PTGER2/3 Antibody (3F12) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66718

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-66718
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # 3F12

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PTGER2/3 Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human PTGER2 and PTGER3 receptor protein and mouse myeloma cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Applications for PTGER2/3 Antibody (3F12) - BSA Free

Application
Recommended Usage

Western Blot

5-10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PTGER2/3

Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. EP3 receptors are 365-425 amino acid proteins. There are currently 4 known isoforms of EP3 receptors named EP3A, 3B, 3C and 3D. EP3 receptors are involved in water absorption, gastric acid secretion, uterine contraction, neurotransmitter release and the hydrolysis of fat cells (lipolysis) and also act as a mediator of neural inflammation.

Alternate Names

EP2, EP3, EP3-I, EP3-II, EP3-III, EP3-IV, PGE receptor EP2 subtype, PGE receptor, EP3 subtype, PGE2 receptor EP2 subtype, PGE2 receptor EP3 subtype, prostaglandin E receptor 2 (subtype EP2), 53kDa, prostaglandin E receptor 3 (subtype EP3), prostaglandin E2 receptor EP2 subtype, prostaglandin E2 receptor EP3 subtype, prostaglandin receptor (PGE-2), Prostanoid EP2 receptor, Prostanoid EP3 receptor, PTGER2;Ptger-ep2

UniProt

P43116

Additional PTGER2/3 Products

Product Documents for PTGER2/3 Antibody (3F12) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PTGER2/3 Antibody (3F12) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.