Cytochrome P450 3A7 Antibody (C2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42129

Novus Biologicals, part of Bio-Techne
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NBP3-42129
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Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # C2

Format

BSA Free

Concentration

1 mg/ml

View all Cytochrome P450 3A7 Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Human Cytochrome P450 3A7 (Uniprot#: P24462; Pro344-Asp497 (Uniprot#: P24462)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Novus Biologicals Mouse Cytochrome P450 3A7 Antibody (C2) - BSA Free (NBP3-42129) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for Cytochrome P450 3A7 Antibody (C2) - BSA Free

Cytochrome P450 3A7 Antibody (C2)

Immunohistochemistry-Paraffin: Cytochrome P450 3A7 Antibody (C2) [NBP3-42129] -

Immunohistochemistry-Paraffin: Cytochrome P450 3A7 Antibody (C2) [NBP3-42129] - DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 20ug/ml NBP3-42129

Applications for Cytochrome P450 3A7 Antibody (C2) - BSA Free

Application
Recommended Usage

Immunohistochemistry

5-30ug/mL

Immunohistochemistry-Paraffin

5-30ug/mL

Western Blot

0.5-3ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS, pH7.4, 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cytochrome P450 3A7

The Cytochrome P450 (P450) family of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as NADPH and P450 reductase. There are over 200 cDNA®s which encode P450 protein. Epoxygenases are those P450 proteins which metabolize AA to epoxyeicosatrienoic acid (EETs) and w-hydroxylases are those P450 proteins which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). 20-HETE is converted from AA by the 4A family of P450 proteins which includes at least 8 different, though closely related isoforms. 4A1, 4A2, & 4A3 have been cloned from liver, kidney and testis and have been detected in renal, hepatic & brain microvessels.

Alternate Names

Aryl hydrocarbon hydroxylase, CP37, CYPIIIA7, cytochrome P450, Cytochrome P450 3A7, family 3, Flavoprotein linked monooxygenase, Microsomal monooxygenase, P450 HFLA, polypeptide 7, subfamily A, subfamily IIIA, Xenobiotic monooxygenase

Additional Cytochrome P450 3A7 Products

Product Documents for Cytochrome P450 3A7 Antibody (C2) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cytochrome P450 3A7 Antibody (C2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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