XCC
Tocris Bioscience, part of Bio-Techne | Catalog # 4220
Adenosine receptor antagonist
Key Product Details
Description
Adenosine receptor antagonist
Product Description
XCC is an adenosine receptor antagonist (Ki values are 42, 68 and 1130 nM for A1, A2B and A2A receptors).Product Specifications
Molecular Weight
386.40
Formula
C19H22N4O5
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
CAS Number
96865-83-7
PubChem ID
126079
InChI Key
QTMMGCYGCFXBFI-UHFFFAOYSA-N
SMILES
O=C1N(CCC)C(C(NC(C3=CC=C(OCC(O)=O)C=C3)=N2)=C2N1CCC)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 19.32 | 50 |
Preparing Stock Solutions
for XCC
The following data is based on the product molecular weight 386.40
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 5.18 mL | 25.88 mL | 51.76 mL |
| 2.5 mM | 1.04 mL | 5.18 mL | 10.35 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.18 mL |
| 25 mM | 0.10 mL | 0.52 mL | 1.04 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sebastiao The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 1990 PMID: 2257444
- Thummler and Dunwiddie Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 2000 PMID: 10758091
- Jarvis Autoradiographic characterization of high-affinity adenosine A2 receptors in the rat brain. Brain Res. 1989 PMID: 2713675
Product Specific Notices for XCC
For research use only
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