ACE/CD143 Antibody (5-369) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09158

Novus Biologicals, part of Bio-Techne
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NBP3-09158
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 5-369

Format

BSA Free

Concentration

1 mg/ml

View all ACE/CD143 Antibodies »

Product Specifications

Immunogen

dendritic cells

Specificity

The mouse monoclonal antibody 5-369 recognizes an extracellular epitope of CD143, a 171 kDa type I transmembrane glycoprotein with metallopeptidase activity, expressed mainly on endothelial cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

Novus Biologicals Mouse ACE/CD143 Antibody (5-369) - BSA Free (NBP3-09158) is a monoclonal antibody validated for use in Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for ACE/CD143 Antibody (5-369) - BSA Free

Flow Cytometry: ACE/CD143 Antibody (5-369) - BSA Free [NBP3-09158]

Flow Cytometry: ACE/CD143 Antibody (5-369) - BSA Free [NBP3-09158]

Flow Cytometry: ACE/CD143 Antibody (5-369) [NBP3-09158] - Separation of human stimulated monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 ug/ml) GAM APC.
Flow Cytometry: ACE/CD143 Antibody (5-369) - BSA Free [NBP3-09158]

Flow Cytometry: ACE/CD143 Antibody (5-369) - BSA Free [NBP3-09158]

Flow Cytometry: ACE/CD143 Antibody (5-369) [NBP3-09158] - Surface staining pattern of human GM-CSF + IL-4 stimulated peripheral blood mononuclear cells stained using anti-human CD143 (5-369) purified antibody (concentration in sample 0,6 ug/ml) GAM APC.

Applications for ACE/CD143 Antibody (5-369) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ACE/CD143

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Long Name

Angiotensin I Converting Enzyme

Alternate Names

CD143, DCP1, Kininase II

Gene Symbol

ACE

Additional ACE/CD143 Products

Product Documents for ACE/CD143 Antibody (5-369) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ACE/CD143 Antibody (5-369) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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