Skip to main content

HLA Class I Antibody (MEM-123) [Alexa Fluor™ Plus 405]

Novus Biologicals, part of Bio-Techne | Catalog # NB500-505AFP405

Novus Biologicals, part of Bio-Techne
Discontinued Product
NB500-505AFP405 has been discontinued. View all HLA Class I products.

Key Product Details

Species Reactivity

Human, Bovine, Primate

Applications

ELISA, Flow Cytometry, Immunoprecipitation, CyTOF-ready

Label

Alexa Fluor Plus 405

Antibody Source

Monoclonal Mouse IgG3 Clone # MEM-123

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

COS-7 African green monkey kidney cells

Specificity

This antibody (clone MEM-123) reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. This antibody completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks This antibody MEM-G/9.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Applications for HLA Class I Antibody (MEM-123) [Alexa Fluor™ Plus 405]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HLA Class I

HLA CLass I is involved in the presentation of foreign antigens to the immune system. This antibody is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders. This antibody is also suitable as a positive control for HLA tissue typing and crossmatching.

Long Name

Class I Human Leukocyte Antigen

Alternate Names

HLA-A, HLA-ABC

Gene Symbol

HLA-A

Additional HLA Class I Products

Product Documents for HLA Class I Antibody (MEM-123) [Alexa Fluor™ Plus 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for HLA Class I Antibody (MEM-123) [Alexa Fluor™ Plus 405]



This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...