FITC-CHIPOpt
Tocris Bioscience, part of Bio-Techne | Catalog # 8045
Fluorescent CHIP/STUB1 E3 ligase inhibitor
Discontinued Product
8045 has been discontinued.
View all Fluorescent Probes products.
Key Product Details
Description
Fluorescent CHIP/STUB1 E3 ligase inhibitor
Product Description
FITC-CHIPOpt is a fluorescent CHIP/STUB1 E3 ligase inhibitor. It binds to CHIP and can be used in CHIP fluorescent polarization (FP) binding assays. Enables CHIP FP binding assays to be developed for new inhibitor or CHIP ligand synthesis. FITC-CHIPOpt is the fluorescent version of CHIPOp (Cat. No. 8044).Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Product Specifications
Molecular Weight
1218.35
Formula
C64H67N9O14S
Storage
Store at -20°C
Purity
≥95% (HPLC)
InChI Key
WHLHAYSAZOFWTL-TVKYAJOTSA-N
SMILES
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N5[C@@H](CCC5)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)[C@H](CC(C)C)NC(CCCCCNC(NC(C=C6C(O)=O)=CC=C6C(C7=C8C=C(O)C=C7)=C(C=C9)C(O8)=CC9=O)=S)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in PBS |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Ravalin Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases. Nat.Chem.Biol. 2019 PMID: 31320752
- Nadel The E3 ubiquitin ligase, CHIP/STUB1, inhibits aggregation of phosphorylated proteoforms of microtubule-associated protein tau (MAPT). J.Mol.Biol. 2023 PMID: 37330289
Product Specific Notices for FITC-CHIPOpt
For research use only
Loading...
Loading...