Anti-PAR Polyclonal Antibody (Rabbit)
R&D Systems, part of Bio-Techne | Catalog # 4336-BPC-100
Discontinued Product
4336-BPC-100 has been discontinued.
An alternative/replacement product is available:
4335-MC-100. View all PAR/pADPr products.
Key Product Details
Species Reactivity
Validated:
Multi-Species
Cited:
Human, Mouse, Rat, Avian - Chicken, Drosophila, Insect - Drosophila melanogaster, N/A, Xenograft
Applications
Validated:
ELISA, Western Blot
Cited:
Bioassay, ELISA Detection, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Product Specifications
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for Anti-PAR Polyclonal Antibody (Rabbit)
Application
Recommended Usage
ELISA
Western Blot
Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PAR/pADPr
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
Long Name
Poly [ADP-ribose] Polymer
Alternate Names
PAR
Additional PAR/pADPr Products
Product Specific Notices for Anti-PAR Polyclonal Antibody (Rabbit)
For research use only
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