URB 602
Tocris Bioscience, part of Bio-Techne | Catalog # 6020
Non-competitive MAGL inhibitor
Discontinued Product
6020 has been discontinued.
View all Monoacylglycerol Lipase Inhibitors products.
Key Product Details
Description
Non-competitive MAGL inhibitor
Product Description
URB 602 is a non-competitive MAGL inhibitor. Exhibits selectivity for MAGL over FAAH, diacylglycerol lipase and COX2. Blocks 2-AG hydrolysis in rat brain slices. Enhances stress-induced analgesia in rats.Product Specifications
Molecular Weight
295.38
Formula
C19H21NO2
Storage
Store at +4°C
Purity
≥99% (HPLC)
Chemical Name
N-[1,1'-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
CAS Number
565460-15-3
PubChem ID
10979337
InChI Key
HHVUFQYJOSFTEH-UHFFFAOYSA-N
SMILES
O=C(OC1CCCCC1)NC2=CC=CC(C3=CC=CC=C3)=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.54 | 100 | |
| Ethanol | 29.54 | 100 |
Preparing Stock Solutions
for URB 602
The following data is based on the product molecular weight 295.38
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.39 mL | 16.93 mL | 33.85 mL |
| 5 mM | 0.68 mL | 3.39 mL | 6.77 mL |
| 10 mM | 0.34 mL | 1.69 mL | 3.39 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Makara Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus. Nat.Neurosci. 2005 PMID: 16116451
- Hohmann An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 PMID: 15973410
Product Specific Notices for URB 602
For research use only
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