Laminin S/Laminin beta 2 Antibody (CL2979) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-42387

Novus Biologicals, part of Bio-Techne
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NBP2-42387-25ul
NBP2-42387
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL2979

Format

BSA Free

Concentration

1 mg/ml

View all Laminin S Antibodies »

Product Specifications

Immunogen

This antibody was developed using a recombinant protein derived from P55268, with the exact immunogen sequence remaining proprietary.

Reactivity Notes

Expected to cross react based on sequence identity: Rat (82%), Mouse (83%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for Laminin S/Laminin beta 2 Antibody (CL2979) - BSA Free

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Immunohistochemistry-Paraffin: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387] - Staining in human heart muscle and tonsil tissues. Corresponding LAMB2 RNA-seq data are presented for the same tissues.
Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387] - Analysis of purified human recombinant Laminin-421, Laminin-521, Laminin-332 and Laminin-111.
Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387]

Western Blot: Laminin S/Laminin beta 2 Antibody (CL2979) [NBP2-42387] - Analysis in human lung tissue.
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Applications for Laminin S/Laminin beta 2 Antibody (CL2979) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Laminin S

The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.

Long Name

Laminin, beta 2

Alternate Names

LAMB2, Laminin beta 2

Gene Symbol

LAMB2

UniProt

P55268 (Human)

Additional Laminin S Products

Product Documents for Laminin S/Laminin beta 2 Antibody (CL2979) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Laminin S/Laminin beta 2 Antibody (CL2979) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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