Adenosine A1R: Small Molecules and Peptides
Adenosine A1 Receptor (ADORA1, Adenosine A1R) is an adenosine receptor that belongs to the G protein-coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The Adenosine A1R inhibits adenylyl cyclase and plays a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication.
Products:
18 results for "Adenosine A1R Small Molecules and Peptides" in Products
18 results for "Adenosine A1R Small Molecules and Peptides" in Products
Adenosine A1R: Small Molecules and Peptides
Adenosine A1 Receptor (ADORA1, Adenosine A1R) is an adenosine receptor that belongs to the G protein-coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The Adenosine A1R inhibits adenylyl cyclase and plays a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication.
Products:
Endogenous adenosine receptor agonist
| Chemical Name: | 9-β-D-Ribofuranosyl-9H-purin-6-amine |
| Purity: | ≥98% (HPLC) |
PDE inhibitor (non-selective)
| Chemical Name: | 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
High affinity adenosine agonist
| Alternate Names: | 5'-N-Ethylcarboxamidoadenosine |
| Chemical Name: | 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide |
| Purity: | ≥98% (HPLC) |
Potent adenosine receptor antagonist
| Chemical Name: | 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine |
| Purity: | ≥98% (HPLC) |
Highly selective A1 agonist
| Chemical Name: | N-Bicyclo[2.2.1]hept-2-yl-5'-chloro-5'-deoxyadenosine |
| Purity: | ≥98% (HPLC) |
High affinity adenosine A1 receptor antagonist
| Alternate Names: | CPT,8-Cyclopentyltheophylline |
| Chemical Name: | 8-Cyclopentyltheophylline |
| Purity: | ≥98% (HPLC) |
Adenosine receptor antagonist
| Alternate Names: | Xanthine amine congener |
| Chemical Name: | N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Adenosine receptor agonist
| Alternate Names: | 2-CADO |
| Chemical Name: | 6-Amino-2-chloropurine riboside |
| Purity: | ≥98% (HPLC) |
A1 and A2B antagonist. CNS stimulant
| Chemical Name: | 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
Adenosine receptor antagonist
| Chemical Name: | 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid |
| Purity: | ≥98% (HPLC) |
Selective A1 antagonist
| Chemical Name: | 8-Cyclopentyl-1,3-dipropylxanthine |
| Purity: | ≥98% (HPLC) |
Selective A1 antagonist
| Alternate Names: | Rolofylline |
| Chemical Name: | 8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
Potent and selective A1 agonist
| Alternate Names: | CCPA |
| Chemical Name: | 2-Chloro-N-cyclopentyladenosine |
| Purity: | ≥98% (HPLC) |
Highly selective and potent A1 receptor agonist
| Chemical Name: | 2-Chloro-N-cyclopentyl-2'-methyladenosine |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of A1 receptors
| Chemical Name: | (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator (PAM) of A1 receptors; also allosteric partial agonist in absence of orthosteric agonist
| Chemical Name: | [2-Amino-4-[3-(trifluoromethyl)phenyl]-3-thienyl]phenylmethanone |
| Purity: | ≥98% (HPLC) |
Potent and selective A1 agonist
| Alternate Names: | CPA |
| Chemical Name: | N-Cyclopentyladenosine |
| Purity: | ≥99% (HPLC) |
Potent and selective A1 agonist
| Chemical Name: | N-Cyclohexyl-2'-O-methyladenosine |
| Purity: | ≥99% (HPLC) |
