Musashi-1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1759

Discontinued Product
NB100-1759 has been discontinued. View all Musashi-1 products.

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Rat

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Musashi-1 Antibodies »

Product Specifications

Immunogen

Reacts with residues 5-21 [APQPGLASPDSPHDPCK] of the human, mouse and rat Musashi 1 protein.

Reactivity Notes

Reacts with human, rat, and mouse Musashi 1 protein.

Specificity

Musashi 1 - Neuronal Stem Cell Marker

Marker

Neuronal Stem Cell Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Musashi-1 Antibody - BSA Free

Western Blot: Musashi-1 AntibodyBSA Free [NB100-1759]

Western Blot: Musashi-1 AntibodyBSA Free [NB100-1759]

Western Blot: Musashi-1 Antibody [NB100-1759] - Detection of Musashi-1 protein in 10 ug of rat neural stem cell lysate (lane 1) and normal human brain lysate (lane 2) with Musashi-1 antibody NB100-1759 at a dilution of 1:500.
Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody - BSA Free [NB100-1759]

Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody - BSA Free [NB100-1759]

Immunocytochemistry/Immunofluorescence: Musashi-1 Antibody [NB100-1759] - Staining with Musashi polyclonal antibody (1:100 dilution) shows Musashi (green) staining on neural rosettes (human). Nuclei are counterstained blue (DAPI). Cells were fixed with 4 percent PFA. No antigen retrieval was done.
Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody - BSA Free [NB100-1759]

Immunocytochemistry/ Immunofluorescence: Musashi-1 Antibody - BSA Free [NB100-1759]

Immunocytochemistry/Immunofluorescence: Musashi-1 Antibody [NB100-1759] - Musashi-positive cells stained with Musashi antibody (1:150 dilution) in the ventricular zone of E14.5 mouse medulla. Image taken at 200x magnification. The sections were 4% PFA fixed, paraffin-embedded and cut at 5 microns.

Applications for Musashi-1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:500
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 24006477)

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Musashi-1

Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia. It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.

Alternate Names

MSI1, Musashi1

Entrez Gene IDs

4440 (Human); 17690 (Mouse); 259272 (Rat)

Gene Symbol

MSI1

Additional Musashi-1 Products

Product Documents for Musashi-1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Musashi-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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