FOXL2 Antibody (CL12762) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44386

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Clone # CL12762

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all FOXL2 Antibodies »

Product Specifications

Immunogen

This antibody was generated using a synthetic peptide of P58012, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3

Scientific Data Images for FOXL2 Antibody (CL12762) - Azide and BSA Free

FOXL2 Antibody (CL12762) - Azide and BSA Free Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Analysis in human ovary and liver tissues using NBP3-44386 antibody. Corresponding FOXL2 RNA-seq data are presented for the same tissues.
FOXL2 Antibody (CL12762) - Azide and BSA Free Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Staining of human fallopian tube shows weak to moderate nuclear positivity in stromal cells.
FOXL2 Antibody (CL12762) - Azide and BSA Free Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Immunohistochemistry-Paraffin: FOXL2 Antibody [NBP3-44386]

Staining of human ovarian cancer (granulosa cell tumor) shows moderate to strong nuclear positivity in tumor cells.
View 4 more images

Applications for FOXL2 Antibody (CL12762) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FOXL2

There are 2 forms of the blepharophimosis/ptosis/epicanthus inversus syndrome. In one form, called type I, eyelid abnormalities are associated with ovarian failure. In the second type, called type II, only the eyelid defects are found. Both types map to 3q23. Crisponi et al. (2001) refined the physical mapping of the BPES critical region and positionally cloned a novel, putative winged helix/forkhead transcription factor gene, FOXL2, in which they found mutations to produce truncated proteins in type I families and larger proteins in type II. Consistent with an involvement in those tissues, FOXL2 was selectively expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles; in adult humans, it appeared predominantly in the ovary.

Long Name

Forkhead Box L2

Alternate Names

BPES, BPES1, PFRK, PINTO, POF3

Gene Symbol

FOXL2

Additional FOXL2 Products

Product Documents for FOXL2 Antibody (CL12762) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FOXL2 Antibody (CL12762) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.