GABA Transporter 2 Antibody - Azide Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-61098

Novus Biologicals, part of Bio-Techne
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NB100-61098
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GABA Transporter 2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P31646

Specificity

Specific for endogenous levels of the ~82 kDa GABA Transporter 2 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

82 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit GABA Transporter 2 Antibody - Azide Free (NB100-61098) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for GABA Transporter 2 Antibody - Azide Free

Western Blot: GABA Transporter 2 Antibody [NB100-61098]

Western Blot: GABA Transporter 2 Antibody [NB100-61098]

Western Blot: GABA Transporter 2 Antibody [NB100-61098] - Analysis of mouse whole brain lysate showing specific immunolabeling of the ~67 kDa GAT-2 protein.

Applications for GABA Transporter 2 Antibody - Azide Free

Application
Recommended Usage

Immunohistochemistry

1:100-1:200

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:100-200

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol

Format

Azide Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: GABA Transporter 2

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).

Long Name

Sodium- and chloride-dependent GABA transporter 2

Alternate Names

GAT-2, GAT2, SLC6A13

Entrez Gene IDs

171163 (Rat)

Gene Symbol

SLC6A13

UniProt

P31646 (Rat)

Additional GABA Transporter 2 Products

Product Documents for GABA Transporter 2 Antibody - Azide Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for GABA Transporter 2 Antibody - Azide Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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