Can samples be tested without activation in Human TGF-beta 1 Quantikine® ELISA Kit, Catalog # DB100B, to determine levels of endogenously mature TGF-beta 1?

Name: Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA
Brand: R&D Systems
SKU: DB100B
Rating: 5 (20 reviews)

Catalog # DB100B is designed to measure TGF-beta 1 in activated serum and plasma samples. Activation releases TGF-beta 1 from latent TGF-beta 1 complexes. Internal tests with latent TGF-beta complex have demonstrated approximately 15% reactivity in the kit; however it is unclear whether this may be partially due to activation of latent TGF-beta 1 once added to the assay plate. Since the latent form of TGF-beta 1 may be significantly more abundant in serum and plasma, this cross-reactivity may make it difficult to measure low levels of active TGF-beta 1. Therefore, we recommend only using the kit to test activated serum and plasma samples for total TGF-beta 1 levels.

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

R&D Systems, Inc. a Bio-Techne Brand

Catalog # DB100B

Citations (391)

(20)

Product Datasheet / COA / SDS

New Version Available - DB100C

This product has been discontinued

Discontinued Product

DB100B has been discontinued and is replaced by DB100C.

Setting the standard in quality research reagents

Key Product Details

Assay Length:	4.5 hours
Sample Type & Volume Required Per Well:	Cell Culture Supernates (100 uL), Serum (40 uL), EDTA Plasma (40 uL), Platelet-poor Plasma (25 uL), Urine (100 uL)
Sample Types:	Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Plasma, Urine
Sensitivity:	15.4 pg/mL
Assay Range:	31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor Plasma, Urine)
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA Summary:	The Quantikine Human TGF-beta 1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure TGF-beta 1 in acid activated cell culture supernates, serum, plasma, and urine. It contains recombinant human TGF-beta 1 expressed by CHO cells and has been shown to quantitate the recombinant factor accurately. Results obtained using natural TGF-beta 1 showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit will provide accurate quantitation for both recombinant and natural human TGF-beta 1.

View Full Technical Details for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Product Specifications for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Measurement	Quantitative ELISA
Detection Method	Colorimetric - 450nm (TMB)
Conjugate	HRP
Reactivity	Human
Specificity	Natural and recombinant TGF-beta 1. This kit cross-reacts 15% with human Latent TGF-beta 1 complex and also recognizes human TGF-beta 1.2 and mouse, rat, porcine, and canine TGF-beta 1.
Cross-reactivity	Cross-reactivity observed with 1 or more available related molecules. Cross-species reactivity observed with 1 or more species tested.
Interference	Interference observed with 1 or more available related molecules.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision

Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Urine

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	22	21	22
Mean (pg/mL)	88	198	816	97	209	826
Standard Deviation	3	4.9	19.6	8.1	17.3	47
CV%	3.4	2.5	2.4	8.4	8.3	5.7

Serum, EDTA Plasma

	Intra-Assay Precision			Inter-Assay Precision
Sample	1	2	3	1	2	3
n	20	20	20	28	37	30
Mean (pg/mL)	78	180	695	79	185	730
Standard Deviation	2.3	3.4	17.3	7.2	17.2	46.8
CV%	2.9	1.9	2.5	9.1	9.3	6.4

Recovery

The recovery of TGF-beta 1 spiked to levels throughout the range of the assay followed by activation was evaluated.

Sample Type	Average % Recovery	Range %
Cell Culture Supernates (n=4)	99	86-115
Urine (n=3)	96	88-100

Linearity

To assess the linearity of the assay, activated samples containing and/or spiked with high concentrations of TGF-beta 1 were diluted with Calibrator Diluent and then assayed.

Scientific Data Examples for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

	Human TGF-beta 1 ELISA Cell Culture Supernate/Urine Standard Curve
	Human TGF-beta 1 ELISA Serum/Plasma Standard Curve

Preparation and Storage

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: TGF-beta 1

Human TGF-beta 1 is a 25 kDa, disulfide-linked homodimeric protein involved in a number of key developmental, immunologic, and homeostatic processes (1-4). The molecule is synthesized as a 390 amino acid (aa) precursor that contains a 23 aa signal sequence, a 255 aa pro-region, and a 112 aa mature segment. Processing of the molecule is complex, and it is generally secreted as a latent form (5). Prior to release, the prepro-form is cleaved of its signal sequence, followed by glycosylation of its pro-region. The glycosylation process includes the unusual attachment of mannose-6 phosphate residues. This is followed by furin convertase-mediated cleavage of the prohormone, creating an 80 kDa disulfide-linked proregion (termed LAP for latency-associated protein), plus a 25 kDa disulfidelinked mature segment (termed TGF-beta 1) (6-8). These two independent disulfide-linked polypeptides associate in a non-covalent interaction that renders TGF-beta 1 inactive. Although direct secretion of this 80K:25K complex can occur, it does so inefficiently. To facilitate secretion plus extracellular storage, a third 200 kDa component termed LTBP is covalently-linked to the N-terminus of one of the two LAP polypeptide chains. This promotes secretion and subsequent storage within the extracellular matrix (9, 10). After secretion, TGF-beta 1, via LTBP, covalently links to ECM. This complex is later cleaved by proteases and released, exposing mannose residues on LAP. It is postulated that exposed LAP mannose residues now are able to bind to cell surface IGF-II R, where dissociative events disrupt the LAP-TGF-beta 1 complex. This results in the release of active, homodimeric TGF-beta 1 (7, 10). Mature mouse TGF-beta 1 shares 100% aa sequence identity with rat and cotton rat TGF-beta 1 (11, 12), 99% aa identity with human, canine, and porcine TGF-beta 1 (13, 14, 15), and 97% aa identity with guinea pig TGF-beta 1 (16). Relative to mouse TGF-beta 2 and beta 3, mature mouse TGF-beta 1 shares 72% and 78% aa sequence identity, respectively (17, 18).

The traditional high-affinity receptor for TGF-beta 1 is a heteromeric complex consisting of transmembrane serine/threonine kinases. Two types are involved; a constitutively phosphorylated, ligand-binding 80 kDa glycoprotein termed T beta RII and a signal-transducing, non-ligand-binding 55 kDa glycoprotein termed T beta RI/ALK-5 (19-22). It is suggested that TGF-beta 1first binds T beta RII, which then initiates a crossphosphorylation of T beta RI, culminating in signal transduction. There is also a third TGF-beta receptor termed T beta RIII, which can be either the 250 kDa proteoglycan named betaglycan, or the 180 kDa glycoprotein termed endoglin/CD105 (23, 24). It has been proposed that T beta RIII captures TGF-beta and "passes" it to T beta RII (20). This is perhaps true for betaglycan but not endoglin. Endoglin does not bind TGF-beta by itself; only within the context of T beta RII ligand binding. Evidence suggests that rather than "passing" on ligand, endoglin may actually enter the receptor complex and modulate TGF-beta downstream signaling (25, 26). Finally, and although ALK-5 has traditionally been assumed to be the only type I signaling receptor for TGF-beta 1, it is also possible that ALK-1 may serve as a condition-dependent, type I TGF-beta receptor (27).

TGF-beta 1 has a wide range of activities. During an immune response, TGF-beta 1 impacts antibody production by preferentially induceing IgA production in both mouse and human (28). It also regulates dendritic cell chemotaxis by altering the expression of chemokine receptors (29). Finally, it can downmodulate an inflammatory response by dampening macrophage activity and proinflammatory secretion (30). During wound healing, TGF-beta 1 is released from activated platelets. This local source of TGF-beta 1 has marked stimulatory effects on fibroblasts, where it induces matrix synthesis; on monocytes, where it induces proinflammatory mediator and growth factor secretion; and on keratinocytes, where it may promote keratinocyte proliferation by downmodulating its own signaling pathway (31). Finally, during development, TGF-beta 1 may play a role in endochondral ossification, and its absence results in severely defective yolk sac vasculogenesis and hematopoiesis (32, 33).

Item	Value
Long Name	Transforming Growth Factor beta 1
Entrez Gene IDs	7040 (Human); 21803 (Mouse); 59086 (Rat); 397078 (Porcine); 100033900 (Equine)
Alternate Names	CEDLAP, DPD1, TGF beta, TGF beta1, TGF-beta 1, TGF-beta 1 protein, TGF-beta-1, TGFB, TGFB1, TGFbeta, TGFbeta 1, latency-associated peptide, transforming growth factor beta-1, transforming growth factor, beta 1

Citations for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA (391)

Showing 1 - 10 of 391 citations Showing All

Filter By:

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA include:

Species: Human
Sample Types: Cell Culture Supernates

EA Ross et al. (2023), Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells Nature Communications, 14(1):753.
PMID: 36765065
Species: Human
Sample Types: Cell Culture Supernates

É Velot et al. (2022), Efficient TGF-beta1 Delivery to Articular Chondrocytes In Vitro Using Agro-Based Liposomes International Journal of Molecular Sciences, 23(5).
PMID: 35270005
Species: Human
Sample Types: Cell Culture Supernates

M Smeda et al. (2022), Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells International Journal of Molecular Sciences, 23(5).
PMID: 35269758
Species: Human
Sample Types: Cell Culture Supernates

C Bucchi et al. (2022), Human Amnion Epithelial Cells: A Potential Cell Source for Pulp Regeneration? International Journal of Molecular Sciences, 23(5).
PMID: 35269973
Species: Human
Sample Types: Serum

V Narayan et al. (2022), PSMA-targeting TGFbeta-insensitive armored CAR T?cells in metastatic castration-resistant prostate cancer: a phase 1 trial Nature Medicine, 0(0).
PMID: 35314843
Species: Human
Sample Types: Plasma

YC Liu et al. (2022), TGF-beta1 in plasma and cerebrospinal fluid can be used as a biological indicator of chronic pain in patients with osteoarthritis PLoS ONE, 17(1):e0262074.
PMID: 35061744
Species: Mouse
Sample Types: Serum

M Zingariell et al. (2022), Resident Self-Tissue of Proinflammatory Cytokines Rather Than Their Systemic Levels Correlates with Development of Myelofibrosis in Gata1low Mice Biomolecules, 12(2).
PMID: 35204735
Species: Human
Sample Types: Breast Milk

J Štšepetova et al. (2022), Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring Scientific Reports, 12(1):6607.
PMID: 35459889
Species: Rat
Sample Types: Serum

K Chen et al. (2022), Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation Cell Transplantation, 31(0):9636897221089.
PMID: 35438583
Species: Human
Sample Types: BALF

J Zhang et al. (2022), Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity Nature Immunology, 0(0).
PMID: 35075279
Species: Human
Sample Types: Serum

X García-Del et al. (2022), Molecular Biomarkers of Prognosis in Advanced Renal Cell Carcinoma Patients Treated With Pazopanib Plus Interferon Alpha (INF-2A) in a Phase I/II Study by the Spanish Oncology Genitourinary Group Clinical genitourinary cancer, 0(0).
PMID: 35428584
Species: Equine
Sample Types: Cell Culture Supernates

K Fukuda et al. (2022), Platelet lysate enhances equine skeletal muscle regeneration in a bupivacaine-induced muscle injury model Journal of equine veterinary science, 0(0):103892.
PMID: 35124154
Species: Human
Sample Types: Plasma

B Wang et al. (2022), Acrylamide exposure increases cardiovascular risk of general adult population probably by inducing oxidative stress, inflammation, and TGF-beta1: A prospective cohort study Environment international, 164(0):107261.
PMID: 35486963
Species: Human
Sample Types: Cell Culture Supernates

K Sobierajsk et al. (2022), Oxidative Stress Enhances the TGF-beta2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition International Journal of Molecular Sciences, 23(4).
PMID: 35216178
Species: Human
Sample Types: Serum

A Gidaro et al. (2022), Incidence of Venous Thromboembolism in Multiple Myeloma Patients across Different Regimens: Role of Procoagulant Microparticles and Cytokine Release Journal of Clinical Medicine, 11(10).
PMID: 35628848
Species: Rat
Sample Types: Serum

W Feng et al. (2022), Study on the effect and mechanism of quercetin in treating gout arthritis International immunopharmacology, 111(0):109112.
PMID: 35932610
Species: Human
Sample Types: Breast Milk

N Hirata et al. (2022), Association between Maternal Characteristics and Immune Factors TGF-beta1, TGF-beta2, and IgA in Colostrum: An Exploratory Study in Japan Nutrients, 14(16).
PMID: 36014760
Species: Mouse
Sample Types: Cell Culture Supernates

Y Wang et al. (2022), GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathy Cell Death Disease, 2022;13(8):693.
PMID: 35941120
Species: Human
Sample Types: Cell Culture Supernates

W Singhatana et al. (2022), IFNgamma-primed periodontal ligament cells regulate T-cell responses via IFNgamma-inducible mediators and ICAM-1-mediated direct cell contact Royal Society open science, 9(7):220056.
PMID: 35911203
Species: Mouse
Sample Types: Cell Culture Supernates

S Pradhan et al. (2022), Activation of TLR-pathway to induce host Th1 immune response against visceral leishmaniasis: Involvement of galactosylated-flavonoids Heliyon, 8(7):e09868.
PMID: 35847617
Species: Human
Sample Types: Cell Culture Supernates

Z Wu et al. (2022), LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination Journal of Immunology Research, 2022(0):6450721.
PMID: 36118415
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates

J Trink et al. (2022), Integrin beta1/Cell Surface GRP78 Complex Regulates TGFbeta1 and Its Profibrotic Effects in Response to High Glucose Biomedicines, 10(9).
PMID: 36140347
Species: Mouse
Sample Types: Cell Culture Supernates

S Ortega-Peñ et al. (2022), Dialkyl Carbamoyl Chloride-Coated Dressing Prevents Macrophage and Fibroblast Stimulation via Control of Bacterial Growth: An In Vitro Assay Microorganisms, 10(9).
PMID: 36144427
Species: Human
Sample Types: BALF

AC Fears et al. (2022), Exposure modality influences viral kinetics but not respiratory outcome of COVID-19 in multiple nonhuman primate species PloS Pathogens, 18(7):e1010618.
PMID: 35789343
Species: Human
Sample Types: Cell Culture Supernates

KI Matsumoto et al. (2022), COL1A1 expression induced by overexpression of both a 15?amino acid peptide from the fibrinogen domain of tenascin?X and integrin alpha11 in LX?2 cells Molecular Medicine Reports, 26(5).
PMID: 36069233
Species: Human
Sample Types: Cell Culture Supernates

S Biswas Shi et al. (2022), Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder Oncogene, 0(0).
PMID: 35739007
Species: Human
Sample Types: Serum

Y Zhao et al. (2022), A prospective study comparing the inflammation-related cytokine and chemokine profile from the day of blastocyst transfer to 7 weeks of gestation between pregnancies that did or did not result in a miscarriage Journal of reproductive immunology, 154(0):103755.
PMID: 36272272
Species: Mouse
Sample Types: Cell Culture Supernates

K Tange et al. (2022), Oral administration of human carbonic anhydrase I suppresses colitis in a murine inflammatory bowel disease model Scientific Reports, 12(1):17983.
PMID: 36289244
Species: Canine
Sample Types: Cell Culture Supernates

AM Soileau et al. (2022), The Effect of Arginase on Canine T-Lymphocyte Functions and its Modulation by All-Trans Retinoid Acid (ATRA) in Canine Monocyte-Derived Macrophages Oncogene, 9(7).
PMID: 35878391
Species: Canine
Sample Types: Serum

L Krakowski et al. (2022), Assessment of the possibility of using biomarkers (CCL11 and TGF-beta 1) in the diagnosis of prostate gland hyperplasia in dogs Theriogenology, 192(0):9-13.
PMID: 36030614
Species: Primate - Chlorocebus aethiops (African Green Monkey)
Sample Types: Tissue Lysates

AD Ruggiero et al. (2022), Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity International Journal of Molecular Sciences, 23(20).
PMID: 36293536
Species: Human
Sample Types: Serum

RM Critelli et al. (2022), Upregulation of the oestrogen target gene SIX1 is associated with higher growth speed and decreased survival in HCV-positive women with hepatocellular carcinoma Oncology Letters, 24(5):395.
PMID: 36276500
Species: Human
Sample Types: Serum

K Kop?ali? et al. (2022), Circulating levels of IL-6 and TGF-beta1 in patients with prostate cancer undergoing radiotherapy: associations with acute radiotoxicity and fatigue symptoms BMC Cancer, 22(1):1167.
PMID: 36368974
Species: Human
Sample Types: Serum

I Soveral et al. (2022), Cord Blood Cardiovascular Biomarkers in Left-Sided Congenital Heart Disease Journal of Clinical Medicine, 11(23).
PMID: 36498692
Species: Human
Sample Types: Cell Culture Supernates

Z Shen et al. (2022), Roseburia intestinalis stimulates TLR5-dependent intestinal immunity against Crohn's disease EBioMedicine, 85(0):104285.
PMID: 36182776
Species: Rat
Sample Types: BALF

AH Kadam et al. (2022), Targeting caveolae to pump bispecific antibody to TGF-beta into diseased lungs enables ultra-low dose therapeutic efficacy PLoS ONE, 17(11):e0276462.
PMID: 36413536
Species: Mouse
Sample Types: Tissue Homogenates

S Piñeiro-He et al. (2022), Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development Nature Communications, 13(1):5656.
PMID: 36202783
Species: Human
Sample Types: Whole Blood

C Cui et al. (2022), Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor BMC immunology, 23(1):58.
PMID: 36434505
Species: Human
Sample Types: Serum

M Macías et al. (2021), Characterization of the perioperative changes of exosomal immune-related cytokines induced by prostatectomy in early-stage prostate cancer patients Cytokine, 141(0):155471.
PMID: 33607398
Species: Human
Sample Types: Serum

S Sriphoosan et al. (2021), Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial PeerJ, 9(0):e10709.
PMID: 33614272
Species: Human
Sample Types: Plasma

JJ Harding et al. (2021), Phase 1b study of galunisertib and ramucirumab in patients with advanced hepatocellular carcinoma Cancer Medicine, 0(0).
PMID: 33811482
Species: Human
Sample Types: Serum

A Tavakoli et al. (2021), Circulating inflammatory markers may mediate the relationship between low carbohydrate diet and circadian rhythm in overweight and obese women Oncogene, 21(1):87.
PMID: 33648476
Species: Human
Sample Types: Serum

C Guo et al. (2021), Serum sphingolipid profile in asthma Journal of leukocyte biology, 0(0).
PMID: 33600023
Species: Human
Sample Types: Plasma

BK Jeong et al. (2021), Cytokine Profiles of Non-Small Cell Lung Cancer Patients Treated with Concurrent Chemoradiotherapy with Regards to Radiation Pneumonitis Severity Journal of Clinical Medicine, 10(4).
PMID: 33670117
Species: Human
Sample Types: Cell Culture Supernates

Z Ma et al. (2021), Role of CXCL16 in BLM-induced epithelial-mesenchymal transition in human A549 cells Respiratory Research, 22(1):42.
PMID: 33549109
Species: Human
Sample Types: Plasma

MM Brunton-O' et al. (2021), A combined biomarker approach for characterising extracellular matrix profiles in acute myocardial infarction Scientific Reports, 11(1):12705.
PMID: 34135421
Species: Human
Sample Types: Cell Culture Supernates

KV Manian et al. (2021), 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration Cell Stem Cell, 0(0).
PMID: 33784497
Species: Human
Sample Types: Cell Culture Supernates

S Wasai et al. (2021), Development of Injectable Polydactyly-Derived Chondrocyte Sheets International Journal of Molecular Sciences, 22(6).
PMID: 33801144
Species: Human
Sample Types: Plasma

N Casagrande et al. (2021), In Ovarian Cancer Multicellular Spheroids, Platelet Releasate Promotes Growth, Expansion of ALDH+ and CD133+ Cancer Stem Cells, and Protection against the Cytotoxic Effects of Cisplatin, Carboplatin and Paclitaxel International Journal of Molecular Sciences, 22(6).
PMID: 33809553
Species: Human
Sample Types: Cell Culture Supernates

C Zhang et al. (2021), Porphyromonas gingivalis lipopolysaccharide promotes T-hel per17 cell differentiation by upregulating Delta-like ligand 4 expression on CD14+ monocytes PeerJ, 9(0):e11094.
PMID: 33981487
Species: Human
Sample Types: Plasma

S Isozaki et al. (2021), Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators Mediators of Inflammation, 2021(0):5582943.
PMID: 33859537
Species: Human
Sample Types: Cell Culture Supernates

M Kimsa-Dude et al. (2021), A static magnetic field changes the expression profile of the transforming growth factor &beta family genes in human cells that have been treated with fluoride ions Cytokine, 0(0):155537.
PMID: 33867212
Species: Rat
Sample Types: Tissue Homogenates

A Soltani He et al. (2021), Protective effect of alamandine on doxorubicin?induced nephrotoxicity in rats Bmc Pharmacology Toxicology, 2021;22(1):31.
PMID: 34049594
Species: Mouse
Sample Types: BALF

Y Waseda et al. (2021), The pronounced lung lesions developing in LATY136F knock-in mice mimic human IgG4-related lung disease PLoS ONE, 16(3):e0247173.
PMID: 33661938
Species: Human
Sample Types: Plasma

I Thomas et al. (2021), The Role of Leptin in Childhood Immune Thrombocytopenia (ITP): An Anti-Inflammatory Agent? International Journal of Molecular Sciences, 22(14).
PMID: 34299256
Species: Human
Sample Types: Cell Culture Supernates

F Scavello et al. (2021), Soluble Receptor for Advanced Glycation End-products regulates age-associated Cardiac Fibrosis International journal of biological sciences, 17(10):2399-2416.
PMID: 34326683
Species: Human
Sample Types: Plasma

RL Relf et al. (2021), Thermoregulation is not impaired in breast cancer survivors during moderate-intensity exercise performed in warm and hot environments Physiological Reports, 9(14):e14968.
PMID: 34291605
Species: Mouse
Sample Types: Plasma

JZ Longenecke et al. (2021), Cardiac-derived TGF-beta1 confers resistance to diet-induced obesity through regulation of adipocyte size and function Molecular Metabolism, 0(0):101343.
PMID: 34583010
Species: Human
Sample Types: Cell Culture Supernates

H Liu et al. (2021), Endoplasmic reticulum stress inhibits 3D Matrigel-induced vasculogenic mimicry of breast cancer cells via TGF-beta1/Smad2/3 and beta-catenin signaling FEBS Open Bio, 0(0).
PMID: 34320274
Species: Human
Sample Types: Cell Culture Supernates

M Liu et al. (2021), Colon cancer cells secreted CXCL11 via RBP-Jkappa to facilitated tumour-associated macrophage-induced cancer metastasis Journal of Cellular and Molecular Medicine, 0(0).
PMID: 34655278
Species: Human
Sample Types: Serum

JS Nahand et al. (2021), Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer BMC Cancer, 21(1):926.
PMID: 34399719
Species: Human
Sample Types: Cell Culture Supernates

A Kuzumi et al. (2021), Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis Nature Communications, 12(1):5947.
PMID: 34642338
Species: Human
Sample Types: Cell Lysates

L Panahipour et al. (2021), TGF-&beta Activity of a Demineralized Bone Matrix International Journal of Molecular Sciences, 22(2).
PMID: 33440877
Species: Mouse
Sample Types: Cell Culture Supernates

R Morikawa et al. (2021), Intraepithelial lymphocytes suppress the intestinal tumor growth by cell-to-cell contact via CD103/E-cadherin signal Cellular and Molecular Gastroenterology and Hepatology, 0(0).
PMID: 33515805
Species: Human
Sample Types: Cell Culture Supernates

K Ueno et al. (2021), Freezing of cell sheets using a 3D freezer produces high cell viability after thawing Biochemistry and Biophysics Reports, 28(0):101169.
PMID: 34786495
Species: Human
Sample Types: Cell Culture Supernates

CM Borza et al. (2021), DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3 JCI Insight, 0(0).
PMID: 34941574
Species: Human
Sample Types: Cell Culture Supernates

M Gallego-Re et al. (2021), TGFbeta1 Secreted by Cancer-Associated Fibroblasts as an Inductor of Resistance to Photodynamic Therapy in Squamous Cell Carcinoma Cells Cancers, 13(22).
PMID: 34830768
Species: Human
Sample Types: Whole Cells

B Walters et al. (2021), Controlled Growth Factor Delivery and Cyclic Stretch Induces a Smooth Muscle Cell-like Phenotype in Adipose-Derived Stem Cells Cells, 10(11).
PMID: 34831345
S Roumelioti et al. (2021), Association between Biomarkers of Oxidative Stress and Inflammation with Cardiac Necrosis and Heart Failure in Non-ST Segment Elevation Myocardial Infarction Patients and Various Degrees of Kidney Function Oxidative Medicine and Cellular Longevity, 2021(0):3090120.
PMID: 34760045
Species: Human
Sample Types: Plasma

C Griffen et al. (2021), Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: A randomised, double-blind, placebo-controlled trial Experimental gerontology, 0(0):111651.
PMID: 34896568
Species: Human
Sample Types: Cell Culture Supernates

K Chaumonnot et al. (2021), The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress Cell Death Disease, 2021;12(1):114.
PMID: 33483465
Species: Human
Sample Types: Plasma

S Li et al. (2021), Alteration of immune profiles is associated with pulmonary function and symptoms in patients with chronic obstructive pulmonary disease Molecular Medicine Reports, 24(5).
PMID: 34435653
Species: Human
Sample Types: Serum

Z Song et al. (2021), Metformin attenuates post-epidural fibrosis by inhibiting the TGF-&beta1/Smad3 and HMGB1/TLR4 signaling pathways Journal of Cellular and Molecular Medicine, 0(0).
PMID: 33611840
Species: Human
Sample Types: Conditioned Media

GL Perrucci et al. (2020), Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients Cells, 9(1).
PMID: 31936351
Species: Human
Sample Types: Plasma

M Laggner et al. (2020), Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products Stem Cell Res Ther, 11(1):9.
PMID: 31900195
Species: Human
Sample Types: Cell Culture Supernates

YY Liu et al. (2020), Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA Chin. Med. J., 0(6):679-686.
PMID: 32068606
Species: Human
Sample Types: Cell Culture Supernates

YJ Liang et al. (2020), Statin inhibits large hepatitis delta antigen-Smad3 -twist-mediated epithelial-to-mesenchymal transition and hepatitis D virus secretion J. Biomed. Sci., 27(1):65.
PMID: 32434501
Species: Human
Sample Types: Cell Culture Supernates

Y Liu et al. (2020), Long Non-Coding RNA MACC1-AS1 Is Involved in Distant Recurrence of Hepatocellular Carcinoma After Surgical Resection Med. Sci. Monit., 26(0):e921175.
PMID: 32267834
Species: Human
Sample Types: Serum

G Giannelli et al. (2020), Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-&betaRI inhibitor galunisertib PLoS ONE, 15(3):e0222259.
PMID: 32210440
Species: Human
Sample Types: Cell Culture Supernates

N Igarashi et al. (2020), Involvement of autotaxin in the pathophysiology of elevated intraocular pressure in Posner-Schlossman syndrome Sci Rep, 10(1):6265.
PMID: 32286414
Species: Human
Sample Types: Cell Culture Supernates

HH Park et al. (2020), TGF-&beta secreted by human umbilical cord blood-derived mesenchymal stem cells ameliorates atopic dermatitis by inhibiting secretion of TNF-&alpha and IgE Stem Cells, 0(0).
PMID: 32277785
Species: Human
Sample Types: Tissue Lysates

B Butts et al. (2020), Reduced Left Atrial Emptying Fraction and Chymase Activation in Pathophysiology of Primary Mitralï¿½Regurgitation JACC Basic Transl Sci, 5(2):109-122.
PMID: 32140620
Species: Human
Sample Types: Plasma

Y Kong et al. (2020), LINK-A lncRNA is upregulated in osteosarcoma and regulates migration, invasion and stemness of osteosarcoma cells Oncol Lett, 19(4):2832-2838.
PMID: 32218837
Species: Human
Sample Types: Cell Culture Supernates

I Janulaityt et al. (2020), In Vivo Allergen-Activated Eosinophils Promote Collagen I and Fibronectin Gene Expression in Airway Smooth Muscle Cells via TGF-&beta1 Signaling Pathway in Asthma Int J Mol Sci, 21(5).
PMID: 32155894
Species: Human
Sample Types: Cell Culture Supernates

J Li et al. (2020), N6-Methyladenosine Regulates the Expression and Secretion of TGF&beta1 to Affect the Epithelial-Mesenchymal Transition of Cancer Cells Cells, 9(2).
PMID: 31991845
Species: Human
Sample Types: Cell Culture Supernates

S Valle et al. (2020), Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells Nat Commun, 11(1):5265.
PMID: 33067432
Species: Human
Sample Types: Serum

MA Hannappe et al. (2020), Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients Sci Rep, 10(1):16718.
PMID: 33028913
Species: Human
Sample Types: BALF

R Li et al. (2020), Preconditioning mesenchymal stromal cells with flagellin enhances the anti?inflammatory ability of their secretome against lipopolysaccharide?induced acute lung injury Molecular Medicine Reports, 0(0).
PMID: 32945411
Species: Equine
Sample Types: Cell Culture Supernates

K Fukuda et al. (2020), Optimal activation methods for maximizing the concentrations of platelet-derived growth factor-BB and transforming growth factor-&beta1 in equine platelet-rich plasma J. Vet. Med. Sci., 0(0).
PMID: 32814750
Species: Human
Sample Types: Cell Culture Supernates

T Phillips et al. (2020), Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa J Dermatol Sci, 0(0).
PMID: 33143962
Species: Human
Sample Types: Cell Culture Supernates

J Koh et al. (2020), Regulatory (FoxP3+) T cells and TGF-&beta predict the response to anti-PD-1 immunotherapy in patients with non-small cell lung cancer Sci Rep, 10(1):18994.
PMID: 33149213
Species: Human
Sample Types: Plasma

R Muñóz-Godí et al. (2020), Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression Mediators of Inflammation, 2020(0):1678780.
PMID: 33488292
Species: Human
Sample Types: Serum

AN Burska et al. (2020), Dynamics of Early Signalling Events during Fracture Healing and Potential Serum Biomarkers of Fracture Non-Union in Humans J Clin Med, 9(2).
PMID: 32054088
Species: Human
Sample Types: Fecal Supernates

YJ Yang et al. (2020), Probiotics-Containing Yogurt Ingestion and H. pylori Eradication Can Restore Fecal Faecalibacterium prausnitzii Dysbiosis in H. pylori-Infected Children Biomedicines, 8(6).
PMID: 32492860
Species: Human
Sample Types: Cell Culture Supernates

C Corbet et al. (2020), TGFbeta2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells Nat Commun, 11(1):454.
PMID: 31974393
Species: Mouse
Sample Types: Cell Culture Supernates

H Quan et al. (2020), Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium Molecules, 25(11).
PMID: 32532146
Species: Human
Sample Types: Serum

G Merckx et al. (2020), Angiogenic Effects of Human Dental Pulp and Bone Marrow-Derived Mesenchymal Stromal Cells and their Extracellular Vesicles Cells, 9(2).
PMID: 32012900
Species: Human
Sample Types: Serum

MO Kutuk et al. (2020), Cytokine expression profiles in Autism spectrum disorder: A multi-center study from Turkey Cytokine, 133(0):155152.
PMID: 32563959
Species: Rat
Sample Types: Serum

X Liu et al. (2020), Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation-mediated autophagy signaling pathway Cell Death Dis, 11(6):454.
PMID: 32532964
Species: Rat
Sample Types: Tissue Homogenates

Y Shi et al. (2020), Delayed treatment with an autophagy inhibitor 3-MA alleviates the progression of hyperuricemic nephropathy Cell Death Dis, 11(6):467.
PMID: 32555189
Species: Human
Sample Types: Tissue Homogenates

O Pogozhykh et al. (2020), Repeated Freezing Procedures Preserve Structural and Functional Properties of Amniotic Membrane for Application in Ophthalmology Int J Mol Sci, 21(11).
PMID: 32512889
Species: Human
Sample Types: Cell Lysates

SC Notodihard et al. (2019), Comparison of the efficacy of cryopreserved human platelet lysate and refrigerated lyophilized human platelet lysate for wound healing Regen Ther, 10(0):1-9.
PMID: 30525065
Species: Human
Sample Types: Cell Culture Supernates

K Ishii et al. (2019), Pirfenidone, an Anti-Fibrotic Drug, Suppresses the Growth of Human Prostate Cancer Cells by Inducing G? Cell Cycle Arrest J Clin Med, 8(1).
PMID: 30621175
Species: Human
Sample Types: Cell Culture Supernates

ZJ Liang et al. (2019), Ginsenoside Rg1 Accelerates Paracrine Activity and Adipogenic Differentiation of Human Breast Adipose-Derived Stem Cells in a Dose-Dependent Manner In Vitro Cell Transplant, 0(0):9636897198256.
PMID: 30675799
Species: Human
Sample Types: Serum

H Man et al. (2019), Expression of a Novel Long Noncoding RNA (lncRNA), GASL1, is Downregulated in Patients with Intracranial Aneurysms and Regulates the Proliferation of Vascular Smooth Muscle Cells In Vitro Med. Sci. Monit., 25(0):1133-1139.
PMID: 30742604
Species: Human
Sample Types: Cell Culture Supernates

V Miceli et al. (2019), Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems Stem Cells Int, 2019(0):7486279.
PMID: 30911299
Species: Human
Sample Types: Cell Culture Supernates

EJ Im et al. (2019), Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A Nat Commun, 10(1):1387.
PMID: 30918259
Species: Human
Sample Types: Urine

D Kostic et al. (2019), The role of renal biomarkers to predict the need of surgery in congenital urinary tract obstruction in infants J Pediatr Urol, 0(0).
PMID: 30979613
Species: Human
Sample Types: Peritoneal Fluid

KN Khan et al. (2019), Association between FOXP3+ regulatory T-cells and occurrence of peritoneal lesions in women with ovarian endometrioma and dermoid cysts Reprod. Biomed. Online, 0(0).
PMID: 30981619
Species: Human
Sample Types: Cell Culture Supernates

S Morscheid et al. (2019), Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-? and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells Int J Mol Sci, 20(10).
PMID: 31137788
Species: Human
Sample Types: Plasma

C Schutz et al. (2019), Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study PLoS Med., 16(7):e1002840.
PMID: 31276515
Species: Human
Sample Types: Cell Lysates

A Almadori et al. (2019), Stem cell enriched lipotransfer reverses the effects of fibrosis in systemic sclerosis PLoS ONE, 14(7):e0218068.
PMID: 31314805
Species: Human
Sample Types: Cell Culture Supernates

R García-Roc et al. (2019), Cervical cancer cells produce TGF-?1 through the CD73-adenosine pathway and maintain CD73 expression through the autocrine activity of TGF-?1 Cytokine, 118(0):71-79.
PMID: 30301599
Species: Human
Sample Types: Cell Culture Supernates

M Suto et al. (2019), A Potato Peel Extract Stimulates Type I Collagen Synthesis via Akt and ERK Signaling in Normal Human Dermal Fibroblasts Biol. Pharm. Bull., 42(9):1510-1516.
PMID: 31474711
Species: Human
Sample Types: Cell Culture Supernates

S Fujimoto et al. (2019), KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF- Î²2 suppression Regen Ther, 11(0):249-257.
PMID: 31538102
Species: Equine
Sample Types: Platelet-Poor Plasma

SRT Seidel et al. (2019), Does Double Centrifugation Lead to Premature Platelet Aggregation and Decreased TGF-beta1 Concentrations in Equine Platelet-Rich Plasma? Vet Sci, 6(3).
PMID: 31438534
Species: Human
Sample Types: Cell Culture Supernates

Q Li et al. (2019), Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition PLoS ONE, 14(10):e0223724.
PMID: 31600351
Species: Bovine
Sample Types: Milk Whey

S Holvoet et al. (2019), Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-beta-Enriched Formula Nutrients, 11(9).
PMID: 31540231
Species: Human
Sample Types: Cell Culture Supernates

P Zhao et al. (2019), Response gene to complement 32 expression in macrophages augments paracrine stimulation-mediated colon cancer progression Cell Death Dis, 10(10):776.
PMID: 31601783
Species: Human
Sample Types: Cell Lysates

J Manokawinc et al. (2019), Intermittent compressive force promotes osteogenic differentiation in human periodontal ligament cells by regulating the transforming growth factor-beta pathway Cell Death Dis, 10(10):761.
PMID: 31591384
Species: Human
Sample Types: Tissue Homogenates

J Li et al. (2019), TGFbeta-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis Nat Commun, 10(1):2795.
PMID: 31243287
Species: Human
Sample Types: Cell Culture Supernates

A Shakurnia et al. (2019), Sugarcane molasses enhances TGF-beta secretion and FOXP3 gene expression by Bifidobacterium Animalis Subsp. Lactis stimulated PBMCs of Ulcerative Colitis patients Complement Ther Med, 47(0):102210.
PMID: 31780030
Species: Human
Sample Types: Serum

FG Scurt et al. (2019), Systemic Inflammation Precedes Microalbuminuria in Diabetes Kidney Int Rep, 4(10):1373-1386.
PMID: 31701047
Species: Human
Sample Types: Cell Culture Supernates

Z Wang et al. (2019), Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo Heliyon, 5(10):e02739.
PMID: 31720476
Species: Equine
Sample Types: Plasma

MA de Laat et al. (2019), An investigation of the equine epidermal growth factor system during hyperinsulinemic laminitis PLoS ONE, 14(12):e0225843.
PMID: 31805097
Species: Human
Sample Types: Wound Fluid

JP Hodde et al. (2019), Characterization of the local wound environment following treatment of chronic leg ulcers with SIS wound matrix J Tissue Viability, 0(0).
PMID: 31866230
Species: Human
Sample Types: Plasma

K Moideen et al. (2019), Heightened systemic levels of anti-inflammatory cytokines in pulmonary tuberculosis and alterations following anti-tuberculosis treatment Cytokine, 127(0):154929.
PMID: 31811994
Species: Human
Sample Types: Cell Culture Supernates

S Kajiwara et al. (2019), Castration-induced stromal remodeling disrupts the reconstituted prostate epithelial structure Lab. Invest., 0(0).
PMID: 31857695
Species: Human
Sample Types: Cell Culture Supernates

A Oppezzo et al. (2019), Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia J. Clin. Invest., 0(0).
PMID: 31877112
Species: Human
Sample Types: Serum

H Park et al. (2019), The prognostic role of soluble TGF-beta and its dynamics in unresectable pancreatic cancer treated with chemotherapy Cancer Med, 0(0).
PMID: 31701645
Species: Human
Sample Types: Aqueous Humor

S NikhalaShr et al. (2019), Lowered Decorin With Aberrant Extracellular Matrix Remodeling in Aqueous Humor and Tenon's Tissue From Primary Glaucoma Patients Invest. Ophthalmol. Vis. Sci., 60(14):4661-4669.
PMID: 31725165
Species: Human
Sample Types: Cell Culture Supernates

YC Ou et al. (2019), Fibronectin Promotes Cell Growth and Migration in Human Renal Cell Carcinoma Cells Int J Mol Sci, 20(11).
PMID: 31181623
Species: Human
Sample Types: Cell Culture Supernates

Z Horváth et al. (2019), Tumor-specific inhibitory action of decorin on different hepatoma cell lines Cell. Signal., 62(0):109354.
PMID: 31271881
Species: Human
Sample Types: Extracellular Vesicles

M Borghesan et al. (2019), Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3 Cell Rep, 27(13):3956-3971.e6.
PMID: 31242426
Species: Human
Sample Types: Cell Culture Supernates

X Zang et al. (2019), Adipose-derived stem cells prevent the onset of bisphosphonate-related osteonecrosis of the jaw through transforming growth factor ?-1-mediated gingival wound healing Stem Cell Res Ther, 10(1):169.
PMID: 31196208
Species: Human
Sample Types: Cell Culture Supernates

M Nakao et al. (2019), Characteristic differences of cell sheets composed of mesenchymal stem cells with different tissue origins Regen Ther, 11(0):34-40.
PMID: 31193157
Species: Rabbit
Sample Types: Platelet Rich Fibrin

MY Bai et al. (2018), Relationships of Age and Sex with Cytokine Content and Distribution in Human Platelet Fibrin Gels Sci Rep, 8(1):10642.
PMID: 30006555
Species: Human
Sample Types: Plasma

T Hanada et al. (2018), Suppressive regulatory T cells and latent transforming growth factor-?-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis Reprod. Biol. Endocrinol., 16(1):9.
PMID: 29391020
Species: Human
Sample Types: Cell Culture Supernates

YK Noh et al. (2018), Induction of chondrogenesis of human placenta-derived mesenchymal stem cells via heparin-grafted human fibroblast derived matrix Biomater Res, 22(0):12.
PMID: 29760942
Species: Human
Sample Types: Aqueous Humor

GM Tosi et al. (2018), TGF-? concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration Sci Rep, 8(1):8053.
PMID: 29795291
Species: Human
Sample Types: Cell Culture Supernates

CC Tsai et al. (2018), Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts Sci Rep, 8(1):7276.
PMID: 29739987
Species: Human
Sample Types: Cell Culture Supernates

B Chen et al. (2018), Overexpression of Klotho Inhibits HELF Fibroblasts SASP-related Protumoral Effects on Non-small Cell Lung Cancer Cells J Cancer, 9(7):1248-1258.
PMID: 29675106
Species: Human
Sample Types: Cell Culture Supernates

VR Barnhouse et al. (2018), Myoferlin regulates epithelial cancer cell plasticity and migration through autocrine TGF-?1 signaling Oncotarget, 9(27):19209-19222.
PMID: 29721195
Species: Human
Sample Types: Pleural Effusion

J Budna et al. (2018), Enhanced Suppressive Activity of Regulatory T Cells in the Microenvironment of Malignant Pleural Effusions J Immunol Res, 2018(0):9876014.
PMID: 29785404
Species: Human
Sample Types: Serum

AE Stanciu et al. (2018), The role of pro-fibrotic biomarkers in paroxysmal and persistent atrial fibrillation Cytokine, 103(0):63-68.
PMID: 29324263
Species: Human
Sample Types: Serum

S Stanilova et al. (2018), Transforming growth factor-?1 gene promoter -509C/T polymorphism in association with expression affects colorectal cancer development and depends on gender PLoS ONE, 13(8):e0201775.
PMID: 30071009
Species: Human
Sample Types: Cell Culture Supernates

P Li et al. (2018), Maelstrom directs myeloid-derived suppressor cells to promote esophageal squamous cell carcinoma progression via activation of the Akt1/RelA/IL-8 signaling pathway Cancer Immunol Res, 0(0).
PMID: 30082413
Species: Human
Sample Types: Cell Culture Supernates

F Agostini et al. (2018), 1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures PLoS ONE, 13(9):e0203048.
PMID: 30188924
Species: Human
Sample Types: Plasma

S Pauly et al. (2018), The effect of autologous platelet rich plasma on tenocytes of the human rotator cuff BMC Musculoskelet Disord, 19(1):422.
PMID: 30497435
Species: Human
Sample Types: Plasma

FN Osuji et al. (2018), The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects J. Biomed. Sci., 25(1):88.
PMID: 30501642
Species: Porcine
Sample Types: Plasma

T Huang et al. (2018), Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs Vet. Res., 49(1):121.
PMID: 30541630
Species: Human
Sample Types: Plasma

F Miao et al. (2018), LncRNA HAND2-AS1 inhibits non-small cell lung cancer migration, invasion and maintain cell stemness through the interactions with TGF-?1 Biosci. Rep., 0(0).
PMID: 30509963
Species: Human
Sample Types: BALF

JM Forel et al. (2018), Transforming Growth Factor-?1 in predicting early lung fibroproliferation in patients with acute respiratory distress syndrome PLoS ONE, 13(11):e0206105.
PMID: 30395619
Species: Human
Sample Types: Cell Culture Supernates

D Vu?eti? et al. (2018), Flow cytometry analysis of platelet populations: usefulness for monitoringthe storage lesion in pooled buffy-coat platelet concentrates Blood Transfus, 16(1):83-92.
PMID: 28166864
Species: Human
Sample Types: Cell Culture Supernates

G Wang et al. (2018), Human amniotic epithelial cells regulate osteoblast differentiation through the secretion of TGF?1 and microRNA-34a-5p Int. J. Mol. Med., 41(2):791-799.
PMID: 29207015
Species: Human
Sample Types: Cell Culture Supernates

A Tominaga et al. (2018), Quality assessment of cellular and tissue-based products using liquid chromatography-tandem mass spectrometry Biochem. Biophys. Res. Commun., 0(0).
PMID: 29305868
Species: Human
Sample Types: Serum
Applications: ELISA (Standard)

EO Curvo et al. (2018), Correlation of transforming growth factor-?1 and tumour necrosis factor levels with left ventricular function in Chagas disease Mem. Inst. Oswaldo Cruz, 113(4):e170440.
PMID: 29513876
Species: Human
Sample Types: Platelet Extracts
Applications: ELISA Capture

JM Sipes et al. (2018), Thrombospondins: Purification of human platelet thrombospondin-1 Methods Cell Biol., 143(0):347-369.
PMID: 29310787
Species: Human
Sample Types: Cell Culture Supernates
Applications: ELISA Capture

A Aldhahrani et al. (2018), The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis Laryngoscope, 0(0).
PMID: 29399801
Species: Human
Sample Types: Cell Culture Supernates

A Merdrignac et al. (2018), A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma Hepatol Commun, 2(3):254-269.
PMID: 29507901
Species: Human
Sample Types: Serum

MA Abu El Mak et al. (2018), The Role of Signal Transducer and Activator of Transcription 5 and Transforming Growth Factor-Beta 1 in Hepatic Fibrosis Induced by Chronic Hepatitis C Virus Infection in Egyptian Patients Med Princ Pract, 0(0).
PMID: 29402841
Species: Human
Sample Types: Cell Culture Supernates

BN Lourenço et al. (2018), CD44v6 increases gastric cancer malignant phenotype by modulating adipose stromal cell-mediated ECM remodeling Integr Biol (Camb), 0(0).
PMID: 29450424
Species: Human
Sample Types: Serum

N Sarabon et al. (2018), Acute effect of different concentrations of cayenne pepper cataplasm on sensory-motor functions and serum levels of inflammation-related biomarkers in healthy subjects Eur J Transl Myol, 28(1):7333.
PMID: 29686821
Species: Human
Sample Types: Serum

Y Okada et al. (2018), Regulation of transforming growth factor is involved in the efficacy of combined 5-fluorouracil and interferon alpha-2b therapy of advanced hepatocellular carcinoma Cell Death Discov, 4(0):42.
PMID: 29560281
Species: Human
Sample Types: Plasma

T Astuti et al. (2018), The levels of pro-fibrotic cytokines in pulmonary tuberculosis with minimal and extensive lesions Lung India, 35(3):204-208.
PMID: 29697076
Species: Human
Sample Types: Plasma

T Oka et al. (2018), Changes in fatigue, autonomic functions, and blood biomarkers due to sitting isometric yoga in patients with chronic fatigue syndrome Biopsychosoc Med, 12(0):3.
PMID: 29643935
Species: Human
Sample Types: Cell Culture Supernates

C Zhang et al. (2018), Photodynamic therapy induces antifibrotic alterations in primary human vocal fold fibroblasts Laryngoscope, 0(0).
PMID: 29668038
Species: Human
Sample Types: Cell Culture Supernates

D Bayik et al. (2018), Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages Front Immunol, 9(0):608.
PMID: 29632539
Species: Human
Sample Types: Cell Culture Supernates

GA Howe et al. (2017), MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2 PLoS ONE, 12(10):e0185619.
PMID: 28977001
Species: Human
Sample Types: Cell Culture Supernates

KC Clark et al. (2017), Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome Stem Cell Res Ther, 8(1):69.
PMID: 28320483
Species: Human
Sample Types: Tissue Secretion

M Laube et al. (2017), Inflammatory Mediators in Tracheal Aspirates of Preterm Infants Participating in a Randomized Trial of Inhaled Nitric Oxide PLoS ONE, 12(1):e0169352.
PMID: 28046032
Species: Human
Sample Types: Serum

Z Meng et al. (2017), High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection BMC Gastroenterol, 17(1):6.
PMID: 28061755
Species: Human
Sample Types: Serum

Y Zhang et al. (2017), Platelet-rich plasma induces post-natal maturation of immature articular cartilage and correlates with LOXL1 activation Sci Rep, 7(1):3699.
PMID: 28623328
Species: Human
Sample Types: Plasma

J Lu et al. (2017), Increased expression of latent TGF-?-binding protein 4 affects the fibrotic process in scleroderma by TGF-?/SMAD signaling Lab. Invest, 0(0).
PMID: 28263294
Species: Primate
Sample Types: Serum

JD Coplan et al. (2017), Effects of Acute Confinement Stress-induced Hypothalamic-Pituitary Adrenal Axis Activation and Concomitant Peripheral and Central Transforming Growth Factor-?1 Measures in Nonhuman Primates Chronic Stress (Thousand Oaks), 1(0).
PMID: 28393139
Species: Human
Sample Types: Cell Culture Supernates

S Gopal et al. (2017), Fibronectin-guided migration of carcinoma collectives Nat Commun, 8(0):14105.
PMID: 28102238
Species: Human
Sample Types: Cell Lysates

GL Gravina et al. (2017), The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models Tumour Biol., 39(6):1010428317695.
PMID: 28639900
Species: Human
Sample Types: Cell Culture Supernates

W Katagiri et al. (2017), Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells Maxillofac Plast Reconstr Surg, 39(1):8.
PMID: 28405581
Species: Human
Sample Types: Urine

L Tylicki et al. (2017), Aliskiren reduces albuminuria after kidney transplantation Acta Biochim. Pol., 0(0).
PMID: 28455996
Species: Human
Sample Types: Bone Marrow Fluid

K Tao et al. (2017), Effects of combined rAAV-mediated TGF-? and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates J Exp Orthop, 4(1):4.
PMID: 28176272
Species: Human
Sample Types: Cell Lysates

M Bernardi et al. (2017), The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro J Transl Med, 15(1):90.
PMID: 28460641
Species: Human
Sample Types: Tears

X Wang et al. (2017), Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery Mol. Vis., 23(0):275-285.
PMID: 28465659
Species: Human
Sample Types: Plasma

E Peyster et al. (2017), Inflammation and Arterial Stiffness in Chronic Kidney Disease: Findings From the CRIC Study Am. J. Hypertens., 30(4):400-408.
PMID: 28391349
Species: Human
Sample Types: Plasma

B Shen et al. (2017), Preparing Platelet-Rich Plasma with Whole Blood Harvested Intraoperatively During Spinal Fusion Med. Sci. Monit., 23(0):3578-3584.
PMID: 28734116
Species: Human
Sample Types: Tissue Homogenates

YY Go et al. (2017), Differential effects of amnion and chorion membrane extracts on osteoblast-like cells due to the different growth factor composition of the extracts PLoS ONE, 12(8):e0182716.
PMID: 28797129
Species: Human
Sample Types: Serum

N Quillinan et al. (2017), Multiplex serum protein analysis reveals potential mechanisms and markers of response to hyperimmune caprine serum in systemic sclerosis Arthritis Res. Ther, 19(1):45.
PMID: 28270187
Species: Human
Sample Types: Cell Culture Supernates

G Vazquez Ro et al. (2017), Estradiol promotes breast cancer cell migration via recruitment and activation of neutrophils Cancer Immunol Res, 0(0).
PMID: 28159748
Species: Human
Sample Types: Serum

Y Wang et al. (2017), Predictive Value of Serum IFN-? inducible Protein-10 and IFN-?/IL-4 Ratio for Liver Fibrosis Progression in CHB Patients Sci Rep, 7(0):40404.
PMID: 28067328
Species: Equine
Sample Types: Plasma

G Hauschild et al. (2017), Short term storage stability at room temperature of two different platelet-rich plasma preparations from equine donors and potential impact on growth factor concentrations BMC Vet. Res, 13(1):7.
PMID: 28056978
Species: Human
Sample Types: Cell Culture Supernates

A Rey-Rico et al. (2017), rAAV-mediated overexpression of TGF-? via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model Int J Nanomedicine, 12(0):6985-6996.
PMID: 29033566
Species: Human
Sample Types: Cell Culture Supernates

Q Cao et al. (2017), MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression J. Exp. Clin. Cancer Res, 36(1):29.
PMID: 28193228
Species: Human
Sample Types: Cell Culture Supernates

H Kusumoto et al. (2017), Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma Cancer Sci., 108(3):528-535.
PMID: 28004467
Species: Human
Sample Types: Plasma

D Capper et al. (2017), Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine Int J Mol Sci, 18(5).
PMID: 28481241
Species: Human
Sample Types: Plasma

VR Ribeiro et al. (2017), Association between cytokine profile and transcription factors produced by T cells subsets in early and late-onset preeclampsia Immunology, 0(0).
PMID: 28502089
Species: Human
Sample Types: Cell Culture Supernates

J Liu et al. (2017), Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells Exp Ther Med, 13(4):1447-1455.
PMID: 28413491
Species: Human
Sample Types: Cell Culture Supernates

Q Li et al. (2017), A sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes Nat Commun, 8(0):15166.
PMID: 28466868
Species: Human
Sample Types: Aqueous Humor

GM Tosi et al. (2017), HTRA1 and TGF-?1 Concentrations in the Aqueous Humor of Patients With Neovascular Age-Related Macular Degeneration Invest. Ophthalmol. Vis. Sci, 58(1):162-167.
PMID: 28114575
Species: Human
Sample Types: Serum

P Komolmit et al. (2017), Vitamin D supplementation improves serum markers associated with hepatic fibrogenesis in chronic hepatitis C patients: A randomized, double-blind, placebo-controlled study Sci Rep, 7(1):8905.
PMID: 28827788
Species: Canine
Sample Types: Serum

S Neumann et al. (2017), TGF-?1 serum concentrations and receptor expressions in the lens capsular of dogs with diabetes mellitus Open Vet J, 7(1):12-15.
PMID: 28180095
Species: Human
Sample Types: Plasma

T Mehta et al. (2017), Higher plasma transforming growth factor (TGF)-? is associated with kidney disease in older community dwelling adults BMC Nephrol, 18(1):98.
PMID: 28327102
Species: Human
Sample Types: Cell Culture Supernates

L Dou et al. (2017), Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis Sci Rep, 7(1):7300.
PMID: 28779163
Species: Human
Sample Types: Serum

NA Johdi et al. (2017), Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps Cytokine, 99(0):35-42.
PMID: 28689023
Species: Human
Sample Types: Serum

G Schmalz et al. (2017), MMP-8 and TIMP-1 are associated to periodontal inflammation in patients with rheumatoid arthritis under methotrexate immunosuppression - First results of a cross-sectional study J Microbiol Immunol Infect, 0(0).
PMID: 28919284
Species: Human
Sample Types: Cell Culture Supernates

P Åström et al. (2017), The interplay of matrix metalloproteinase-8, transforming growth factor-?1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma Br. J. Cancer, 117(7):1007-1016.
PMID: 28772283
Species: Human
Sample Types: Plasma

Y Liu et al. (2017), Suppressive role of diallyl trisul?de in the activated platelet-mediated hematogenous metastasis of MDA-MB-231 human breast cancer cells Int. J. Mol. Med., 39(6):1516-1524.
PMID: 28440392
Species: Human
Sample Types: Cell Culture Supernates

(2016), Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves EBioMedicine, 10(0):282-90.
PMID: 27394642
Species: Human
Sample Types: Cell Culture Supernates

Anne Fischer-Ni (2016), Overcoming the bottleneck of platelet lysate supply in large-scale clinical expansion of adipose-derived stem cells: A comparison of fresh versus three types of platelet lysates from outdated buffy coat-derived platelet concentrates Cytotherapy, 0(0).
PMID: 27887865
Species: Human
Sample Types: Whole Cells

Warren C Plaisted (2016), Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis PLoS ONE, 11(6):e0157620.
PMID: 27310015
Species: Human
Sample Types: Plasma

Chun Li (2016), Circulating Fibrocytes Are Increased in Neonates with Bronchopulmonary Dysplasia PLoS ONE, 11(6):e0157181.
PMID: 27309347
Species: Human
Sample Types: Cell Culture Supernates

(2016), Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling Sci Rep, 6(0):29029.
PMID: 27374240
Species: Human
Sample Types: Plasma

(2016), Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells J Exp Clin Cancer Res, 35(1):147.
PMID: 27643489
Species: Human
Sample Types: Cell Culture Supernates

RJ Moritz et al. (2016), Macrophage TGF-?1 and the Proapoptotic Extracellular Matrix Protein BIGH3 Induce Renal Cell Apoptosis in Prediabetic and Diabetic Conditions Int J Clin Med, 7(7):496-510.
PMID: 28149671
Species: Human
Sample Types: Serum

El?bieta Radzikowsk (2016), Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia Adv Clin Exp Med, 25(5):871-878.
PMID: 28028949
Species: Human
Sample Types: Cell Culture Supernates

(2016), Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis JCI Insight, 1(20):e90954.
PMID: 27942596
Species: Human
Sample Types: Cell Culture Supernates

J Bennett et al. (2016), Tacrolimus Modulates TGF-? Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells J Clin Med, 5(5).
PMID: 27128949
Species: Human
Sample Types: Plasma

Gorka Orive (2016), Biological effects of plasma rich in growth factors (PRGF) on human endometrial fibroblasts Eur. J. Obstet. Gynecol. Reprod. Biol., 206(0):125-130.
PMID: 27693932
Species: Human
Sample Types: Cell Culture Supernates

(2016), The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-? signaling Cell Death Dis, 7(11):e2443.
PMID: 27809299
Species: Human
Sample Types: Cell Lysates

W Qin et al. (2016), Exosomes in Human Breast Milk Promote EMT Clin Cancer Res, 0(0).
PMID: 27060153
Species: Human
Sample Types: Cell Culture Supernates

(2016), Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke Stem Cells Int, 2016(0):6104780.
PMID: 27840648
Species: Human
Sample Types: Urine

Ma?gorzata Pa?czyk-To (2016), Urine interleukin-6, interleukin-8 and transforming growth factor ?1 in infants with urinary tract infection and asymptomatic bacteriuria Cent Eur J Immunol, 41(3):260-267.
PMID: 27833443
Species: Human
Sample Types: Tissue Homogenates

Ingrid C Weel (2016), Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia PLoS ONE, 11(6):e0157584.
PMID: 27315098
Species: Human
Sample Types: Cell Culture Supernates

O Freynet et al. (2016), Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study Respir Res, 17(1):36.
PMID: 27044262
Species: Human
Sample Types: Platelet Rich Plasma (PRP)

Hideo Masuki (2016), Growth factor and pro-inflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factors (PRGF), advanced platelet-rich fibrin (A-PRF), and concentrated growth factors (CGF) Int J Implant Dent, 2(1):19.
PMID: 27747711
Species: Human
Sample Types: Serum

(2016), Alterations in the Fecal Microbiota of Patients with HIV-1 Infection: An Observational Study in A Chinese Population Sci Rep, 6(0):30673.
PMID: 27477587
Species: Human
Sample Types: Serum

(2016), Transforming Growth Factor-?1 as a Predictor for the Development of Hepatocellular Carcinoma: A Nested Case-Controlled Study EBioMedicine, 0(0).
PMID: 27614396
Species: Human
Sample Types: Serum

Tostes G et al. (2016), Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study. Diabetol Metab Syndr, 8(0):1.
PMID: 26734075
Species: Human
Sample Types: Cell Culture Supernates

Driver J et al. (2015), Alcohol inhibits osteopontin-dependent transforming growth factor-beta1 expression in human mesenchymal stem cells. J Biol Chem, 290(16):9959-73.
PMID: 25713073
Species: Human
Sample Types: Plasma

Gupta J et al. (2015), Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study. PLoS ONE, 10(4):e0124772.
PMID: 25909952
Species: Human
Sample Types: Cell Culture Supernates

Maris P et al. (2015), Asporin Is a Fibroblast-Derived TGF-beta1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Med, 12(9):e1001871.
PMID: 26327350
Species: Human
Sample Types: Cell Culture Supernates

Yamada A et al. (2015), Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE, 10(3):e0120192.
PMID: 25799450
Species: Human
Sample Types: Cell Culture Supernates

Mizuuchi Y et al. (2015), Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition. Lab Invest, 95(2):193-206.
PMID: 25418581
Species: Mouse
Sample Types: Cell Culture Supernates

Zhao D et al. (2015), WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features. BMC Gastroenterol, 15(0):173.
PMID: 26652024
Species: Human
Sample Types: Serum

Mouzaki A et al. (2015), Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation. PLoS ONE, 10(8):e0135434.
PMID: 26317430
Species: Human
Sample Types: Tissue Homogenates

Si Y et al. (2015), Transforming Growth Factor Beta (TGF-beta) Is a Muscle Biomarker of Disease Progression in ALS and Correlates with Smad Expression. PLoS ONE, 10(9):e0138425.
PMID: 26375954
Species: Human
Sample Types: Plasma

Wang et al. (2014), The clinical correlation of regulatory T cells and cyclic adenosine monophosphate in enterovirus 71 infection. PLoS ONE, 9(7):e102025.
PMID: 25010330
Species: Human
Sample Types: Cell Culture Supernates

Fujimura K et al. (2014), Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice. PLoS ONE, 9(4):e94373.
PMID: 24747517
Species: Human
Sample Types: Cell Culture Supernates

Nakamura T et al. (2014), Angiopoietin-like protein 2 induced by mechanical stress accelerates degeneration and hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis. PLoS ONE, 9(1):e85542.
PMID: 24465594
Species: Human
Sample Types: Cell Culture Supernates

Iudicone et al. (2014), Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells. J Transl Med, 12(0):28.
PMID: 24467837
Species: Human
Sample Types: Cell Culture Supernates

Tu B et al. (2014), Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-beta/Smad2/3 pathway. Exp Cell Res, 320(1):164-73.
PMID: 24183998
Species: Human
Sample Types: Cell Culture Supernates

Tulley S et al. (2014), Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-beta signaling. J Biol Chem, 289(22):15280-96.
PMID: 24727589
Species: Human
Sample Types: Serum

Tang Y et al. (2014), Different subsets of macrophages in patients with new onset tuberculous pleural effusion. PLoS ONE, 9(2):e88343.
PMID: 24520370
Species: Human
Sample Types: Serum

Pastor-Clerigues A et al. (2014), Anti-inflammatory and anti-fibrotic profile of fish oil emulsions used in parenteral nutrition-associated liver disease. PLoS ONE, 9(12):e115404.
PMID: 25502575
Young V et al. (2014), The peritoneum is both a source and target of TGF-beta in women with endometriosis. PLoS ONE, 9(9):e106773.
PMID: 25207642
Species: Human
Sample Types: Cell Culture Supernates

Shi G et al. (2014), Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients. Eur J Immunol, 44(2):420-30.
PMID: 24155161
Species: Human
Sample Types: Cell Culture Supernates

Berardis S et al. (2014), Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells. PLoS ONE, 9(1):e86137.
PMID: 24516514
Species: Human
Sample Types: Cell Culture Supernates

Jiang Y et al. (2014), The role of TGF-beta1-miR-21-ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells. Br J Cancer, 111(4):772-80.
PMID: 24992582
Species: Human
Sample Types: Cell Culture Supernates

Chou M et al. (2014), Ex vivo expansion of bovine corneal endothelial cells in xeno-free medium supplemented with platelet releasate. PLoS ONE, 9(6):e99145.
PMID: 24945500
Alcaraz L et al. (2014), Tenascin-X promotes epithelial-to-mesenchymal transition by activating latent TGF-beta. J Cell Biol, 205(3):409-28.
PMID: 24821840
Species: Human
Sample Types: BALF

Chou C et al. (2014), The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia. BMC Pulm Med, 14(0):182.
PMID: 25409888
Species: Human
Sample Types: Cell Culture Supernates

Horie M et al. (2014), Differential knockdown of TGF-beta ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer. BMC Cancer, 14(0):580.
PMID: 25107280
Species: Human
Sample Types: Cell Culture Supernates

Santhekadur P et al. (2014), Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling. FEBS Open Bio, 4(0):353-61.
PMID: 24918049
Species: Human
Sample Types: Cell Culture Supernates

Krishnan G et al. (2014), Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity. Mol Cell Neurosci, 59(0):10-23.
PMID: 24418364
Species: Human
Sample Types: Cell Culture Supernates

Karagiannis G et al. (2014), Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins claudin-11 and occludin. Mol Oncol, 8(2):178-95.
PMID: 24268521
Species: Human
Sample Types: Cell Culture Supernates

Soria-Valles C et al. (2014), The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21. Oncogene, 33(23):3054-63.
PMID: 23851508
Species: Human
Sample Types: Plasma

Apinjoh T et al. (2014), Association of candidate gene polymorphisms and TGF-beta/IL-10 levels with malaria in three regions of Cameroon: a case-control study. Malar J, 13(0):236.
PMID: 24934404
Species: Human
Sample Types: Plasma

Necchi A et al. (2014), Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy. Br J Cancer, 110(1):26-33.
PMID: 24231947
Species: Human
Sample Types: Plasma

Armstrong A et al. (2013), Long-term survival and biomarker correlates of tasquinimod efficacy in a multicenter randomized study of men with minimally symptomatic metastatic castration-resistant prostate cancer. Clin Cancer Res, 19(24):6891-901.
PMID: 24255071
Species: Human
Sample Types: Plasma

Teichert T et al. (2013), Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study. PLoS ONE, 8(12):e83042.
PMID: 24340078
Species: Human
Sample Types: Cell Culture Supernates

Andre T et al. (2013), Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. PLoS ONE, 8(3):e59756.
PMID: 23555770
Species: Human
Sample Types: Cell Lysates

Barsotti M et al. (2013), Effect of platelet lysate on human cells involved in different phases of wound healing. PLoS ONE, 8(12):e84753.
PMID: 24386412
Species: Human
Sample Types: Plasma

Divella R et al. (2013), Circulating levels of transforming growth factor-betaeta (TGF-beta) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancer. Anticancer Res, 33(4):1491-7.
PMID: 23564790
Species: Human
Sample Types: Cell Culture Supernates

Pliyev B et al. (2013), Neutrophil microparticles modulate cytokine production by natural killer cells. Cytokine, 65(2):126-9.
PMID: 24355430
Species: Human
Sample Types: Cell Culture Supernates

Loubaki L et al. (2013), Co-culture of human bronchial fibroblasts and CD4+ T cells increases Th17 cytokine signature. PLoS ONE, 8(12):e81983.
PMID: 24349168
Species: Human
Sample Types: Cell Culture Supernates

Darakhshan S et al. (2013), Tranilast enhances the anti-tumor effects of tamoxifen on human breast cancer cells in vitro. J Biomed Sci, 20(0):76.
PMID: 24143895
Species: Rat
Sample Types: Cell Culture Supernates

Bialas A et al. (2013), TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement. Nat Neurosci, 16(12):1773-82.
PMID: 24162655
Species: Human
Sample Types: Cell Culture Supernates

Shinojima N et al. (2013), TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells. Cancer Res, 73(7):2333-44.
PMID: 23365134
Species: Human
Sample Types: Platelet Rich Plasma (PRP)

Peng Y et al. (2013), Platelet rich plasma clot releasate preconditioning induced PI3K/AKT/NFkappaB signaling enhances survival and regenerative function of rat bone marrow mesenchymal stem cells in hostile microenvironments. Stem Cells Dev, 22(24):3236-51.
PMID: 23885779
Species: Human
Sample Types: Cell Culture Supernates

Pontikoglou C et al. (2013), Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia. Stem Cells Dev, 22(9):1329-41.
PMID: 23249221
Species: Human
Sample Types: Serum

Qin W et al. (2013), Vitamin D favorably alters the cancer promoting prostaglandin cascade. Anticancer Res, 33(9):3861-6.
PMID: 24023320
Species: Human
Sample Types: Cell Culture Supernates

Lauzier A et al. (2012), Transglutaminase 2 cross-linking activity is linked to invadopodia formation and cartilage breakdown in arthritis. Arthritis Res. Ther., 14(4):R159.
PMID: 22762273
Species: Human
Sample Types: Platelet Poor Plasma

Anuradha R et al. (2012), Altered circulating levels of matrix metalloproteinases and inhibitors associated with elevated type 2 cytokines in lymphatic filarial disease. PLoS Negl Trop Dis, 6(6):e1681.
PMID: 22679524
Species: Human
Sample Types: Cell Culture Supernates

Kostopoulou F et al. (2012), Central role of SREBP-2 in the pathogenesis of osteoarthritis. PLoS ONE, 7(5):e35753.
PMID: 22662110
Species: Human
Sample Types: Milk

Qin W et al. (2012), Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy. BMC Cancer, 12(0):100.
PMID: 22436421
Species: Human
Sample Types: Cell Culture Supernates

Wei J et al. (2012), Hypoxia potentiates glioma-mediated immunosuppression. PLoS ONE, 6(1):e16195.
PMID: 21283755
Species: Human
Sample Types: Urine

Yang CC et al. (2012), Urinary neutrophil gelatinase-associated lipocalin is a potential biomarker for renal damage in patients with systemic lupus erythematosus. J. Biomed. Biotechnol., 2012(0):759313.
PMID: 22500106
Species: Human
Sample Types: Cell Culture Supernates

Bianchetti L et al. (2012), IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma. Biochem Biophys Res Commun, 426(1):116-21.
PMID: 22921786
Species: Human
Sample Types: Serum

Churchman SM et al. (2012), Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor. Clin. Exp. Rheumatol., 30(4):534-42.
PMID: 22704737
Species: Human
Sample Types: Cell Culture Supernates

Dupuy S et al. (2012), Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog., 8(1):e1002486.
PMID: 22253598
Species: Human
Sample Types: BALF

Quesnel C et al. (2012), Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury. Crit. Care Med., 40(1):21-8.
PMID: 21926612
Species: Human
Sample Types: Recombinant Protein

Ma W et al. (2011), Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J. Clin. Invest., 121(11):4548-66.
PMID: 22005303
Species: Human
Sample Types: Urine

Kim MJ et al. (2011), Oral cholecalciferol decreases albuminuria and urinary TGF-beta1 in patients with type 2 diabetic nephropathy on established renin-angiotensin-aldosterone system inhibition. Kidney Int., 80(8):851-60.
PMID: 21832985
Species: Human
Sample Types: Cell Culture Supernates

Robinson AP et al. (2011), Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor beta and Notch signaling. Stem Cells Dev., 20(2):289-300.
PMID: 20575640
Species: Canine
Sample Types: Cell Culture Supernates

Gregory PA et al. (2011), An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol. Biol. Cell, 22(10):1686-98.
PMID: 21411626
Species: Human
Sample Types: Cell Culture Supernates

Henriksson ML et al. (2011), Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion. Am. J. Pathol., 178(3):1387-94.
PMID: 21356388
Species: Human
Sample Types: Serum

Di Meglio P et al. (2011), The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans. PLoS ONE, 6(2):e17160.
PMID: 21364948
Species: Human
Sample Types: Cell Culture Supernates

Scheel C et al. (2011), Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell, 145(6):926-40.
PMID: 21663795
Species: Human
Sample Types: Cell Lysates

Rauch C et al. (2011), Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media. ALTEX, 28(4):305-16.
PMID: 22130485
Species: Human
Sample Types: Urine

Hu YY et al. (2010), Hydrochloride pioglitazone decreases urinary TGF-beta1 excretion in type 2 diabetics. Eur. J. Clin. Invest., 40(7):571-4.
PMID: 20482594
Species: Human
Sample Types: Cell Culture Supernates

Tso GH et al. (2010), Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells. Stem Cells, 28(5):939-54.
PMID: 20222014
Species: Human
Sample Types: Cell Culture Supernates

Ha CT et al. (2010), Human pregnancy specific beta-1-glycoprotein 1 (PSG1) has a potential role in placental vascular morphogenesis. Biol. Reprod., 83(1):27-35.
PMID: 20335639
Species: Human
Sample Types: Urine

Huan Y et al. (2010), Regulation of transforming growth factor-beta1 by insulin in prediabetic African Americans. Kidney Int., 78(3):318-24.
PMID: 20393450
Species: Human
Sample Types: Cell Culture Supernates

Liang X et al. (2010), Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Blood, 115(24):5041-52.
PMID: 20339095
Species: Human
Sample Types: Cell Culture Supernates

Ferreira MC et al. (2010), Involvement of regulatory T cells in the immunosuppression characteristic of patients with paracoccidioidomycosis. Infect. Immun., 78(10):4392-401.
PMID: 20643858
Species: Human
Sample Types: Milk

Holmlund U et al. (2010), Maternal country of origin, breast milk characteristics and potential influences on immunity in offspring. Clin. Exp. Immunol., 162(3):500-9.
PMID: 20942805
Species: Human
Sample Types: Cell Culture Supernates

Ramirez JM et al. (2010), Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. Eur. J. Immunol., 40(9):2450-9.
PMID: 20706985
Species: Human
Sample Types: Tissue Homogenates

Bachert C et al. (2010), Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J. Allergy Clin. Immunol., 126(5):962.
PMID: 20810157
Species: Human
Sample Types: Plasma

Quintas-Cardama A et al. (2009), Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis. J. Clin. Oncol., 27(28):4760-6.
PMID: 19720904
Species: Human
Sample Types: Cell Culture Supernates

Nold-Petry CA et al. (2009), Increased cytokine production in IL-18 receptor alpha-deficient cells is associated with dysregulation of suppressors of cytokine signaling (SOCS). J. Biol. Chem., 0(0).
PMID: 19592492
Species: Human
Sample Types: Plasma

Pitteri SJ et al. (2009), Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS ONE, 4(11):e7916.
PMID: 19936259
Species: Human
Sample Types: Cell Culture Supernates

Gomez D et al. (2009), Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J. Pathol., 218(1):131-42.
PMID: 19224541
Species: Human
Sample Types: Cell Culture Supernates

Farrow B et al. (2009), Tumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2. J. Surg. Res., 156(1):155-60.
PMID: 19592030
Species: Human
Sample Types: Nasal Lavage Fluid

Lee HS et al. (2009), Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis. Am. J. Respir. Crit. Care Med., 180(11):1056-67.
PMID: 19762561
Species: Human
Sample Types: Cell Culture Supernates

Margulis A et al. (2009), MMP dependence of fibroblast contraction and collagen production induced by human mast cell activation in a three-dimensional collagen lattice. Am. J. Physiol. Lung Cell Mol. Physiol., 296(2):L236-47.
PMID: 19060229
Species: Human
Sample Types: Cell Culture Supernates

Chase JC et al. (2009), Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Infect. Immun., 77(1):180-95.
PMID: 18981246
Species: Human
Sample Types: Cell Culture Supernates

Oh JY et al. (2009), Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells. Cytokine, 46(1):100-3.
PMID: 19223198
Species: Rabbit
Sample Types: Cell Culture Supernates

Gogly B et al. (2009), Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model. J. Mol. Cell. Cardiol., 47(2):296-303.
PMID: 19397914
Schirmer SH et al. (2009), Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans. J. Am. Coll. Cardiol., 53(23):2141-7.
PMID: 19497439
Species: Human
Sample Types: Cell Culture Supernates

Rojas A et al. (2008), The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer. Int. J. Cancer, 123(1):14-21.
PMID: 18425817
Species: Human
Sample Types: Cell Culture Supernates

Xu JW et al. (2008), Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor {beta} and expression of glycodelin in human endometrial epithelial cells. J. Endocrinol., 196(2):425-33.
PMID: 18252965
Species: Human
Sample Types: Platelet Poor Plasma

Kanter J et al. (2008), Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates. Clin. Cancer Res., 14(12):3942-7.
PMID: 18559616
Species: Human
Sample Types: Serum

Bolin P et al. (2008), Optimizing tacrolimus therapy in the maintenance of renal allografts: 12-month results. Transplantation, 86(1):88-95.
PMID: 18622283
Species: Human
Sample Types: Plasma

Shariat SF et al. (2008), Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Clin. Cancer Res., 14(12):3785-91.
PMID: 18559597
Species: Human
Sample Types: Cell Culture Supernates

Leone G et al. (2008), Amidic alginate hydrogel for nucleus pulposus replacement. J Biomed Mater Res A, 84(2):391-401.
PMID: 17618483
Species: Human
Sample Types: Cell Culture Supernates

Van Aarsen LA et al. (2008), Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer Res., 68(2):561-70.
PMID: 18199553
Species: Human
Sample Types: Cell Culture Supernates

Tabata T et al. (2008), Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production. Am. J. Pathol., 172(4):1127-40.
PMID: 18349127
Species: Human
Sample Types: Plasma

Liem-Moolenaar M et al. (2008), Pharmacodynamics and Pharmacokinetics of the Novel Thrombopoietin Mimetic Peptide RWJ-800088 in Humans. 84(0):481.
PMID: 19238653
Species: Human
Sample Types: Serum

Kim JY et al. (2008), Up-regulated macrophage migration inhibitory factor protects apoptosis of dermal fibroblasts in patients with systemic sclerosis. Clin. Exp. Immunol., 152(2):328-35.
PMID: 18355352
Species: Human
Sample Types: BALF

Pulichino AM et al. (2008), Identification of transforming growth factor beta1-driven genetic programs of acute lung fibrosis. Am. J. Respir. Cell Mol. Biol., 39(3):324-36.
PMID: 18403781
Species: Human
Sample Types: Cell Culture Supernates

Rocks N et al. (2008), ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo. Cancer Res., 68(22):9541-50.
PMID: 19010931
Species: Human
Sample Types: Serum

Koivisto H et al. (2007), Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis. Dig. Dis. Sci., 53(2):500-5.
PMID: 17597408
Species: Human
Sample Types: Cell Culture Supernates

Liotta F et al. (2007), Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells, 26(1):279-89.
PMID: 17962701
Species: Human
Sample Types: Cell Culture Supernates

Nazareth MR et al. (2007), Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells. J. Immunol., 178(9):5552-62.
PMID: 17442937
Species: Human
Sample Types: Vaginal Lavage Fluid

Keller MJ et al. (2007), PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity. AIDS, 21(4):467-76.
PMID: 17301565
Species: Human
Sample Types: Cell Culture Supernates

Yoo SA et al. (2007), Calcineurin modulates the catabolic and anabolic activity of chondrocytes and participates in the progression of experimental osteoarthritis. Arthritis Rheum., 56(7):2299-311.
PMID: 17599750
Species: Human
Sample Types: Cell Culture Supernates

Vidyarani M et al. (2007), 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis. Cytokine, 40(2):128-34.
PMID: 17911026
Species: Human
Sample Types: Cell Culture Supernates

Nagineni CN et al. (2007), Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. J. Cell. Physiol., 210(1):192-200.
PMID: 17013806
Species: Human
Sample Types: Serum

Chaigneau C et al. (2007), Serum biobank certification and the establishment of quality controls for biological fluids: examples of serum biomarker stability after temperature variation. Clin. Chem. Lab. Med., 45(10):1390-5.
PMID: 17635068
Species: Human
Sample Types: Cell Culture Supernates

Ao M et al. (2007), Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res., 67(9):4244-53.
PMID: 17483336
Species: Human
Sample Types: BALF

Barrera L et al. (2007), Functional diversity of T-cell subpopulations in subacute and chronic hypersensitivity pneumonitis. Am. J. Respir. Crit. Care Med., 177(1):44-55.
PMID: 17947613
Species: Human
Sample Types: Tissue Homogenates

Herrmann S et al. (2006), Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation. Bone, 39(5):1156-63.
PMID: 16863704
Species: Human
Sample Types: Cell Culture Supernates

Mesturini R et al. (2006), ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells. Eur. J. Immunol., 36(10):2601-12.
PMID: 17013990
Species: Human
Sample Types: Cell Culture Supernates

Pang L et al. (2006), Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities. J. Immunol., 176(6):3788-95.
PMID: 16517749
Species: Primate - Pan troglodytes (Chimpanzee)
Sample Types: Cell Culture Supernates

Manigold T et al. (2006), Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood, 107(11):4424-32.
PMID: 16478885
Species: Human
Sample Types: Cell Culture Supernates

Karrar A et al. (2006), Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Gut, 56(2):243-52.
PMID: 16840505
Species: Human
Sample Types: Tissue Homogenates

Ito M et al. (2006), Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node. J. Immunol., 176(9):5637-43.
PMID: 16622033
Species: Human
Sample Types: Cell Culture Supernates

Lee KY et al. (2006), Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kappaB pathway. Am. J. Respir. Cell Mol. Biol., 35(4):407-14.
PMID: 16690986
Species: Mouse
Sample Types: Cell Culture Supernates

Nakagome K et al. (2006), In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-beta in the lung. Thorax, 61(10):886-94.
PMID: 16809410
Species: Canine
Sample Types: Cell Culture Supernates

Liu HC et al. (2006), Albumin induces cellular fibrosis by upregulating transforming growth factor-beta ligand and its receptors in renal distal tubule cells. J. Cell. Biochem., 97(5):956-68.
PMID: 16267840
Species: Human
Sample Types: Plasma

Borrelli V et al. (2006), Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions. Surgery, 140(3):454-63.
PMID: 16934609
Species: Human
Sample Types: Cell Culture Supernates

Ehling A et al. (2006), The potential of adiponectin in driving arthritis. J. Immunol., 176(7):4468-78.
PMID: 16547285
Species: Human
Sample Types: Cell Culture Supernates

Skoberne M et al. (2006), The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 108(3):947-55.
PMID: 16614246
Species: Human
Sample Types: Cell Culture Supernates

Puxeddu I et al. (2005), The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J. Allergy Clin. Immunol., 117(1):103-10.
PMID: 16387592
Species: Human
Sample Types: Synovial Fluid

Pagura SM et al. (2005), Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men. J. Orthop. Res., 23(2):397-405.
PMID: 15734254
Species: Human
Sample Types: Cell Culture Supernates

Voo KS et al. (2005), Functional characterization of EBV-encoded nuclear antigen 1-specific CD4+ helper and regulatory T cells elicited by in vitro peptide stimulation. Cancer Res., 65(4):1577-86.
PMID: 15735048
Species: Rat
Sample Types: Tissue Homogenates

O&amp;apos;Bryan MK (2005), Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses. Am. J. Physiol. Regul. Integr. Comp. Physiol., 288(6):R1744-55.
PMID: 15661966
Species: Human
Sample Types: Urine

Szeto CC et al. (2005), Messenger RNA expression of target genes in the urinary sediment of patients with chronic kidney diseases. Nephrol. Dial. Transplant., 20(1):105-13.
PMID: 15561743
Species: Human
Sample Types: Serum

Huang JL et al. (2005), Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome. Microbes Infect., 7(3):427-36.
PMID: 15784184
Species: Porcine
Sample Types: Plasma

Waldow T et al. (2004), Attenuation of reperfusion-induced systemic inflammation by preconditioning with nitric oxide in an in situ porcine model of normothermic lung ischemia. Chest, 125(6):2253-9.
PMID: 15189949
Species: Rabbit
Sample Types: Plasma

Zhang CQ et al. (2004), Experimental study of the effect of platelet-rich plasma on osteogenesis in rabbit. Chin. Med. J., 117(12):1853-5.
PMID: 15603719
Species: Hamster
Sample Types: Intrapleural Fluid

Soga Y et al. (2004), Attenuation of adhesion formation after cardiac surgery with a chymase inhibitor in a hamster model. J. Thorac. Cardiovasc. Surg., 127(1):72-8.
PMID: 14752415
Species: Human
Sample Types: Seminal Plasma

Basu S et al. (2004), Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J. Androl., 25(2):250-4.
PMID: 14760011
Species: Human
Sample Types: Plasma

Chaiyaroj SC et al. (2004), Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria. Acta Trop., 89(3):319-27.
PMID: 14744558
Species: Human
Sample Types: Plasma

Flores L et al. (2004), Transforming growth factor beta at clinical onset of Type 1 diabetes mellitus. A pilot study. Diabet. Med., 21(8):818-22.
PMID: 15270783
Species: Human
Sample Types: Sponge Fluid

Kyriakides TR et al. (2004), The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation. Am. J. Pathol., 165(6):2157-66.
PMID: 15579457
Species: Human
Sample Types: Cell Culture Supernates

Saika S et al. (2004), Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice. Lab. Invest., 84(10):1245-58.
PMID: 15273699
Species: Porcine
Sample Types: Plasma

Blanaru JL et al. (2004), Dose response of bone mass to dietary arachidonic acid in piglets fed cow milk-based formula. Am. J. Clin. Nutr., 79(1):139-47.
PMID: 14684410
Species: Human
Sample Types: Colostrum

Ogawa J et al. (2004), Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants. Early Hum. Dev., 77(1):67-75.
PMID: 15113633
Species: Human
Sample Types: Cell Culture Supernates

Branski RC et al. (2004), Markers of wound healing in vocal fold secretions from patients with laryngeal pathology. Ann. Otol. Rhinol. Laryngol., 113(1):23-9.
PMID: 14763567
Species: Human
Sample Types: Cell Culture Supernates

Moseman EA et al. (2004), Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J. Immunol., 173(7):4433-42.
PMID: 15383574
Species: Human
Sample Types: BALF

Chen LL et al. (2004), Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects. Chest, 125(6):2328-35.
PMID: 15189958
Species: Human
Sample Types: Cell Culture Supernates

Deiva K et al. (2004), Fractalkine reduces N-methyl-d-aspartate-induced calcium flux and apoptosis in human neurons through extracellular signal-regulated kinase activation. Eur. J. Neurosci., 20(12):3222-32.
PMID: 15610155
Species: Human
Sample Types: Milk

Oddy WH et al. (2003), TGF-beta in human milk is associated with wheeze in infancy. J. Allergy Clin. Immunol., 112(4):723-8.
PMID: 14564350
Species: Human
Sample Types: Tissue Secretion

Verdolini K et al. (2003), Shifts in biochemical markers associated with wound healing in laryngeal secretions following phonotrauma: a preliminary study. Ann. Otol. Rhinol. Laryngol., 112(12):1021-5.
PMID: 14703104
Species: Mouse
Sample Types: Serum

Huaux F et al. (2003), Dual roles of IL-4 in lung injury and fibrosis. J. Immunol., 170(4):2083-92.
PMID: 12574379
Species: Human
Sample Types: Nasal Fluid

Ewbank PA et al. (2003), A double-blind, placebo-controlled immunotherapy dose-response study with standardized cat extract. J. Allergy Clin. Immunol., 111(1):155-61.
PMID: 12532112
Species: Rat
Sample Types: Serum

Chen YJ et al. (2003), Shock wave application enhances pertussis toxin protein-sensitive bone formation of segmental femoral defect in rats. J. Bone Miner. Res., 18(12):2169-79.
PMID: 14672352
Species: Human
Sample Types: Urine

Agarwal R et al. (2002), Add-on angiotensin II receptor blockade lowers urinary transforming growth factor-beta levels. Am. J. Kidney Dis., 39(3):486-92.
PMID: 11877567
Species: Human
Sample Types: Cell Culture Supernates

Luo XH et al. (2002), Progesterone upregulates TGF-b isoforms (b1, b2, and b3) expression in normal human osteoblast-like cells. Calcif. Tissue Int., 71(4):329-34.
PMID: 12154395
Species: Mouse
Sample Types: Whole Cells

Liu BY et al. (2002), Estrogen inhibition of PTH-stimulated osteoclast formation and attachment in vitro: involvement of both PKA and PKC. 141-147, 143(2):627-35.
PMID: 11796519
Species: Human
Sample Types: Nasal Fluid

Benson M et al. (2002), DNA microarray analysis of transforming growth factor-beta and related transcripts in nasal biopsies from patients with allergic rhinitis. Cytokine, 18(1):20-5.
PMID: 12090756
Species: Porcine
Sample Types: Hemofiltrates

Yekebas EF et al. (2002), Impact of different modalities of continuous venovenous hemofiltration on sepsis-induced alterations in experimental pancreatitis. Kidney Int., 62(5):1806-18.
PMID: 12371983
Species: Human
Sample Types: Tears

Lee JB et al. (2002), Comparison of TGF-beta1 in tears following laser subepithelial keratomileusis and photorefractive keratectomy. 6907, 18(2):130-4.
PMID: 11934200
Species: Porcine
Sample Types: Cell Lysates

Bracamonte MP et al. (2002), Ovariectomy increases mitogens and platelet-induced proliferation of arterial smooth muscle. Am. J. Physiol. Heart Circ. Physiol., 283(3):H853-60.
PMID: 12181111
Species: Bovine
Sample Types: Cell Lysates

Schmidt A et al. (2002), Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. 101211, 81(3):138-44.
PMID: 11998865
Species: Rabbit
Sample Types: Vitreous Humor

Oshima Y et al. (2002), Gene transfer of soluble TGF-beta type II receptor inhibits experimental proliferative vitreoretinopathy. Gene Ther., 9(18):1214-20.
PMID: 12215888
Species: Rat
Sample Types: Cell Culture Supernates

Truckenmiller ME et al. (2002), AF5, a CNS cell line immortalized with an N-terminal fragment of SV40 large T: growth, differentiation, genetic stability, and gene expression. Exp. Neurol., 175(0):318.
PMID: 12061863
Species: Bovine
Sample Types: Colostrum

Wei H et al. (2002), Stability and activity of specific antibodies against Streptococcus mutans and Streptococcus sobrinus in bovine milk fermented with Lactobacillus rhamnosus strain GG or treated at ultra-high temperature. Oral Microbiol. Immunol., 17(1):9-15.
PMID: 11860550
Species: Rat
Sample Types: N/A

D&amp;apos;Ovidio F (2002), Recipient intramuscular cotransfection of naked plasmid transforming growth factor beta1 and interleukin 10 ameliorates lung graft ischemia-reperfusion injury. J. Thorac. Cardiovasc. Surg., 124(2):259-69.
PMID: 12167785
Species: Rat
Sample Types: Peritoneal Fluid

Margetts PJ et al. (2001), Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function. J. Am. Soc. Nephrol., 12(10):2029-39.
PMID: 11562401
Species: Human
Sample Types: Cell Culture Supernates

Skutek M et al. (2001), Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts. Eur. J. Appl. Physiol., 86(1):48-52.
PMID: 11820322
Species: Human
Sample Types: Plasma

Landesberg R et al. (2000), Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation. J. Oral Maxillofac. Surg., 58(3):297.
PMID: 10716112
Species: Human
Sample Types: Serum

Otterness IG et al. (2000), An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline. Osteoarthr. Cartil., 8(3):180-5.
PMID: 10806045
Species: Human
Sample Types: Milk

Kalliomaki M et al. (1999), Transforming growth factor-beta in breast milk: a potential regulator of atopic disease at an early age. J. Allergy Clin. Immunol., 104(6):1251-7.
PMID: 10589009
Species: Human
Sample Types: Serum

Soubrier M et al. (1999), Growth factors and proinflammatory cytokines in the renal involvement of POEMS syndrome. Am. J. Kidney Dis., 34(4):633-8.
PMID: 10516342
Species: Human
Sample Types: Cell Culture Supernates

Fadok et al. (1998), Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest, 101(4):890-8.
PMID: 9466984
Species: Human
Sample Types: Serum

Chopra V et al. (1997), Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer. J. Cancer Res. Clin. Oncol., 123(3):167-72.
PMID: 9119882
Species: Canine
Sample Types: Cell Culture Supernates

Gu JW et al. (1997), Hypoxia-induced expression of VEGF is reversible in myocardial vascular smooth muscle cells. Am. J. Physiol., 273(2):H628-33.
PMID: 9277477
Species: Human
Sample Types: Cell Culture Supernates

Groux et al. (1997), A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature, 389(6652):737-42.
PMID: 9338786
Species: Mouse
Sample Types: Serum

De Lorenzo M et al. (0), Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesi32(9):1381-7.
PMID: 21665891
Species: Human
Sample Types: Cell Culture Supernates

Gao Y et al. (0), 'Psoriasis 1' reduces Tâ€‘lymphocyteâ€‘mediated inflammation in patients with psoriasis by inhibiting vitamin D receptorâ€‘mediated STAT4 inactivation. Int J Mol Me46(4):1538-1550.
PMID: 32945358
Species: Human
Sample Types: Cell Culture Supernates

Li Z et al. (0), ERK Regulates HIF1alpha-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer. Clin Cancer Re25(19):5947-5960.
PMID: 31285371

There are no citations that match your criteria.

Showing 1 - 10 of 391 citations Showing All

Customer Reviews for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA (20)

4.8 out of 5

20 customer ratings

5 stars

80%

4 stars

20%

3 stars

2 stars

1 star

Customer Images

(12)

See all customer images

Showing 1 - 5 of 20 reviews Showing All

Filter By:

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 03/17/2022
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: James Williams

Sample Tested: EDTA Plasma

Verified Customer | Posted 03/16/2022
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: Anonymous

Sample Tested: Serum-free Cell Culture Media

Verified Customer | Posted 01/10/2022
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: James AHODANTIN

Sample Tested: Plasmas from mice fed with HFD

Verified Customer | Posted 01/08/2022

Very sensitive and easy to use. I switched to the new version DB100C lately and both are quite similar. Good product
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: Anonymous

Sample Tested: EDTA Plasma

Verified Customer | Posted 09/01/2021
Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Name: Anonymous

Sample Tested: Serum-free Cell Culture Media

Verified Customer | Posted 07/02/2020
Human/Mouse/Rat/Porcine TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum-free Cell Culture Media

Verified Customer | Posted 06/26/2020
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Plasma

Verified Customer | Posted 02/28/2020

Easy to use, great results
Human TGF-beta 1 Quantikine ELISA Kit

Name: Evan Williams

Sample Tested: Plasma

Verified Customer | Posted 02/27/2020
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Blood mononuclear cells (PBMCs)

Verified Customer | Posted 01/16/2020
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Bone Extracts

Verified Customer | Posted 10/10/2019
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Peripheral blood mononuclear cells (PBMCs)

Verified Customer | Posted 07/08/2019
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Blood mononuclear cells (PBMCs)

Verified Customer | Posted 03/21/2019
Human TGF-beta 1 Quantikine ELISA Kit

Name: Ivan Luzardo

Sample Tested: Cell Culture Media

Verified Customer | Posted 12/11/2018
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 06/19/2018
Human TGF-beta 1 Quantikine ELISA Kit

Name: Jim Hsiao

Sample Tested: Mouse lung tissue homogenates,Mouse lung tissue

Verified Customer | Posted 11/29/2017

This result has been published in the PLoS ONE journal: https://doi.org/10.1371/journal.pone.0063798
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Serum

Verified Customer | Posted 07/21/2017
Human TGF-beta 1 Quantikine ELISA Kit

Name: Adam Guess

Sample Tested: Cell culture supernatant

Verified Customer | Posted 08/03/2016
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Muscle tissue

Verified Customer | Posted 06/20/2016

n/a
Human TGF-beta 1 Quantikine ELISA Kit

Name: Anonymous

Sample Tested: Bone Putty

Verified Customer | Posted 05/09/2016

There are no reviews that match your criteria.

Showing 1 - 5 of 20 reviews Showing All

FAQs for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Can samples be tested without activation in Human TGF-beta 1 Quantikine^® ELISA Kit, Catalog # DB100B, to determine levels of endogenously mature TGF-beta 1?

Catalog # DB100B is designed to measure TGF-beta 1 in activated serum and plasma samples. Activation releases TGF-beta 1 from latent TGF-beta 1 complexes. Internal tests with latent TGF-beta complex have demonstrated approximately 15% reactivity in the kit; however it is unclear whether this may be partially due to activation of latent TGF-beta 1 once added to the assay plate. Since the latent form of TGF-beta 1 may be significantly more abundant in serum and plasma, this cross-reactivity may make it difficult to measure low levels of active TGF-beta 1. Therefore, we recommend only using the kit to test activated serum and plasma samples for total TGF-beta 1 levels.

Product Documents for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

R&D Systems, Inc. a Bio-Techne Brand

Key Product Details

Customers also Viewed

Product Specifications for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Precision

Recovery

Linearity

Scientific Data Examples for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Preparation and Storage

Background: TGF-beta 1

Citations for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA (391)

Customer Reviews for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA (20)

Customer Images

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Human/Mouse/Rat/Porcine TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

Human TGF-beta 1 Quantikine ELISA Kit

FAQs for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Product Documents for Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

Product Datasheets

COA

Certificate of Analysis

SDS

Bio-Techne Brands