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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG2B Clone # 1060003

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Human KA1/GRIK containing peptide
Accession # Q16099

Specificity

Detects human KA1/GRIK in direct ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

CoraFluor(TM) 1, amine reactive

CoraFluor(TM) 1, thiol reactive

For more information, please see our CoraFluor(TM) TR-FRET technology flyer.

Scientific Data Images for KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [CoraFluor™ 1]

KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [CoraFluor™ 1]

Product Feature: CoraFluor Probes for TR-FRET

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

Applications for KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [CoraFluor™ 1]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: KA1/GRIK4

The GRIK4 gene encodes a glutamate receptor KA-1 protein that is 956 amino acids long, 107 kDA and functions in the major excitatory neurotransmitter in the central nervous system (CNS) by activation of ligand-gated ion channels and G protein-coupled membrane receptors. GRIK4 participate in the neuroactive ligand-receptor interaction, glutamatergic synapse, activation of calcium-permeable kainate receptors, and transmission across chemical synapses. It is known to mainly interact with the GRIK2 gene. Researchers have investigated the role of GRIK4 in bipolar disorder, carcinoma, schizophrenia, parkinson's disease, neuronitis and medulloblastoma.

Long Name

Glutamate Receptor KA1

Alternate Names

EAA1, GluK4, GRIK4

Additional KA1/GRIK4 Products

Product Documents

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KA1/GRIK4/Glutamate Receptor KA1 Antibody (1060003) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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