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Express Discovery

Knowledge is power – obtaining as much high-quality information as possible early on in the protein bioprocessing workflow will be sure to set you up for success. When screening candidates and profiling immune responses can be done rapidly and effectively in the discovery stages, your downstream processes become quicker, cheaper and simpler.

protein bioprocessing
protein bioprocessing luminex

Multiplex with Luminex

Understanding how the immune system responds to your candidate therapeutic can make or break its success.

The earlier you have this data, the better - but running multiple assays for all your candidate therapeutics can take a lot of your sample, time and resources.

Discover a better way with ready-to-run and customizable Luminex cytokine panels. Save sample, time and money with quick, comprehensive immune profiling comparable to conventional assays – like ELISA and qPCR – with greater efficiency and throughput.

Simple Screening with Simple Western

Screening candidates is a key step in protein discovery – but the semi-quantitative, labor-intensive, and time-consuming nature of Western blotting can let you down.

Let our Simple Western platforms bring you back up! For super-fast, high-throughput antibody screening with quantitative results you can rely on, Simple Western technology is the simple choice.

The early bird catches the worm. Get ahead of your competition in the early stages of your workflow - rapidly perform charge distribution of mAbs, antibody screening, clone selection product titer, identity, and degradation analyses with Simple Western.

ProteinSimple Simple Western Instruments
sally sue

Sally Sue

Simple western size assays and chemiluminescence

Peggy and Sally Sue provide you with a fast and simple method for determining the time point of maximum protein concentration in cultures.

  • Process 24 samples in 3 hours or 96 samples ready overnight
  • Separate and analyze proteins between 2 kDa and 440 kDa
  • Input as little as 0.2 µg/µL of protein in just 5 µL of sample
  • Immunoassay or total protein analysis

 

peggy sue

Peggy Sue

Simple western size and charge assays and chemiluminescence

Peggy and Sally Sue provide you with a fast and simple method for determining the time point of maximum protein concentration in cultures.

  • Separate and analyze proteins by size or charge from 2-440 kDa
  • 96 samples ready overnight
  • Input as little as 0.2 µg/µL of protein in just 5 µL of sample
  • Immunoassay or total protein analysis

 

milo

Milo

Single-cell westerns

Welcome to the world of single-cell westerns!

  • Step away from population level resolution of Western blotting and off-target binding of flow cytometry, and embrace the single-cell revolution
  • Resolve single-cell heterogeneity in thousands of cells in just one run!

 

jess

Jess

Simple western size assays, chemiluminescence, fluorescence

After just 30 minutes of experimental setup, let Jess take care of your samples – quickly.

  • Fully automated solution for up to 25 samples
  • Fully analyzed results in just 3hours using just 3 uL of starting material
  • Use Jess's fluorescent capabilities and RePlexing workflow to multiplex your proteins for even higher throughput.

 

wes

Wes

Simple Western size assays and chemiluminescence

Wes quickly gets you down to pg-level sensitivity with just 3 µL of starting material.

  • Fully automated solution
  • Process 25 samples in just 3 hours
  •  With HDR detection profile and analysis Wes gets you up to 6 logs of dynamic range. 

 

nano pro

NanoPro 1000

Simple Western charge assays and chemiluminescence

NanoPro 1000 can give you all the details on your proteins, using just 25 cells!

  • Fully automated solution
  • Process 96 samples overnight
  • With HDR detection profile and analysis Wes gets you up to 6 logs of dynamic range. 

 

 

Take Charge Of Discovery

Monitoring post-translational modifications through charge heterogeneity and IgG analysis of your protein therapeutic candidate is an important quality requirement for regulatory authorities. But, what if you could easily and quickly obtain this information during the discovery stages? You could make early, yet informed decisions on candidates – saving you precious time downstream.

Reproducible results in under 35 minutes!

Discover how to get quantitative analysis of identity, purity and heterogeneity profiles of biopharmaceuticals in a snap!

maurice c

Meet Maurice C

How about quantitative pl and charge heterogeneity analysis in less than 10 minutes?

maurice s

Meet Maurice S

Getting IgG purity analysis that meets regulatory requirements needn’t be laborious. With Maurice S’s ready-to-go CE-SDS or CE-SDS PLUS cartridges you get fast and robust IgG purity data in just 35 minutes.

ice3

iCE3

With iCE3 you can get high-resolution, quantitative charge heterogeneity data in less time than it takes to have a cup of coffee. It'll analyze your toughest samples and most challenging proteins with ease.

Detect, Visualize, and Validate Early With RNAScope™

Be confident in your therapeutic and validate specificity, safety, and efficacy early on by seeing it with your own eyes. With RNAscope you can visualize the spatial expression and biodistribution of target(s) across multiple tissues.

What’s more?

Get orthogonal validation with lower background noise compared to traditional RNA detection techniques and super sensitivity - only 6 Z pairs are required to obtain a signal. Or check out BaseScope™ Assays that are even further refined to detect as few as 1-3 Z pairs!

Take things one step further with RNA-Protein Co-Detection Assays

If you need to simultaneously examine cell-type specific gene expression and identify cellular sources of secreted proteins, RNA-Protein Co-Detection assays have got you covered.

protein bioprocessing
Exosomes

Extend Your Capabilities with Exosome Diagnostics

RNA, DNA and protein profiling can accelerate your discovery process – but conventional cell lysis techniques can destroy important material and disturb cell conditions.

Exosome isolation with Exolution Plus will keep your RNA, DNA and proteins safe and intact – allowing you to perform longitudinal and dynamic analysis with confidence.

Discover a better way to profile your analytes with Exolution Plus.