Human Integrin alphaL/CD11a APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB3595A
Discontinued Product
FAB3595A has been discontinued.
View all Integrin alpha L/CD11a products.
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # 345913
Product Specifications
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin alphaL
Tyr26-Met1089 (Tyr660Ile)
Accession # CAA68747
Tyr26-Met1089 (Tyr660Ile)
Accession # CAA68747
Specificity
Detects human Integrin alphaL in Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Human Integrin alphaL/CD11a APC-conjugated Antibody
Detection of Integrin alphaL/CD11a in Human Peripheral Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human Integrin aL/CD11a APC-conjugated Monoclonal Antibody (Catalog # FAB3595A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human Integrin alphaL/CD11a APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha L/CD11a
Integrin subunit alphaL/CD11a is a 180 kDa type I TM glycoprotein that interacts only with Integrin beta2/CD18 to form LFA-1, a leukocyte adhesion protein which binds endothelial cell ICAM. Human Integrin alphaL contains a 1064 aa extracellular domain (ECD), a 20 aa TM sequence and a 58 aa cytoplasmic domain. The ECD contains seven repeats that form a beta-propeller structure and one inserted vWA domain (I domain) containing a metal ion-dependent adhesion site (MIDAS). Human and mouse Integrin alphaL ECD share 74% aa identity. A second isoform has a 53 aa insert in the ECD.
Alternate Names
CD11a, ITGAL, LFA-1 alpha, Ly-15, Ly-21
Gene Symbol
ITGAL
UniProt
Additional Integrin alpha L/CD11a Products
Product Documents for Human Integrin alphaL/CD11a APC-conjugated Antibody
Product Specific Notices for Human Integrin alphaL/CD11a APC-conjugated Antibody
For research use only
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