TLR11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56742

Discontinued Product
NB100-56742 has been discontinued. View all TLR11 products.

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Western Blot, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all TLR11 Antibodies »

Product Specifications

Immunogen

A synthetic peptide within amino acid residues 911-926 (CEQLKRRLSKAGQERD) of mouse TLR11 (Genbank accession no. NP_991388) was used as immunogen.

Specificity

Immunizing peptide will block the mouse TLR11 band in western blotting.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for TLR11 Antibody

Western Blot: TLR11 Antibody [NB100-56742]

Western Blot: TLR11 Antibody [NB100-56742]

Western Blot: TLR11 Antibody [NB100-56742] - WB analysis of TLR11 in mouse testis lysate in A) the absence and B) presence of blocking peptide and rat testis lysate in C) the absence and D) presence of blocking peptide using at 3 ug/ml.
Flow Cytometry: TLR11 Antibody [NB100-56742]

Flow Cytometry: TLR11 Antibody [NB100-56742]

Flow Cytometry: TLR11 Antibody [NB100-56742] - Analysis using the FITC conjugate of NB100-56742. Staining of TLR11 in the TLR11 stable cell line using this antibody at 1 ug/10^6 cells (green represents vector control, red represents TLR11 antibody).
Western Blot: TLR11 Antibody [NB100-56742]

Western Blot: TLR11 Antibody [NB100-56742]

Western Blot: TLR11 Antibody [NB100-56742] - Western blot analysis of TLR11 in mouse RAW cell lysate using TLR11 antibody at 2 ug/ml.
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Applications for TLR11 Antibody

Application
Recommended Usage

Flow Cytometry

0.5-1 ug/10-6 cells

Western Blot

1-3 ug/ml
Application Notes
The approx. 32 kDa band may be a proteolytic degradation product of TLR11.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: TLR11

Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

Long Name

Toll-like Receptor 11

Alternate Names

Gm287

Entrez Gene IDs

239081 (Mouse); 498491 (Rat)

Gene Symbol

TLR11

UniProt

NP_991388

Additional TLR11 Products

Product Documents for TLR11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for TLR11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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