BOP-JF646
Tocris Bioscience, part of Bio-Techne | Catalog # 6997
Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable
Discontinued Product
6997 has been discontinued.
View all Fluorescent Integrins Probes products.
Key Product Details
Description
Red fluorescent dual α9β1/α4β1 integrin inhibitor comprising BOP conjugated to Janelia Fluor® 646; fluorogenic; photostable
Product Description
BOP-JF646 is a fluorescent dual α9β1/α4β1 integrin inhibitor. Comprises BOP (Cat. No. 6047) conjugated to Janelia Fluor® 646 (Cat. No. 6148). Fluorogenic: fluoresces only once bound to integrins, enabling hassle-free no-wash experiments. Bright and photostable, enabling live cell tracking of integrin receptors over long time-course experiments. Excitation maximum = 655 nm; emission maximum = 672 nm.Scientific Data Images for BOP-JF646
Application of BOP-JF549 in Immortalized Human Keratinocyte Cells.
Immortalized human keratinocytes expressing a GFP-tagged alpha4 integrin were incubated with 10 μm BOP-Janelia Fluor® 568. Cells were incubated at 37°C and imaged using Nikon A1R confocal microscope. Scale bar = 10 μm.Image kindly provided by Willow Hight-Warburton; Kings College London.Optical Data
| Emission Color | Red |
| Brightness | |
| λabs | 655 nm |
| λem | 672 nm |
| Closest Laser line | 647 nm |
| Application | Flow Cytometry, Confocal Microscopy, Super Resolution Microscopy (SRM) |
Spectra Viewer
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectra Viewer
Product Specifications
Molecular Weight
1090.30
Formula
C57H59N9O10SSi
Storage
Store at -20°C
Purity
≥90% (HPLC)
Chemical Name
2-(3-(Azetidin-1-ium-1-ylidene)-7-(azetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)-5-(((1-((3R,5S)-5-(((S)-1-carboxy-2-(4-((pyrrolidine-1-carbonyl)oxy)phenyl)ethyl)carbamoyl)-1-(phenylsulfonyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methyl)carbamoyl)benzoate
InChI Key
NHBQNNGTILNQPL-HXFFEZBUSA-N
SMILES
OC([C@@H](NC([C@@H]1C[C@@H](N2C=C(CNC(C3=CC=C(C([O-])=O)C(C(C4=CC=C(N5CCC5)C=C4[Si]6(C)C)=C(C=C/7)C6=CC7=[N+]8CCC\8)=C3)=O)N=N2)CN1S(=O)(C9=CC=CC=C9)=O)=O)CC%10=CC=C(C=C%10)OC(N%11CCCC%11)=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Product Specific Notices for BOP-JF646
For research use only
Loading...
Loading...