(R)-(+)-Blebbistatin
Tocris Bioscience, part of Bio-Techne | Catalog # 1853
Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)
Discontinued Product
1853 has been discontinued.
View all Myosin Inhibitors products.
Key Product Details
Description
Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760)
Product Description
(R)-(+)-Blebbistatin is an inactive enantiomer of the selective inhibitor of myosin II (±)-blebbistatin.Active Enantiomer and Racemate also available.
Product Specifications
Molecular Weight
292.34
Formula
C18H16N2O2
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
(3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one
CAS Number
1177356-70-5
PubChem ID
6604910
InChI Key
LZAXPYOBKSJSEX-SFHVURJKSA-N
SMILES
O=C2[C@]3(O)C(N(C4=CC=CC=C4)CC3)=NC1=CC=C(C)C=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.23 | 100 |
Preparing Stock Solutions
for (R)-(+)-Blebbistatin
The following data is based on the product molecular weight 292.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.42 mL | 17.10 mL | 34.21 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
| 10 mM | 0.34 mL | 1.71 mL | 3.42 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Straight Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 2003 PMID: 12637748
- Straight Dissecting cytokinesis with small molecules. Amer.Soc.Cell Biol.Abstr.
- Limouze Specificity of blebbistatin, an inhibitor of myosin II. J.Muscle Res.Cell Motil. 2004 PMID: 15548862
Product Specific Notices for (R)-(+)-Blebbistatin
For research use only
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