(R)-(-)-Niguldipine hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 1124

α1 antagonist, L-type Ca2+ channel blocker. Less active enantiomer of Niguldipine hydrochloride (Cat. No. 1123)
Discontinued Product
1124 has been discontinued. View all Adrenergic alpha-1 Receptor Antagonists products.

Key Product Details

Description

α1 antagonist, L-type Ca2+ channel blocker. Less active enantiomer of Niguldipine hydrochloride (Cat. No. 1123)

View all Adrenergic alpha-1 Receptor Antagonists »

Product Description

(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist; less active enantiomer.

S-enantiomer also available.

Product Specifications

Molecular Weight

646.18

Formula

C36H39N3O6.HCl

Storage

Desiccate at -20°C

Chemical Name

(R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride

CAS Number

113145-70-3

PubChem ID

16219720

InChI Key

MHOSUIMBPQVOEU-WAQYZQTGSA-N

SMILES

O=C(OC)C1=C(C)NC(C)=C(C(OCCCN3CCC(C4=CC=CC=C4)(C5=CC=CC=C5)CC3)=O)[C@@H]1[C@]2=CC=CC([N+]([O-])=O)=C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10

Preparing Stock Solutions for (R)-(-)-Niguldipine hydrochloride

The following data is based on the product molecular weight 646.18

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.48 mL 77.38 mL 154.76 mL
0.5 mM 3.10 mL 15.48 mL 30.95 mL
1 mM 1.55 mL 7.74 mL 15.48 mL
5 mM 0.31 mL 1.55 mL 3.10 mL

Calculators

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Reconstitution Calculator

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Product Documents for (R)-(-)-Niguldipine hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (R)-(-)-Niguldipine hydrochloride

For research use only

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