pan RhO/RAC/CDC42 Antibody (3L74) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29740

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-29740-0.025ml
NBP2-29740
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Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 3L74

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all pan RhO/RAC/CDC42 Antibodies »

Product Specifications

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 73-104 of human Rho (-A, -B, -C), with two terminal lysines added to increase peptide solubility.

Reactivity Notes

Human, Rat

Specificity

Recognizes Rho (-A, -B, -C).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Relevant Entrez Gene Numbers: NM_001664

Scientific Data Images for pan RhO/RAC/CDC42 Antibody (3L74) - Azide and BSA Free

Western Blot: pan RhO/RAC/CDC42 Antibody (3L74) [NBP2-29740]

Western Blot: pan RhO/RAC/CDC42 Antibody (3L74) [NBP2-29740]

Western Blot: pan RhO/RAC/CDC42 Antibody (3L74) [NBP2-29740] - HL-60 cell lysate was probed with anti-Rho (-A, -B, -C), clone 3L74 (1:2000 dilution). Arrow indicates Rho (-A, -B, -C) (~22kDa).

Applications for pan RhO/RAC/CDC42 Antibody (3L74) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.02M phosphate buffer, pH 7.6, 0.25M NaCl, and 30% glycerol.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: pan RhO/RAC/CDC42

pan RhO/RAC/CDC42 is encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.

Alternate Names

h12, oncogene RHO H12, ras homolog gene family, member A, Rho cDNA clone 12, RHO12, RhoA, RHOH12ARH12ARHAAplysia ras-related homolog 12, small GTP binding protein RhoA, transforming protein RhoA

UniProt

P61586 (Human)

Additional pan RhO/RAC/CDC42 Products

Product Documents for pan RhO/RAC/CDC42 Antibody (3L74) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for pan RhO/RAC/CDC42 Antibody (3L74) - Azide and BSA Free

Relevant Entrez Gene Numbers: NM_001664

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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