur. J. Immunol., 2018-00(0).
PMID: 29524223 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Jiang et al. (2018-04-12), Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28 Nat Commun, 2018-09(1):1424.
PMID: 29651155 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Meyer Zu H et al. (2018-03-20), Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1 Immunity, 2018-048(3):556-569.e7.
PMID: 29562202 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Suto et al. (2018-03-06), IL-25 enhances Th17 cell-mediated contact dermatitis by promoting IL-1? production by dermal dendritic cells J. Allergy Clin. Immunol., 2018-00(0).
PMID: 29522843 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Hou et al. (2018-03-05), IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis Protein Cell, 2018-00(0).
PMID: 29508278 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayB Sun et al. (2018-03-05), Characterization and allergic role of IL-33-induced neutrophil polarization Cell. Mol. Immunol., 2018-00(0).
PMID: 29503441 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAJ St Leger et al. (2018-02-28), STAT-3-independent production of IL-17 by mouse innate-like ?? T cells controls ocular infection J. Exp. Med., 2018-00(0).
PMID: 29490936 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJ Emgård et al. (2018-01-16), Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation Immunity, 2018-048(1):120-132.e8.
PMID: 29343433 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPC Duncker et al. (2017-12-29), GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction J. Immunol., 2017-10(0).
PMID: 29288202 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHA Purvis et al. (2017-10-20), Protein Tyrosine Phosphatase PTPN22 regulates IL-1? dependent Th17 responses by modulating dectin-1 signaling in mice Eur. J. Immunol., 2017-10(0).
PMID: 28948613 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayT He et al. (2017-09-11), Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis Oncotarget, 2017-08(57):96993-97008.
PMID: 29228588 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayA Muschaweck et al. (2017-08-30), IL-1? and IL-23 Promote Extrathymic Commitment of CD27(+)CD122(-) ?? T Cells to ??T17 Cells J. Immunol., 2017-00(0).
PMID: 28855314 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayY Arima et al. (2017-08-15), Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit Elife, 2017-06(0).
PMID: 28809157 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoAK Savage et al. (2017-07-26), The Development of Steady-State Activation Hubs between Adult LTi ILC3s and Primed Macrophages in Small Intestine J. Immunol., 2017-00(0).
PMID: 28747343 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayW Pan et al. (2017-07-21), The excretory-secretory products of Echinococcus granulosus protoscoleces directly regulate the differentiation of B10, B17 and Th17 cells Parasit Vectors, 2017-010(1):348.
PMID: 28732522 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWF Carson et al. (2017-07-21), The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages J. Immunol., 2017-00(0).
PMID: 28733487 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoA Aki et al. (2017-06-28), Hypomorphic A20 expression confers susceptibility to psoriasis PLoS ONE, 2017-012(6):e0180481.
PMID: 28658319 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Dai et al. (2017-06-23), IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus J. Immunol., 2017-00(0).
PMID: 28646040 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySH Kim et al. (2017-06-21), Microbiota-derived butyrate suppresses group 3 innate lymphoid cells in terminal ileal Peyer's patches Sci Rep, 2017-07(1):3980.
PMID: 28638068 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHP Thu Le et al. (2017-06-12), The frequency of Th17�cells in the small intestine exhibits a day-night variation dependent on circadian clock activity Biochem. Biophys. Res. Commun., 2017-00(0).
PMID: 28619514 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMM Montoya et al. (2017-06-12), A Distinct Inhibitory Function for miR-18a in Th17 Cell Differentiation J. Immunol., 2017-00(0).
PMID: 28607111 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayH Yang et al. (2017-05-26), Viral RNA-Unprimed Rig-I Restrains Stat3 Activation in the Modulation of Regulatory T Cell/Th17 Cell Balance J. Immunol., 2017-00(0).
PMID: 28550197 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayQ Zhao et al. (2017-05-24), Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota J. Immunol., 2017-00(0).
PMID: 28539431 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoH Zhu et al. (2017-05-01), RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease EMBO Mol Med, 2017-09(5):589-604.
PMID: 28377495 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCN Lino et al. (2017-04-24), Eomes expression reports the progressive differentiation of IFN-?-producing Th1-like ?? T cells Eur. J. Immunol., 2017-00(0).
PMID: 28386934 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayG Fu et al. (2017-04-11), Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1 J. Exp. Med., 2017-00(0).
PMID: 28400474 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayER Pierson et al. (2017-04-06), GM-CSF is not essential for experimental autoimmune encephalomyelitis but promotes brain-targeted disease JCI Insight, 2017-02(7):e92362.
PMID: 28405624 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayS Downs-Cann et al. (2017-03-14), Suppressive IL-17A(+)Foxp3(+) and ex-Th17 IL-17A(neg)Foxp3(+) Treg cells are a source of tumour-associated Treg cells Nat Commun, 2017-08(0):14649.
PMID: 28290453 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayL Franchi et al. (2017-02-27), Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis J. Immunol, 2017-00(0).
PMID: 28242647 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZ Hao et al. (2017-01-13), K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression Nat Commun, 2017-08(0):14003.
PMID: 28084302 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMA L‚cuyer et al. (2017-01-09), Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis Proc. Natl. Acad. Sci. U.S.A, 2017-0114(4):E524-E533.
PMID: 28069965 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAA Kesewa Lay et al. (2017-01-04), Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production Sci Rep, 2017-07(0):39649.
PMID: 28051111 -
Species: Mouse
Sample Types: Whole Cells,In Vivo
Applications: Bioassay,In Vivo(2016-12-01), Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis Sci Rep, 2016-16(0):37977.
PMID: 27905482 -
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo(2016-09-26), Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function Proc Natl Acad Sci USA, 2016-00(0).
PMID: 27671649 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-07-27), Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor Sci Rep, 2016-06(0):30384.
PMID: 27461849 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMarie-Laure Michel (2016-07-22), SLAM-associated protein favours the development of iNKT2 over iNKT17 cells Eur J Immunol, 2016-00(0).
PMID: 27338553 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLN Guthrie et al. (2016-05-23), Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses J. Biol. Chem., 2016-0291(30):15830-40.
PMID: 27226638 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-05-19), Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU) PLoS ONE, 2016-011(5):e0155953.
PMID: 27196432 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2016-04-22), Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells J Immunol, 2016-0196(11):4731-8.
PMID: 27183613 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCE O'Leary et al. (2016-04-18), Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells Nat Commun, 2016-07(0):11226.
PMID: 27088444 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCM Larabee et al. (2016-04-11), Myelin-specific Th17 cells induce severe relapsing optic neuritis with irreversible loss of retinal ganglion cells in C57BL/6 mice Mol Vis, 2016-022(0):332-41.
PMID: 27122964 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShweta Pasi (2016-03-28), Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response J Biol Chem, 2016-0291(23):12358-69.
PMID: 27022030 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChih-Chung Lin et al. (2016-02-01), IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. The Journal of Experimental Medicine, 2016-00(0):1540-9538.
PMID: 26834156 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLee J et al. (2016-02-01), RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis. J Neuroinflammation, 2016-013(1):24.
PMID: 26831924 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayVelazquez F et al. (2015-12-23), CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J Immunol, 2015-1196(3):1305-16.
PMID: 26700769 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBozoyan L et al. (2015-09-17), Interleukin-36gamma is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis. J Neuroinflammation, 2015-012(0):173.
PMID: 26377915 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDoisne J et al. (2015-09-14), Composition, Development, and Function of Uterine Innate Lymphoid Cells. J Immunol, 2015-0195(8):3937-45.
PMID: 26371244 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen M et al. (2015-07-06), An A2B Adenosine Receptor Agonist Promotes Th17 Autoimmune Responses in Experimental Autoimmune Uveitis (EAU) via Dendritic Cell Activation. PLoS ONE, 2015-010(7):e0132348.
PMID: 26147733 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLombes A et al. (2015-06-29), Adaptive Immune-like gamma/delta T Lymphocytes Share Many Common Features with Their alpha/beta T Cell Counterparts. J Immunol, 2015-0195(4):1449-58.
PMID: 26123353 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayRussi A et al. (2015-05-13), Cutting edge: c-Kit signaling differentially regulates type 2 innate lymphoid cell accumulation and susceptibility to central nervous system demyelination in male and female SJL mice. J Immunol, 2015-0194(12):5609-13.
PMID: 25972476 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKim Y et al. (2015-03-13), Regulation of autoimmune germinal center reactions in lupus-prone BXD2 mice by follicular helper T cells. PLoS ONE, 2015-010(3):e0120294.
PMID: 25768299 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassayde Andrade Pereira B et al. (2015-03-05), Tolerance of activated pathogenic CD4+ T cells by transcriptional targeting of dendritic cells. Gene Ther, 2015-022(5):382-90.
PMID: 25739989 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayOkamura T et al. (2015-02-19), TGF-beta3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses. Nat Commun, 2015-06(0):6329.
PMID: 25695838 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKlimatcheva E et al. (2015-02-12), CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol, 2015-016(0):6.
PMID: 25879435 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySchwinge D et al. (2015-02-11), Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis. J Immunol, 2015-0194(6):2522-30.
PMID: 25672751 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMunoz M et al. (2015-02-10), Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection. Immunity, 2015-042(2):321-31.
PMID: 25680273 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBasu R et al. (2015-02-02), IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol, 2015-016(3):286-95.
PMID: 25642823 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMonin L et al. (2015-01-28), Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge. Mucosal Immunol, 2015-08(5):1099-109.
PMID: 25627812 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAbadier M et al. (2015-01-23), Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier. Eur J Immunol, 2015-045(4):1043-58.
PMID: 25545837 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHaftmann C et al. (2015-01-22), miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. Eur J Immunol, 2015-045(4):1192-205.
PMID: 25486906 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHarada M et al. (2015-01-02), Temporal expression of growth factors triggered by epiregulin regulates inflammation development. J Immunol, 2015-0194(3):1039-46.
PMID: 25556244 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen J et al. (2014-10-15), Dysbiosis caused by vitamin D receptor deficiency confers colonization resistance to Citrobacter rodentium through modulation of innate lymphoid cells. Mucosal Immunol, 2014-18(3):618-26.
PMID: 25315967 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDunne A et al. (2014-10-15), A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. Mucosal Immunol, 2014-18(3):607-17.
PMID: 25315966 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGlenn J et al. (2014-10-01), Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis. Stem Cells, 2014-132(10):2744-55.
PMID: 24911892 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayNeumann C et al. (2014-07-29), Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med, 2014-0211(9):1807-19.
PMID: 25073792 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySchiering C et al. (2014-07-16), The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature, 2014-0513(7519):564-8.
PMID: 25043027 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayKnowlden S et al. (2014-07-08), Regulation of T cell motility in vitro and in vivo by LPA and LPA2. PLoS ONE, 2014-09(7):e101655.
PMID: 25003200 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMycko M et al. (2014-06-18), Brain glycolipids suppress T helper cells and inhibit autoimmune demyelination. J Neurosci, 2014-034(25):8646-58.
PMID: 24948818 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHou Y et al. (2014-06-06), The inhibitory effect of IFN-gamma on protease HTRA1 expression in rheumatoid arthritis. J Immunol, 2014-0193(1):130-8.
PMID: 24907345 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhu E et al. (2014-05-19), miR-20b suppresses Th17 differentiation and the pathogenesis of experimental autoimmune encephalomyelitis by targeting RORgammat and STAT3. J Immunol, 2014-0192(12):5599-609.
PMID: 24842756 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayReynolds C et al. (2014-05-09), Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile. BMC Biol, 2014-012(0):32.
PMID: 24886643 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYeste A et al. (2014-05-06), IL-21 induces IL-22 production in CD4+ T cells. Nat Commun, 2014-05(0):3753.
PMID: 24796415 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySriskantharajah S et al. (2014-03-17), Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase. J Immunol, 2014-0192(8):3518-29.
PMID: 24639351 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZhou H et al. (2014-03-07), Differential IL-10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction. Eur J Immunol, 2014-044(5):1352-62.
PMID: 24496948 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen Y et al. (2014-03-01), CD49a promotes T-cell-mediated hepatitis by driving T helper 1 cytokine and interleukin-17 production. Immunology, 2014-0141(3):388-400.
PMID: 24164540 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayWang Y et al. (2014-02-13), The transcription factors T-bet and Runx are required for the ontogeny of pathogenic interferon-gamma-producing T helper 17 cells. Immunity, 2014-040(3):355-66.
PMID: 24530058 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIkeda S et al. (2014-01-15), Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-beta-induced Foxp3 expression. J Immunol, 2014-0192(4):1449-58.
PMID: 24431229 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGuo X et al. (2014-01-09), Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection. Immunity, 2014-040(1):25-39.
PMID: 24412612 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYang C et al. (2014-01-08), Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation. J Immunol, 2014-0192(4):1547-57.
PMID: 24403530 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayPierson E et al. (2013-12-23), B cells promote induction of experimental autoimmune encephalomyelitis by facilitating reactivation of T cells in the central nervous system. J Immunol, 2013-1192(3):929-39.
PMID: 24367024 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAshino S et al. (2013-12-22), Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses. J Allergy Clin Immunol, 2013-1133(4):1162-74.
PMID: 24365136 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayLiu Y et al. (2013-12-09), Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. J Immunol, 2013-1192(1):59-72.
PMID: 24323580 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFisher Y et al. (2013-12-04), Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance. J Immunol, 2013-1192(1):92-102.
PMID: 24307730 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayChen J et al. (2013-10-28), Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis. J Immunol, 2013-1191(11):5441-50.
PMID: 24166976 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMascanfroni et al. (2013-09-01), IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol, 2013-014(10):1054-63.
PMID: 23995234 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIshida H et al. (2013-08-19), IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages. Eur J Immunol, 2013-043(10):2696-706.
PMID: 23843079 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureLiu H et al. (2013-06-03), ERK differentially regulates Th17- and Treg-cell development and contributes to the pathogenesis of colitis. Eur J Immunol, 2013-043(7):1716-26.
PMID: 23620016 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayYanaba K et al. (2013-04-29), Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. J Leukoc Biol, 2013-094(4):563-73.
PMID: 23630391 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMatsumoto A et al. (2013-04-23), IL-22-producing RORgammat-dependent innate lymphoid cells play a novel protective role in murine acute hepatitis. PLoS ONE, 2013-08(4):e62853.
PMID: 23626860 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassaySimons D et al. (2013-02-18), Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J Immunol, 2013-0190(7):3134-41.
PMID: 23420889 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFlanagan K et al. (2012-07-06), Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS. PLoS ONE, 2012-07(7):e40443.
PMID: 22792325 -
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay(2012-06-04), Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A, 2012-0109(25):9971-6.
PMID: 22665806 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCasey KA et al. (2012-04-13), Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol., 2012-0188(10):4866-75.
PMID: 22504644 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayAlcaide P et al. (2012-01-04), Difference in Th1 and Th17 lymphocyte adhesion to endothelium. J. Immunol., 2012-0188(3):1421-30.
PMID: 22219321 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMonticelli LA et al. (2011-11-01), Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat. Immunol., 2011-112(11):1045-54.
PMID: 21946417 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGessner MA et al. (2011-10-28), Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus. Infect. Immun., 2011-180(1):410-7.
PMID: 22038916 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoDubin PJ et al. (2011-10-24), Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect. Immun., 2011-180(1):398-409.
PMID: 22025517 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoFridman JS et al. (2011-06-16), Preclinical Evaluation of Local JAK1 and JAK2 Inhibition in Cutaneous Inflammation. J. Invest. Dermatol., 2011-0131(9):1838-44.
PMID: 21677670 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBreslow JM et al. (2011-05-16), Innate immune responses to systemic Acinetobacter baumannii infection in mice: neutrophils, but not interleukin-17, mediate host resistance. Infect. Immun., 2011-079(8):3317-27.
PMID: 21576323 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMa Y et al. (2011-03-07), Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J. Exp. Med., 2011-0208(3):491-503.
PMID: 21383056 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoNakajima K et al. (2011-02-23), Distinct Roles of IL-23 and IL-17 in the Development of Psoriasis-Like Lesions in a Mouse Model. J. Immunol., 2011-0186(7):4481-9.
PMID: 21346238 -
Species: Mouse
Sample Types: In Vivo,Whole Cells
Applications: In Vivo,BioassaySawa S et al. (2011-02-20), RORgammat+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat. Immunol., 2011-012(4):320-6.
PMID: 21336274 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDePaolo RW et al. (2011-02-09), Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature, 2011-0471(7337):220-4.
PMID: 21307853 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoKayamuro H et al. (2010-09-29), Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J. Virol., 2010-084(24):12703-12.
PMID: 20881038 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayJones GW et al. (2010-09-08), Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J., 2010-025(1):409-19.
PMID: 20826539 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayDe Luca A et al. (2010-05-05), IL-22 defines a novel immune pathway of antifungal resistance. Mucosal Immunol, 2010-03(4):361-73.
PMID: 20445503 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayCho JS et al. (2010-04-01), IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest., 2010-0120(5):1762-73.
PMID: 20364087 -
Species: Mouse
Sample Types: Whole Cells
Applications: Cell CultureMeeks KD et al. (2009-12-15), IL-23 is required for protection against systemic infection with Listeria monocytogenes. J. Immunol., 2009-1183(12):8026-34.
PMID: 19923464 -
Species: Mouse
Sample Types: In Vivo,N/A
Applications: ELISA (Standard),In VivoLemos HP et al. (2009-03-16), Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Proc. Natl. Acad. Sci. U.S.A., 2009-0106(14):5954-9.
PMID: 19289819 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHamada H et al. (2009-03-15), Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge. J. Immunol., 2009-0182(6):3469-81.
PMID: 19265125 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayMcKinley L et al. (2008-09-15), TH17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice. J. Immunol., 2008-0181(6):4089-97.
PMID: 18768865 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayShinohara ML et al. (2008-07-18), Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity, 2008-029(1):68-78.
PMID: 18619869 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayGuo B et al. (2008-05-01), The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest., 2008-0118(5):1680-90.
PMID: 18382764 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoSmith E et al. (2007-12-15), IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice. J. Immunol., 2007-1179(12):8274-9.
PMID: 18056371 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayFitzgerald DC et al. (2007-11-11), Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol., 2007-18(12):1372-9.
PMID: 17994023 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayZelante T et al. (2007-10-01), IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol., 2007-137(10):2695-706.
PMID: 17899546 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBrustle A et al. (2007-08-05), The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immunol., 2007-08(9):958-66.
PMID: 17676043 -
Species: Mouse
Sample Types: In Vivo
Applications: In VivoNakano N et al. (2007-02-08), Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections. Blood, 2007-0109(11):4846-55.
PMID: 17289816 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayIvanov S et al. (2006-12-01), Functional relevance of the IL-23-IL-17 axis in lungs in vivo. Am. J. Respir. Cell Mol. Biol., 2006-136(4):442-51.
PMID: 17142310 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayBettelli E et al. (2006-04-30), Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature, 2006-0441(7090):235-8.
PMID: 16648838 -
Species: Mouse
Sample Types: Whole Cells
Applications: BioassayHarrington et al. (2005-10-02), Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol, 2005-16(11):1123-32.
PMID: 16200070
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Customer Reviews for Recombinant Mouse IL-23 Protein (5)
Customer Images
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Application: Cell ProliferationVerified Customer | Posted 05/23/2020
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Application: Stem/Immune cell maintenance or differentiationVerified Customer | Posted 03/17/2020
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Application: Glycosylation characterization by MSVerified Customer | Posted 02/07/2018
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Application: CD4+ T Cell polarization toward Th17Verified Customer | Posted 08/24/2017
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Application: Cell ProliferationVerified Customer | Posted 08/24/2016
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FAQs for Recombinant Mouse IL-23 Protein
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Q: Should I use Recombinant Mouse IL-23 Protein formulated with carrier BSA (Catalog # 1887-ML) or the Recombinant Mouse IL-23 Protein, CF (Catalog # 1887-ML/CF) that is carrier-free (no BSA) for my in vivo experiments?
A: For in vivo aplications, we would recommend using the carrier-free Mouse IL-23 Protein (Catalog # 1887-ML/CF). The injection of a carrier protein such as BSA can cause side effects and sometimes death to the experimental animal. For more information regarding use of the protein for in vivo applications, we would recommend consulting the Citations tab on the product-specific page.
Reconstitution Calculator
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