Recombinant Human Integrin alpha V beta 6 Protein, CF Best Seller
Catalog # 3817-AV | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Source
Structure / Form
Conjugate
Applications
Product Specifications
Source
Human Integrin alphaV (Phe31-Val992) Accession # NP_002201.1 |
His-Pro | GGGSGGGS | Acidic Tail |
Human Integrin beta6 (Gly22-Asn707) Accession # P18564 |
His-His-Pro | GGGSGGGS | Basic Tail |
N-terminus | C-terminus |
Purity
Endotoxin Level
N-terminal Sequence Analysis
Predicted Molecular Mass
SDS-PAGE
Activity
Immobilized Recombinant Human Integrin alphaV beta6 at 2.0 µg/mL can bind Recombinant Human LAP TGF‑ beta1 (Catalog # 246-LP) with an apparent Kd
Formulation, Preparation and Storage
3817-AV
Formulation | Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and CaCl2. |
Reconstitution |
Reconstitute at 100 μg/mL in sterile PBS.
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Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Background: Integrin alpha V beta 6
References
- Hynes, R.O. (2002) Cell 110:673.
- Sheppard, D. (2004) Curr. Opin. Cell Biol. 16:552.
- Bandyopadhyay, A. and S. Raghavan (2009) Curr. Drug Targets 10:645.
- Suzuki, S. et al. (1987) J. Biol. Chem. 262:14080.
- Sheppard, D. et al. (1990) J. Biol. Chem. 265:11502.
- Dixit, R.B. et al. (1996) J. Biol. Chem. 271:25976.
- Munger, J.S. et al. (1999) Cell 96:319.
- Fontana, L. et al. (2005) FASEB J. 19:1798.
- Jenkins, R.G. et al. (2006) J. Clin. Invest. 116:1606.
- Huang, X.Z. et al. (1996) J. Cell Biol. 133:921.
- Morris, D.G. et al. (2003) Nature 422:169.
- Chen, X. et al. (2011) J. Leukoc. Biol. 90:751.
- Berryman, S. et al. (2005) J. Virol. 79:8519.
- Heikkila, O. et al. (2009) J. Gen. Virol. 90:197.
Alternate Names
Entrez Gene IDs
Gene Symbol
Product Documents for Recombinant Human Integrin alpha V beta 6 Protein, CF
Product Specific Notices for Recombinant Human Integrin alpha V beta 6 Protein, CF
For research use only
Citations for Recombinant Human Integrin alpha V beta 6 Protein, CF (8)
Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human Integrin alpha V beta 6 Protein, CF include:
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Species: N/A
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance (SPREG Norris et al. (2022-04-11), Receptor binding domain of SARS-CoV-2 is a functional alphav-integrin agonist bioRxiv : the preprint server for biology, 2022-00(0).
PMID: 35441172 -
Species: Human
Sample Types: Serum
Applications: ELISA CaptureN Rydell et al. (2022-03-28), Measurement of Serum IgG Anti-Integrin alphavbeta6 Autoantibodies Is a Promising Tool in the Diagnosis of Ulcerative Colitis Journal of Clinical Medicine, 2022-011(7).
PMID: 35407486 -
Species: Human
Sample Types: Cell Culture Supernates
Applications: BioassayM Uzzan et al. (2022-02-21), Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity Nature Medicine, 2022-00(0).
PMID: 35190725 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayM Bieri et al. (2021-12-15), The RGD-binding integrins alphavbeta6 and alphavbeta8 are receptors for mouse adenovirus-1 and -3 infection PloS Pathogens, 2021-117(12):e1010083.
PMID: 34910784 -
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA Developmet(2016-12-06), Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains Sci Rep, 2016-16(0):38101.
PMID: 27922023 -
Species: Virus
Sample Types: Protein
Applications: Bioassay(2016-08-05), Truncated Bovine Integrin Alpha-v/Beta-6 as a Universal Capture Ligand for FMD Diagnosis PLoS ONE, 2016-011(8):e0160696.
PMID: 27494135 -
Species: Human
Sample Types: Whole Cells
Applications: BioassayBarbariga et al. (2013-12-23), Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling. J Biol Chem, 2013-1289(6):3736-48.
PMID: 24366863 -
Species: Human
Sample Types: Peptide
Applications: Binding AssayCurnis F et al. (2010-01-11), Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching. J. Biol. Chem., 2010-0285(12):9114-23.
PMID: 20064928
There are no citations that match your criteria.
Customer Reviews for Recombinant Human Integrin alpha V beta 6 Protein, CF (2)
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Application: Cell migration/motilityVerified Customer | Posted 12/04/2020
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Application: Binding assay/Protein-protein interactionVerified Customer | Posted 10/26/2020
There are no reviews that match your criteria.
FAQs for Recombinant Human Integrin alpha V beta 6 Protein, CF
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Q: What is the amino acid sequence of the acidic and basic tails?
A: Acidic and basic tails are added to the protein to help facilitate optimal activity. While we generally include sequence information on the product datasheet, the sequences of these tails are considered confidential information.
Reconstitution Calculator
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