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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rat IgG2B Clone # 347608

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

E. coli-derived recombinant human CNP
Lys24-Cys126
Accession # P23582

Specificity

Detects the Pro form of human CNP (amino acids 24-126) in direct ELISAs and Western blots. Does not detect the CNP29 peptide (amino acids 98‑126). In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ANP precursor or rhBNP precursor is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2B

Applications for CNP/NPPC Antibody (347608) [DyLight 488]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CNP

CNP belongs to the natriuretic peptide hormone family which also includes ANP and BNP. CNP modulates cGMP-mediated proliferation and differentiation in a wide variety of tissues through interactions with its receptor, ANPRB. CNP promotes vasorelaxation and vascular remodeling. It is upregulated in damaged vascular endothelium.

Long Name

C-type Natriuretic Peptide

Alternate Names

NPPC

Gene Symbol

NPPC

Additional CNP Products

Product Documents for CNP/NPPC Antibody (347608) [DyLight 488]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CNP/NPPC Antibody (347608) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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