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Maurice C.

Catalog # 090-002 | ProteinSimple a Bio-Techne Brand
Maurice C. - Identity and charge heterogeneity
My molecule has complicated charge profiles that are difficult to resolve
My current method is not reproducible and error-prone
I have many samples and my schedule is tight
My sample is limited and they tend to aggregate at high concentration

Identity and charge heterogeneity

Maurice C. runs cIEF applications on your mAbs, ADCs, and vaccines faster than anything out there. We're talking 10 minutes per sample and method development in a day. You get reliable and reproducible data day in and day out with single-digit CVs, and resolution that trumps HPLC. Get compliant data with either Compass for iCE or Waters Empower software.

Identity and charge heterogeneity

Streamline your CE workflow with Maurice C who delivers identity, purity and heterogeneity data on your biologics fast. This cIEF application video show how you can get reliable data in 10 minutes.

Citations for Maurice C.

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Testimonials from your Peers for Imaged Capillary Electrophoresis (iCE)

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"The short run times and easy sample preparation allowed for method development within a day or two. The versatility of the instrument allows the possibility of offering clients rapid alternatives to traditional ID and charge heterogeneity assays."

Joan Garrison, QC Method Transfer Scientist, Cook Pharmica

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More Information About Maurice C.

Feature cIEF Specification
Minimum Sample Volume 50 µL
Sample Delivery Vacuum
Typical Separation Time 6-10 min (molecule-dependent)
Detection Capability UV Absorbance at 280nm
Fluorescence: Ex 280nm, Em 320-450nm
Typical Voltage Pre-focusing: 1500 V, focusing: 3000 V
Sample Injections per Cartridge 100
Maximum Sample Injections per Batch 100 guaranteed, 200 maximum
pl Range 2.85-10.45
pl CV 1%
CV for Peaks >10% Composition ≤5% (Intra-batch), ≤6% (Inter-batch)
pl Resolution 0.05 pl units (for wide range 3-10 ampholytes)
Dynamic Range 2 logs
Linearity >0.995
Sensitivity (LOD) 0.7 µg/mL (Native fluorescence)
3.0 µg/mL (Absorbance)
(Values based on a monoclonal antibody)
Sample Tray Options 96-well plates or 48 vials
Dimensions 44cm H x 42 cm W x 61 cm D
Weight 46 kg (100 lb)